Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
$85K - $93K *
Champion quality excellence by enhancing ISO compliance, leading improvement initiatives, and ensuring regulatory adherence across multiple quality systems. Collaborate on critical investigations and...
Reposted today
$121K - $181K *
Advance your career by leading operational excellence in outpatient clinics, ensuring compliance with regulations, optimizing workflows, and enhancing patient care. Collaborate with diverse teams to a...
5 days ago
$121K - $181K *
Transform healthcare operations by leading outpatient clinics to achieve excellence in patient care, safety, and satisfaction. Drive strategic initiatives, optimize workflows, and foster partnerships...
5 days ago
$80K - $95K *
Join a team that's redefining inpatient coding operations, ensuring quality and compliance while optimizing workflows. Lead a dedicated team to enhance documentation practices and support financial he...
1 week ago
$110K - $130K *
Lead the charge in leveraging web analytics to drive insightful data solutions, establishing KPIs, implementing tracking strategies, and delivering actionable recommendations for optimizing client onl...
Reposted 3 weeks ago
Remote Director of Clinical Reimbursement
$110K - $130K *
Unlock potential by leading clinical reimbursement strategies across skilled nursing facilities, ensuring compliance and optimal performance through collaboration with multidisciplinary teams to enhan...
Reposted 3 weeks ago
Senior Data Engineer (Analytics & Applied AI)
$113K - $188K *
Lead the charge in building robust data platforms that transform complex datasets into actionable insights. This senior role demands expertise in software and data engineering, with a focus on quality...
5 days ago
$85K - $100K *
Innovate nursing education by guiding professional development, enhancing clinical skills, and fostering a culture of inquiry. Collaborate with staff to achieve excellence in patient care through effe...
2 weeks ago
$110K - $140K *
Drive innovation and build impactful solutions across the full technology stack in a high-velocity environment. Collaborate with cross-functional teams and leverage AI tools to enhance productivity an...
Reposted 3 weeks ago
$80K - $95K *
Elevate patient care by delivering precise radiation therapy, ensuring comfort and safety. Collaborate with a skilled team to operate advanced equipment and support cancer patients through their treat...
1 week ago
$85K - $100K *
Empower patients by delivering precise radiation therapy, ensuring comfort and safety. Collaborate with a skilled team to operate advanced equipment, monitor treatment, and provide compassionate care...
1 week ago
Information System Analyst 2 (5461C), Office of Laboratory Animal Care #89443
$78K - $99K *
Join a dynamic team to provide IT services, manage systems, and support research initiatives. Leverage your skills in software development, database administration, and technical support to enhance op...
1 week ago
Client Growth & Success, Senior Manager- Enterprise Accounts
$130K - $145K *
Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...
1 week ago
Diabetes Educator I, II or III, Ambulatory
$102K - $158K *
Help us empower patients through diabetes education and nutrition therapy. Collaborate with healthcare teams to create personalized care plans, enhancing quality of life for individuals managing diabe...
3 days ago
Diabetes Educator I, II or III, Ambulatory
$102K - $158K *
Join a team that's dedicated to empowering patients through diabetes education and nutrition therapy. Collaborate with healthcare professionals to create personalized care plans that enhance quality o...
3 days ago
Bioinformatics Scientist I/II/Senior
$125K - $180K *
Unlock potential by designing cutting-edge algorithms to enhance early cancer detection through analysis of epigenomic features in cell free DNA, collaborating within a dynamic team throughout the ful...
3 weeks ago
$113K - $180K *
Empower strategic decision-making by leading complex data analysis initiatives, developing actionable insights, and guiding innovative business solutions across cross-functional teams to drive impactf...
5 days ago
$124K - $198K *
Lead the charge in driving strategic decision-making through advanced data analysis. Collaborate with cross-functional teams to develop actionable insights and innovative solutions that address high-i...
5 days ago
Chief, Complex Digestive Health (San Francisco, CA)
$300K - $350K *
Help us elevate our comprehensive digestive health program through strategic leadership, clinical excellence, and innovative care models. Drive collaboration across specialties to enhance patient outc...
2 weeks ago
Service Management Optimization (SMO) Analyst
$79K - $122K *
Analyze and optimize IT service management workflows for a Department of War agency, enhancing service delivery and efficiency through data-driven insights, process improvements, and collaboration wit...
3 weeks ago
Assistant Nurse Manager, Cardiac Cath Lab
$218K - $251K *
Pioneer patient care excellence by leading collaborative teams, ensuring compliance with clinical standards, and implementing best practices across multiple locations to enhance safety and quality of...
Reposted 5 days ago
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
3 days ago
$80K - $110K *
Grow your career with a role pivotal in safeguarding classified information systems. Collaborate with a dynamic IT team, conduct security audits, and ensure compliance through comprehensive monitoring...
3 weeks ago
$80K - $110K *
Lead comprehensive cyber security efforts to protect classified systems. Collaborate with IT teams to ensure compliance with security standards, conduct audits, manage risks, and respond to incidents...
3 weeks ago
$100K - $125K *
Join our dynamic finance team as you drive margin and profitability through detailed analysis and strategic insights. Collaborate with senior leadership to transform data into actionable initiatives t...
1 week ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.