Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$174K - $204K *

Drive transformative growth by leading strategic initiatives that redefine operational models and enhance market performance across franchise systems. Collaborate with cross-functional teams to ensure...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$136K - $171K *

Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $230K *

Join a team that's driving innovation in biopharma partnerships. Leverage your expertise to identify and advance strategic opportunities, influence cross-functional decisions, and manage alliances tha...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$134K - $215K *

Empower our team by leading operational solutions and client services. Drive strategic initiatives, enhance product delivery, and ensure exceptional quality across digital platforms while collaboratin...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the monthly close and day-to-day accounting operations, ensuring accuracy and efficiency as the business scales. Collaborate with cross-functional teams to enhance processes and implement automat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$235K - $270K *

Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $210K *

Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$168K - $228K *

Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$235K - $265K *

Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$165K - $185K *

Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$207K - $346K *

Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $175K *

Unlock potential by leading enterprise data engineering initiatives, driving platform modernization, and enhancing operational excellence. Collaborate with cross-functional teams to deliver scalable...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$160K - $200K *

Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$113K - $197K *

Drive automation and AI initiatives in claims operations, enhancing efficiency and accuracy. Lead a team to optimize workflows, manage vendor performance, and ensure compliance while delivering measur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$144K - $191K *

Unlock potential by leading the Automated Operations capability within Member Services. Oversee AI support experiences, enhance team productivity, and drive continuous improvement to elevate member in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Lead quality operations to ensure data accuracy and compliance in healthcare. Drive improvements through audits, data analysis, and technology integration, fostering a culture of excellence across tea...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $275K *

Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K - $177K *

Lead coding operations and education initiatives to ensure compliance, accuracy, and optimal reimbursement across the organization. Manage staff training and oversee coding standards while collaborati...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Accelerate progress at the forefront of healthcare sales by driving revenue growth and expanding strategic partnerships in the RCM sector. Lead comprehensive sales strategies to engage large clients a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$177K - $221K *

Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by leading financial operations in a mission-driven healthcare organization. As a key executive, you'll oversee budgeting, compliance, and strategic planning to ensure sustainable gro...

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $170K *

Shape the future of pricing strategy by leading complex deal governance and analytics. Collaborate across teams to enhance deal integrity and leverage AI-driven tools for efficient pricing models, ens...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $215K *

Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.