Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Senior Software Engineer (AI Healthcare Operations) (US Candidates Only)
$145K - $175K *
Join a team that's redefining software engineering by owning platform modules, building AI agents, and creating integrations. Collaborate closely with engineers to deliver innovative solutions and ens...
2 days ago
$110K - $130K *
Unlock potential by driving customer growth and implementation strategies in a dynamic environment. You'll deepen relationships with key partners, leveraging technical fluency to enhance value and est...
Reposted 3 weeks ago
$75K - $121K *
Contribute to cutting-edge research by managing advanced instrumentation, performing quality control, and fostering collaboration. Support innovative assay development and oversee lab operations to dr...
Reposted 2 weeks ago
$100K - $125K *
Manage and analyze professional liability and medical malpractice claims, ensuring compliance and optimal outcomes through collaboration with counsel and specialty resources. Drive strategic claim res...
3 weeks ago
Healthcare Payment Solutions Consultant - Enterprise Market
$126K - $154K *
Transform healthcare payment solutions by driving business growth and optimizing client relationships. Leverage your expertise to develop tailored proposals and secure long-term partnerships with larg...
4 days ago
Applied AI Security Architect - Healthcare & Life Sciences
$315K - $380K *
Champion enterprise security and compliance for healthcare clients, guiding them in deploying AI solutions safely. Engage with technical leaders to address security architecture and regulatory needs...
3 days ago
$140K - $200K *
Champion growth by developing sales strategies, nurturing client relationships, and identifying market opportunities. Collaborate with teams to enhance offerings and drive success in the pharma and bi...
4 days ago
Manager, Risk Adjustment Encounter Data Reconciliation
$118K - $157K *
Lead the charge in encounter data reconciliation, ensuring accurate submissions to regulatory bodies. Oversee technical operations, manage staff, and enhance compliance processes to protect risk score...
2 weeks ago
Senior ITCR / Requirements Analyst
$79K - $122K *
Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...
3 days ago
Senior ITCR / Requirements Analyst
$79K - $122K *
Join a team that's driving innovation as you lead critical IT capability analysis, mentorship, and strategic decision-making. Utilize your expertise to enhance enterprise IT initiatives and deliver im...
3 weeks ago
Business Analyst, Commercial Development
$63K - $99K *
Empower the Product Category Management team by analyzing data trends, generating reports, and supporting strategic decisions. Collaborate across departments to enhance product performance and mentor...
5 days ago
Field Remote Nurse Practitioner/Physician Assistant
$113K - $169K *
Provide comprehensive in-home assessments for patients with chronic care needs, collaborating with an interdisciplinary team to ensure quality, cost-effective healthcare outcomes while adhering to reg...
1 week ago
$80K - $100K *
Drive your career forward by supporting compliance initiatives in a dynamic fintech environment. Collaborate with leadership and bank partners to ensure regulatory adherence while developing processes...
2 weeks ago
$75K - $90K *
Advance patient care with comprehensive assessments and referrals, ensuring timely clinical evaluations. Collaborate with hospital staff for optimal patient admissions and care management across behav...
3 weeks ago
Manager - Annual Wellness Visit Programs
$85K - $119K *
Transform healthcare delivery by overseeing Annual Wellness Visit programs, enhancing patient engagement, and leading a dedicated team. Drive operational excellence through vendor management, billing...
2 weeks ago
$86K - $129K *
Optimize client relationships by providing strategic account management and advanced customer service solutions, ensuring seamless operations for large accounts and exceeding client expectations throu...
Reposted 2 weeks ago
Senior Corporate Development and Planning Analyst
$95K - $115K *
Take ownership of financial and operational analysis for strategic initiatives, delivering critical insights and reporting to support executive decision-making while driving accuracy and efficiency in...
Reposted 1 week ago
Senior Program Analyst - Policy
$69K - $107K *
Drive impactful program analysis by interpreting complex HUD regulations and translating them into actionable guidance for operational staff, ensuring compliance and effective policy implementation ac...
1 week ago
$90K - $110K *
Empower healthcare innovation by translating clinical needs into effective AI solutions. Own the technical lifecycle, collaborate with stakeholders, and ensure successful deployments while enhancing o...
3 weeks ago
Executive Director, Financial Planning & Commercial Growth
$175K - $210K *
Join a team that's shaping the future of innovation in cancer research by leading financial planning and commercialization efforts to support strategic growth and decision-making across an impactful o...
Reposted 1 week ago
Business Intelligence Lead, Conversational Channels
$117K - $161K *
Join a team that's redefining member engagement through advanced analytics and strategic leadership. Drive analytics strategy, mentor engineers, and enhance conversational experiences across innovativ...
5 days ago
$78K - $88K *
Join us to perform actuarial analyses and support healthcare consulting projects. Collaborate with multidisciplinary teams to develop insights, maintain models, and communicate findings effectively wh...
1 week ago
$156K - $234K *
Join us in leading clinical and business operations across multiple facilities, focusing on program development, fiscal management, and quality improvement to enhance patient care and community relati...
Reposted 1 week ago
$80K - $95K *
Optimize patient care by delivering exceptional perioperative nursing support across all surgical phases. Collaborate with clinical teams to ensure safety, efficiency, and compassionate care, directly...
5 days ago
$110K - $130K *
Join a team that's redefining software engineering by integrating AI tools to accelerate the development process. Transform requirements into reliable solutions while ensuring quality, security, and m...
3 weeks ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.