Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Service Management Optimization (SMO) Analyst
$79K - $122K *
Analyze and optimize IT service management workflows for a Department of War agency, enhancing service delivery and efficiency through data-driven insights, process improvements, and collaboration wit...
3 weeks ago
Assistant Nurse Manager, Cardiac Cath Lab
$218K - $251K *
Pioneer patient care excellence by leading collaborative teams, ensuring compliance with clinical standards, and implementing best practices across multiple locations to enhance safety and quality of...
Reposted 5 days ago
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
3 days ago
$80K - $110K *
Grow your career with a role pivotal in safeguarding classified information systems. Collaborate with a dynamic IT team, conduct security audits, and ensure compliance through comprehensive monitoring...
3 weeks ago
$80K - $110K *
Lead comprehensive cyber security efforts to protect classified systems. Collaborate with IT teams to ensure compliance with security standards, conduct audits, manage risks, and respond to incidents...
3 weeks ago
$100K - $125K *
Join our dynamic finance team as you drive margin and profitability through detailed analysis and strategic insights. Collaborate with senior leadership to transform data into actionable initiatives t...
1 week ago
Clinical Nurse III - Operating Room - Days
$100K - $120K *
Contribute to transformative cancer care by delivering exceptional surgical support in the operating room, collaborating with healthcare teams, and ensuring patient safety in a dynamic clinical enviro...
Reposted 1 week ago
Senior Director Product Analytics
$254K - $445K *
Drive impactful product analytics strategies to enhance user engagement and adoption. Lead a team to leverage data insights, optimize product usage, and support business growth through innovative AI s...
6 days ago
Principal Developer, Oncology Data & AI Systems (2 available)
$117K - $201K *
Elevate your career by leading data science initiatives in Oncology R&D. Drive the modernization of data capture and optimize scalable data pipelines to enhance advanced analytics and AI/ML applicatio...
3 weeks ago
Test Lead II - Healthcare Payer Testing
$90K - $120K *
Champion quality assurance in healthcare payer systems by leading test planning, execution, and defect management. Collaborate with cross-functional teams to ensure compliance and deliver high-quality...
1 week ago
$80K - $95K *
Unlock innovative solutions in Live, Virtual, and Constructive Training initiatives, enhancing operational readiness and integration of Information Warfare systems. Collaborate with diverse stakeholde...
2 weeks ago
$175K - $210K *
Elevate your career by owning the sales cycle for major employers, building strategic partnerships, and driving innovative health programs that shape enterprise success and market presence...
3 weeks ago
$90K - $113K *
Join a team that's transforming healthcare through innovative software solutions. Collaborate with engineers and cross-functional partners to design, build, and deploy scalable cloud-native applicatio...
3 weeks ago
$85K - $100K *
Unlock potential by leading nursing operations and ensuring quality care for residents. Collaborate with staff and families to create a compassionate environment while managing clinical and administra...
1 week ago
Software Engineer/Sr Software Engineer
$120K - $170K *
Develop and enhance Python services for pharmacy claims processing. Collaborate across teams to deliver high-quality solutions while gaining expertise in the pharmacy benefits domain. Embrace a hybrid...
2 weeks ago
$150K - $180K *
Lead Corporate FP&A initiatives, driving budgeting, forecasting, and performance management. Oversee financial analysis and reporting while enhancing systems and dashboards for improved decision-makin...
2 weeks ago
VP OF SALES - EAST COAST - HEALTHCARE
$160K - $200K *
Empower your career by leading a high-performing sales team to drive profitable growth in the healthcare sector. Develop and execute strategic sales initiatives, foster client relationships, and ensur...
3 weeks ago
Senior Analyst, Data & Analytics (Pharmacy Analytics & Reporting) - REMOTE
$95K - $115K *
Unlock your potential in a senior analyst role focused on data analysis and reporting. Collaborate with stakeholders to deliver insights that drive strategic decisions and enhance business performance...
Reposted today
Lead Director, Medical Benefit Portfolio Product Management
$100K - $231K *
Innovate portfolio strategies by leveraging market insights and driving execution. Collaborate with cross-functional teams to enhance product offerings and achieve business objectives in the healthcar...
3 weeks ago
$90K - $110K *
Advance your career by delivering critical cost estimates for federal programs. Collaborate with a dynamic team to enhance national security through effective budgeting and analysis of advanced commun...
4 days ago
$85K - $100K *
Take ownership of patient care by collaborating on treatment plans, assessing needs, and ensuring comprehensive support in a dynamic healthcare environment. Elevate your nursing career while making a...
6 days ago
$80K - $106K *
Lead the charge in providing exceptional rehabilitative care as a Physical Therapy Assistant, collaborating with a dedicated team to enhance participant independence and well-being through personalize...
2 weeks ago
Senior Manager, State and Local Government Relations (Western US)
$150K - $268K *
Drive state and local government relations across 25 states, managing legislative efforts and stakeholder engagement to advance business goals. Collaborate with internal teams and external partners to...
6 days ago
Senior Manager, State and Local Government Relations (Western US)
$168K - $268K *
Reimagine state and local government relations by leading legislative efforts across 25 states. Build relationships with policymakers, drive business development, and advocate for healthcare and techn...
6 days ago
$85K - $100K *
Elevate patient care by collaborating on comprehensive care plans, ensuring accountability for patient status, and utilizing therapeutic techniques in a dynamic healthcare environment. Join a team ded...
3 days ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.