Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$94K - $130K *

Drive product excellence as a Senior Product Owner, shaping technology solutions in integrated care. Collaborate with agile teams and stakeholders to prioritize needs, enhance workflows, and deliver m...

Kentucky, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Accelerate progress at a leading medical institution by directing clinical trials, enhancing research operations, and mentoring emerging physicians in oncology. Drive innovation and strategic directio...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$73K - $112K *

Elevate surgical services by partnering with leadership to enhance operations, support staff development, and ensure compliance with standards, fostering a patient-centered environment across all peri...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $112K *

Join a team that's dedicated to enhancing surgical services through operational excellence, staff development, and quality improvement. Collaborate with leadership to ensure patient-centered care and...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$140K - $150K *

Join a team that's dedicated to advancing clinical research by managing complex studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficien...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K *

Lead the charge in delivering high-quality, patient-centered care in a dynamic inpatient environment. Oversee clinical operations, guide multidisciplinary teams, and champion initiatives that enhance...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Take ownership of strategic medical leadership in Neurology, driving initiatives to enhance project outcomes. Collaborate with cross-functional teams to ensure compliance and operational excellence in...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion groundbreaking medical initiatives in neurology, guiding project teams and making strategic decisions. Leverage your expertise to ensure compliance and excellence in medical affairs while imp...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion medical affairs initiatives by leading project teams, providing expert neurology guidance, ensuring compliance, and improving patient outcomes through strategic decision-making and operationa...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Lead the charge in overseeing prior authorization operations, ensuring compliance and quality care delivery. Collaborate with clinical teams to enhance policies and workflows while managing a dedicate...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Shape the future of patient care by leading a dynamic team in prior authorization management, ensuring compliance and quality in healthcare delivery while driving program development and operational e...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $135K *

Drive admissions success by cultivating relationships, coordinating referrals, and promoting the facility. Lead tours, process patient intakes, and ensure seamless communication among all stakeholders...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $115K *

Drive admissions success by cultivating relationships and managing referrals. Oversee facility tours and admissions processes, ensuring efficient coordination with healthcare providers and maintaining...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$65K - $100K *

Inspire growth by leading admissions processes and building referral networks. Your role will enhance relationships, foster connections, and ensure seamless coordination between stakeholders in a thri...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Shape the future of biomedical services by overseeing compliance, managing teams, and enhancing operational efficiency. Lead initiatives to improve client satisfaction and ensure the effective mainten...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$220K - $260K *

Champion innovative drug development by leading preclinical R&D efforts. Drive projects from discovery to IND-ready candidates, collaborating with teams and managing external partners to achieve key m...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform the future of Oncology by driving global insights and competitive intelligence. Collaborate with cross-functional teams to influence asset development and strategic decisions, ensuring timel...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to transforming lives through therapeutic support, leading individual and group sessions, and collaborating with families to foster healing and growth in high-risk adolesc...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career by leading academic operations systems that enhance curriculum delivery and assessment. Collaborate with faculty and staff to streamline workflows, ensuring operational efficiency...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$183K - $252K *

Optimize the US medical strategy for nephrology, driving execution and collaboration across teams to enhance patient outcomes through strategic insights, education, and KOL engagement in C3G and IC-MP...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$333K - $450K *

Transform your career by developing innovative clinical strategies and leading Phase 2/3 programs. Collaborate with discovery teams, ensure patient safety, and act as a medical expert while executing...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$333K - $450K *

Optimize clinical development by designing innovative strategies and robust Phase 2/3 programs. Collaborate with discovery teams to lead Phase 1 testing, ensuring patient safety and quality in clinica...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$333K - $450K *

Transform clinical development by creating innovative strategies that enhance efficiency and safety in Phase 2/3 programs while collaborating with discovery teams and ensuring regulatory compliance...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Deliver leadership and governance for global clinical study management, ensuring projects meet timelines and budgets while fostering collaboration and operational excellence across teams and stakehold...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.