Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Director, Franchise Strategy & Transformation
$174K - $204K *
Drive transformative growth by leading strategic initiatives that redefine operational models and enhance market performance across franchise systems. Collaborate with cross-functional teams to ensure...
Today
Senior Manager, Clinical Operations
$136K - $171K *
Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...
1 week ago
$190K - $230K *
Join a team that's driving innovation in biopharma partnerships. Leverage your expertise to identify and advance strategic opportunities, influence cross-functional decisions, and manage alliances tha...
6 days ago
VP, Operations (Digital Solutions) - Remote
$134K - $215K *
Empower our team by leading operational solutions and client services. Drive strategic initiatives, enhance product delivery, and ensure exceptional quality across digital platforms while collaboratin...
Yesterday
$100K - $120K *
Lead the monthly close and day-to-day accounting operations, ensuring accuracy and efficiency as the business scales. Collaborate with cross-functional teams to enhance processes and implement automat...
3 days ago
Director, Managed Markets - Regional - Central
$235K - $270K *
Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...
2 weeks ago
Director, Chronic Practice Liaison - Remote
$126K - $210K *
Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...
3 weeks ago
Director, QMS Process Owner - Global Change Control Management
$168K - $228K *
Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...
2 days ago
Vice President of Product Management
$235K - $265K *
Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...
2 weeks ago
Group Account Director (Medical Affairs)
$165K - $185K *
Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...
Reposted 1 week ago
Medical Director, Post Acute Care
$207K - $346K *
Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...
Reposted 3 days ago
$165K - $175K *
Unlock potential by leading enterprise data engineering initiatives, driving platform modernization, and enhancing operational excellence. Collaborate with cross-functional teams to deliver scalable...
Reposted 1 week ago
$160K - $200K *
Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...
3 weeks ago
Director, Claims Process Optimization ( Facets Required)
$113K - $197K *
Drive automation and AI initiatives in claims operations, enhancing efficiency and accuracy. Lead a team to optimize workflows, manage vendor performance, and ensure compliance while delivering measur...
1 week ago
Director, Automation Operations
$144K - $191K *
Unlock potential by leading the Automated Operations capability within Member Services. Oversee AI support experiences, enhance team productivity, and drive continuous improvement to elevate member in...
2 weeks ago
$130K - $160K *
Lead quality operations to ensure data accuracy and compliance in healthcare. Drive improvements through audits, data analysis, and technology integration, fostering a culture of excellence across tea...
2 weeks ago
Director / Senior Director / Executive Director, Regulatory Affairs
$210K - $275K *
Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...
Reposted 1 week ago
Director, PB Coding Operations & Education
$122K - $177K *
Lead coding operations and education initiatives to ensure compliance, accuracy, and optimal reimbursement across the organization. Manage staff training and oversee coding standards while collaborati...
1 week ago
RCM Regional Sales Manager, Strategic
$110K - $130K *
Accelerate progress at the forefront of healthcare sales by driving revenue growth and expanding strategic partnerships in the RCM sector. Lead comprehensive sales strategies to engage large clients a...
3 weeks ago
Associate Director, Access Strategy and Marketing
$177K - $221K *
Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...
3 days ago
$150K - $180K *
Unlock potential by leading financial operations in a mission-driven healthcare organization. As a key executive, you'll oversee budgeting, compliance, and strategic planning to ensure sustainable gro...
4 weeks ago
Director, Business Development
$120K - $150K *
Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...
Reposted 2 weeks ago
Sr. Manager, Pricing and Deal Desk
$160K - $170K *
Shape the future of pricing strategy by leading complex deal governance and analytics. Collaborate across teams to enhance deal integrity and leverage AI-driven tools for efficient pricing models, ens...
4 weeks ago
$125K - $190K *
Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...
1 week ago
Account Director, Global Strategic Accounts
$175K - $215K *
Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...
3 weeks ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.