Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$120K - $145K *

Optimize product delivery by leading a team of Product Owners, ensuring that business needs translate into high-quality, scalable solutions. Collaborate with key stakeholders and champion Agile practi...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Advance product strategy by leading a team of Product Owners to deliver scalable solutions. Champion Agile practices and connect business needs with operational objectives in partnership with key stak...

Morrisville, NCRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $170K *

Transform rehabilitation services by leading a dynamic therapy team, driving innovation, and enhancing patient outcomes in a collaborative post-acute environment. Shape the future of therapy with your...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $170K *

Drive excellence in rehabilitation by leading a dynamic therapy team, fostering innovation, and enhancing patient outcomes in a collaborative post-acute care environment...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$187K - $318K *

Lead and optimize oncology pharmacy operations, ensuring safe, effective medication practices and strategic growth across infusion services and investigational drug initiatives...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Lead the charge in overseeing the rehabilitation department, ensuring high-quality services for inpatient and outpatient populations while managing personnel and implementing new treatment programs...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$180K - $220K *

Drive quality medical oversight in a nursing home, guiding staff to deliver optimal patient care while ensuring compliance with medical standards and regulations. Collaborate with healthcare teams to...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Unlock potential by enhancing clinical capabilities and educational outcomes across health centers. Collaborate with nursing leaders to implement standards, mentor staff, and ensure quality care throu...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Lead the operational execution of a patient support program, ensuring high-quality service delivery and compliance. Drive strategic planning, team development, and continuous improvement initiatives t...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform revenue cycle operations by overseeing end-to-end processes, enhancing efficiency, compliance, and financial performance while leading teams to achieve strategic goals and optimize technolog...

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Unlock operational excellence by leading revenue cycle functions, enhancing efficiency from scheduling to payment collection. Drive performance, compliance, and team success while optimizing processes...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in delivering exceptional clinical services by overseeing operations, ensuring compliance, and fostering a culture of excellence in patient care and staff development within a dynamic...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead the delivery of exceptional clinical services, ensuring quality care and regulatory compliance while managing staffing, performance, and continuous improvement for optimal patient outcomes and op...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$267K - $400K *

Empower our commercial legal function by providing strategic legal guidance on pre-launch and market access initiatives. Collaborate across teams to ensure compliance and support successful product la...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$284K - $473K *

Drive the clinical strategy for GU oncology assets, leading cross-functional teams to define and execute innovative development plans, ensuring alignment with regulatory and commercial goals throughou...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$284K - $473K *

Transform clinical development by leading strategic initiatives in oncology GU cancers. Drive asset-level clinical strategy, governance, and decision-making while mentoring talent and leveraging advan...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$183K - $231K *

Advance your career by shaping strategy, partnerships, and investor relations at a key growth stage. Drive critical analyses and collaborate with leadership to propel clinical innovation and value in...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing patient access operations, ensuring compliance and enhancing revenue integrity. Drive strategic initiatives, mentor teams, and collaborate with stakeholders to improve pa...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Unlock your potential by leading clinical services in a supportive environment. Collaborate with a dedicated team to enhance client care and operational efficiency while fostering professional growth...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Lead the charge in managing clinical trial programs, providing operational leadership, and mentoring teams to deliver high-quality data management solutions while fostering client relationships and op...

Markham, ONIn-Person

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $145K *

Elevate your career by managing laboratory and biospecimen operations for clinical studies. Oversee vendor performance, ensure compliance, and mentor team members while driving project success across...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$325K *

Elevate patient care by leading the Care Coordination Model, enhancing throughput and length of stay across hospitals. Drive operational excellence, collaborate with healthcare teams, and ensure compl...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$325K *

Shape the future of patient care by leading our Care Coordination Model, enhancing patient throughput and optimizing hospital operations. Drive strategic initiatives, collaborate with healthcare teams...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $210K *

Champion innovative clinical programming solutions to enhance trial efficiency and data quality. Lead statistical analysis and ensure compliance with regulatory standards while collaborating with cros...

Seattle, WARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.