Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Clinic Director Physical Therapist
$80K - $95K *
Join a team that's dedicated to excellence in outpatient orthopedic care, where you'll lead clinical operations, mentor a dynamic team, and ensure positive patient outcomes while maintaining an active...
4 weeks ago
$261K - $391K *
Shape the future of oncology clinical research by leading pivotal trials, ensuring regulatory compliance, and guiding strategic medical initiatives within a collaborative global team...
Reposted 2 weeks ago
Senior Director, Risk Management
$160K - $200K *
Transform risk management by leading a national team focused on claims, clinical risk reduction, and innovative AI solutions to improve outcomes. Drive strategic oversight and implement best practices...
4 weeks ago
$110K - $130K *
Transform client marketing strategies by leading interdisciplinary teams, delivering innovative solutions based on research and best practices, while fostering long-lasting client relationships to ach...
3 weeks ago
Director Medical and Multi Specialty Clinics
$110K - $130K *
Unlock potential by leading the development of a multi-specialty clinic, enhancing clinical efficiency, financial viability, and staff performance while ensuring a patient-centered focus and complianc...
6 days ago
$60K - $107K *
Advance clinic operations by leading staff, optimizing workflows, and ensuring compliance. Collaborate with clinical teams to enhance patient experience and achieve organizational goals while fosterin...
Yesterday
$250K - $300K *
Lead the charge in transforming cardiovascular care. Oversee clinical teams, ensuring high standards, build partnerships, and shape value-based care strategies to improve patient outcomes and provider...
Reposted 4 weeks ago
Associate Director, Enterprise Architecture, Global Commercial & Medical IT
$152K - $209K *
Explore innovative technology solutions as you define and govern enterprise architecture for Commercial & Medical domains, ensuring alignment with business strategy and regulatory compliance while dri...
1 week ago
Director of Quality Management
$95K - $115K *
Join a dynamic team to oversee quality management initiatives, ensuring compliance with regulatory standards and enhancing patient care outcomes through effective performance improvement strategies an...
3 weeks ago
Clinical Manager - Neuroscience
$85K - $100K *
Advance your career by managing clinical operations in a dynamic neuroscience department. Oversee quality care, staff development, and patient satisfaction while driving strategic initiatives and fost...
Today
$95K - $120K *
Unlock potential by driving medical research and strategic communications. Collaborate with clients and teams to ensure scientific accuracy and propel brand objectives, shaping innovative solutions in...
1 week ago
Senior Medical Director, Pharmacovigilance and Safety
$306K - $343K *
Join our team to lead pharmacovigilance efforts, ensuring safety oversight for investigational products, aligning strategies with regulatory requirements, and collaborating across teams to uphold part...
3 weeks ago
TMS Clinical & Research Service Manager
$88K - $190K *
Lead and innovate in clinical operations and research for TMS services. Drive efficiency and compliance while managing teams and financial performance in a fast-paced healthcare environment. Shape the...
4 weeks ago
TMS Clinical & Research Service Manager
$88K - $190K *
Lead and optimize clinical operations while managing TMS services and research initiatives. Oversee staff, ensure compliance, and drive financial performance for enhanced service delivery and growth i...
4 weeks ago
Director of Quality and Risk - Behavioral Hospital
$80K - $95K *
Contribute to enhancing patient care quality and safety by leading risk management initiatives, ensuring compliance with healthcare standards, and fostering a collaborative environment for staff and p...
1 week ago
CLINICAL MANAGER - INTEGRATED CARE
$135K - $140K *
Lead the transition from hospital to home, ensuring high-quality care and seamless patient experiences. Collaborate with interdisciplinary teams to reduce readmissions and enhance outcomes for partici...
2 weeks ago
Clinical Operations Specialist
$100K *
Lead the charge in enhancing clinical operations across senior living communities, ensuring high standards of care and compliance while traveling extensively throughout Southeast Michigan to support w...
Today
Clinical Operations Specialist
$100K *
Optimize clinical operations across senior living communities, providing guidance and oversight while ensuring quality standards are met. This role requires extensive travel and leadership in a dynami...
Today
$100K - $120K *
Elevate your career by leading surgical services, ensuring optimal patient care, regulatory compliance, and operational efficiency while fostering staff development and clinical excellence in a dynami...
2 weeks ago
$120K - $150K *
Lead a dedicated team to enhance veterinary care, ensuring excellence in patient management and staff collaboration. Drive improvements in medical protocols while fostering a positive work environment...
2 weeks ago
Associate Director of Surgical Services
$110K - $130K *
Unlock potential by providing strategic leadership and operational oversight for perioperative services, enhancing patient care, efficiency, and quality through collaboration with multidisciplinary te...
Yesterday
$100K - $120K *
Elevate your career by leading a dynamic lab team, ensuring quality and compliance while fostering collaboration across disciplines. Drive innovation and excellence in laboratory practices to enhance...
2 days ago
Clinical Director - Private Duty Home Care (RN)
$80K - $95K *
Elevate patient care as you lead clinical operations in a dynamic home care setting. Drive compliance, mentor staff, and enhance quality outcomes while making a meaningful impact on patients and famil...
2 weeks ago
$455K - $475K *
Drive high-quality, patient-focused care in a dynamic health center, overseeing clinical practices and enhancing service delivery while collaborating with teams to achieve health center goals and impr...
1 week ago
Associate Director-Clinical Trials, Submission Data Delivery
$117K - $171K *
Lead the charge in ensuring global consistency of medical data across clinical trials. Drive process improvements and technology strategies while collaborating with cross-functional teams to enhance d...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.