Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$80K - $95K *

Pioneer the future of construction project management by leading teams, ensuring safety, quality, and profitability while delivering projects on time and within budget. Drive collaboration with stakeh...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$111K - $145K *

Lead transformative IT projects from inception to completion, ensuring timely delivery and budget adherence. Collaborate across departments to translate business needs into actionable plans while mana...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $177K *

Lead and develop a distributed team of Project Coordinators, enhancing operational health and governance across complex automation deployments while driving continuous improvement and collaboration wi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K *

Unlock potential by driving enterprise account strategies and engaging technical leaders. Collaborate with AEs to create meaningful outreach and build a pipeline that converts, focusing on quality int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $163K *

Champion client success by leading project teams to deliver high-quality card processing solutions. Drive enhancements, manage complex implementations, and ensure client satisfaction through effective...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $123K *

Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Transportation

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$108K - $149K *

Drive revenue operations excellence by enhancing MSSP processes and systems. Collaborate with cross-functional teams to operationalize strategies, streamline workflows, and support partner lifecycle m...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $135K *

Shape the future of healthcare by leading impactful operations strategies. Collaborate with senior leaders to innovate, optimize processes, and drive transformation across multiple business units, enh...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $235K *

Transform the healthcare sales landscape by leading a dynamic team to drive revenue and margin growth. Leverage your expertise to achieve commercial objectives while fostering strong relationships and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$168K *

Elevate your career by leading a dynamic team in cyber security, ensuring robust protection of assets through innovative strategies and incident response. Collaborate across departments to enhance ris...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $120K *

Drive collaboration across teams to coordinate scientific data, streamline processes, and enhance operational efficiency. This role requires strong judgment and the ability to manage cross-functional...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$231K - $340K *

Advance enterprise procurement value through strategic insights and influence. Lead high-stakes engagements, build enduring frameworks, and coach teams while presenting compelling value narratives to...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in clinical study start-up operations, driving team development and ensuring timely site activation. Collaborate cross-functionally to enhance processes, meet regulatory standards, and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Manage and optimize the digital marketing strategy for oncology products, enhancing customer engagement through innovative digital assets. Lead cross-functional teams to execute comprehensive marketin...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$206K - $343K *

Transform your career by leading AI & Data initiatives for Energy Providers. Drive growth, build client relationships, and develop a high-performing team while delivering innovative solutions that add...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$147K - $220K *

Champion transformative health solutions by managing key client relationships, driving sales, and collaborating across teams to enhance Verily's impact in Life Sciences. Leverage expertise to unlock n...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$78K - $119K *

Lead the charge in operational excellence by governing product lifecycle standards, translating business needs into actionable specifications, and supporting AI-enabled solutions for continuous improv...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the enhancement of finance systems in a dynamic environment, focusing on optimizing NetSuite and integrating additional solutions. This role involves strategy, system configuration, and process i...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $186K *

Manage legal services for indirect sourcing, delivering strategic counsel and project management. Negotiate vendor agreements and ensure compliance while collaborating with stakeholders to support bus...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform the 340B Drug Program by ensuring compliance, optimizing operations, and leveraging clinical pharmacy expertise to enhance patient care and resource allocation for underserved populations...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$145K - $160K *

Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.