Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Revenue Cycle Jobs in South Dakota

Sort By: Relevance

$100K - $120K *

Engage with diverse stakeholders to drive sales initiatives, source new clients, and expand existing accounts. Leverage strong prospecting and strategic relationship-building skills in a fast-paced, c...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$121K - $202K *

Shape the future of performance engineering by leading QA delivery for high-transaction healthcare platforms. Drive strategy, mentor teams, and enhance the reliability and scalability of critical syst...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$108K - $148K *

Shape the future of our global real estate portfolio by executing complex transactions and driving asset performance. Collaborate with cross-functional teams to optimize our diverse international site...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$123K - $164K *

Drive end-to-end design execution for major data center projects, leading multidisciplinary teams to ensure alignment with safety, sustainability, and commercial goals throughout the project lifecycle...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Transform the future of bulk power system reliability by leading strategic assessments, performance analysis, and data integration. Drive innovative methodologies and collaborate with multidisciplinar...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$290K - $350K *

Pioneer sales innovation by targeting major enterprises for GRC solutions. You’ll drive revenue growth through cold prospecting, strategic planning, and customer engagement, making a significant impac...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform production planning by leading a dynamic team to optimize non-sterile compounded production. Drive strategic planning, manage capacity, and ensure alignment with demand forecasts while foste...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by leading tax processes and client relationships while mentoring your team. Drive strategic solutions in a collaborative environment with a focus on maximizing tax benefits across di...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$253K - $398K *

Shape the future of public sector sales by driving growth and building relationships with key stakeholders. Leverage your expertise to uncover opportunities and deliver impactful digital solutions tha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $185K *

Lead client engagements in Real-World Data solutions, ensuring operational excellence and strong outcomes. Collaborate cross-functionally to translate client objectives into actionable plans, driving...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $207K *

Lead strategic statistical initiatives for clinical development programs, ensuring rigorous study design and data analysis. Collaborate with cross-functional teams and regulatory authorities to drive...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive high-value B2B paid media strategies and growth across multiple channels while leading a team of media professionals, ensuring client success and operational excellence in performance marketing...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $250K *

Champion innovative financing strategies to drive growth in a dynamic energy infrastructure company. Oversee capital funding, asset finance, and deal design while building a high-performing finance te...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$150K - $180K *

Lead the charge in shaping product strategy and execution for a key applications portfolio, driving innovation and growth through AI integration while mentoring a high-performing team in a dynamic hea...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $210K *

Transform retail sales strategies and lead a dynamic team to achieve revenue goals. Drive account management, develop talent, and collaborate with cross-functional teams to enhance product offerings a...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$145K - $175K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$140K - $150K *

Reimagine data management as a Senior Technical Product Owner, leading cross-functional teams to drive product vision and execution. Oversee complex SQL Server systems and cloud-native applications, e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead Corporate FP&A initiatives, driving budgeting, forecasting, and performance management. Oversee financial analysis and reporting while enhancing systems and dashboards for improved decision-makin...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Pioneer a new field sales organization by leading a team of Territory Managers to drive growth through independent agencies. Collaborate cross-functionally to enhance performance and achieve productio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform operational excellence by leading a dynamic team to enhance client satisfaction, streamline processes, and drive continuous improvement across remote Central Operations. Collaborate with pee...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$100K - $150K *

Champion the evolution of Workday by leading enhancements and driving cross-functional collaboration. Utilize your PM and BA expertise to translate business needs into scalable solutions, ensuring ali...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $175K *

Elevate your career by leading a high-performing Security Engineering and CloudSecOps team. Drive security initiatives across cloud and enterprise environments, ensuring compliance and resilience whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $160K *

Lead governance initiatives in a multi-cloud environment, managing a team to secure and optimize cloud operations. Oversee compliance, develop policies, and optimize costs while ensuring alignment wit...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.