Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$179K - $307K *

Join our team as a Clinical Operations Associate Medical Director, enhancing post-acute care management through timely clinical reviews and medical necessity determinations while working flexibly in a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Innovate within Post Acute Care to enhance clinical decision-making, ensuring timely medical reviews. Collaborate with medical teams, maintaining policy consistency and improving patient outcomes in a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Champion clinical excellence by ensuring timely medical reviews and decisions for post-acute care. Collaborate with medical management staff and providers to enhance patient care, utilizing expert kno...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Lead the charge in optimizing post-acute care by ensuring timely clinical decision-making. Collaborate with medical teams to define medical necessity while working flexibly in a supportive virtual env...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Lead the charge in clinical management, ensuring timely decisions for post-acute care services, while supporting the medical management team to enhance outcomes and utilization across various specialt...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Grow your career with a team focused on enhancing post-acute care through effective clinical management. Lead medical decision-making, ensuring high standards of patient care while collaborating with...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Advance your career as a key player in medical management, ensuring timely clinical decision-making and supporting providers in post-acute care settings. Enjoy virtual flexibility while making an impa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Elevate medical management by ensuring timely and accurate clinical case reviews, collaborating with peers for medical necessity assessments, and adhering to established policies to drive efficient ou...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $175K *

Drive operational excellence and strategic growth across diverse healthcare functions, ensuring top-quality care while enhancing financial performance and compliance in a dynamic, physician-led enviro...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Transform psychiatric care delivery by leading outpatient services, providing strategic oversight, ensuring regulatory compliance, and fostering team collaboration to deliver exceptional patient outco...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $400K *

Drive patient care excellence while leading a dynamic dental team. Oversee operations and collaborate with specialists to enhance service offerings, ensuring optimal patient experiences in a thriving...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $400K *

Champion patient care by leading a dynamic dental team, enhancing specialty services, and driving practice growth. Focus on direct patient interactions while managing operations, ensuring optimal dent...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $105K *

Champion high-quality nursing services by managing teams, enhancing care standards, and leading improvement initiatives in skilled facilities while fostering collaboration among staff, residents, and...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$145K - $160K *

Shape exceptional client experiences by leading onboarding and operations. Collaborate with cross-functional teams to manage complex projects, ensuring timely delivery and exceeding client expectation...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $206K *

Unlock the potential of Technical Operations by enhancing business practices, driving data insights, and implementing digital solutions. Collaborate across teams to streamline processes and support st...

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion the delivery of exceptional nursing services by overseeing operations, managing staff, and ensuring compliance with regulations while fostering a collaborative environment to enhance patient...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to delivering exceptional nursing services while overseeing operations and ensuring compliance with regulations. Collaborate with clinical staff to enhance patient care an...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$225K - $250K *

Lead the charge in optimizing healthcare operations across multiple sites, managing a diverse team to enhance profitability and efficiency while fostering strategic relationships with C-suite executiv...

Texas, USRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in transforming clinical strategies into actionable plans, ensuring quality improvement and operational excellence across the organization. Collaborate with executive leadership to dri...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$249K - $330K *

Join a team that's shaping the future of our Encaleret program. Lead strategic planning, enhance operational excellence, and collaborate across functions to guide commercialization. Your insights will...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$249K - $330K *

Elevate strategic planning and operational excellence by leading cross-functional teams to drive the successful commercialization of innovative therapeutics, ensuring alignment and impactful decision...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $125K *

Join us to lead clinical operations and ensure exemplary support for children's developmental needs. Mentor a dedicated team while driving the success of evidence-based programming tailored to each un...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $125K *

Lead the charge in shaping high-quality clinical services for children, mentoring a team of BCBAs and behavior technicians while ensuring evidence-based practices and compliance with standards to fost...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $132K *

Drive strategic revenue growth by leading the billing operations team, optimizing processes, and enhancing cross-functional collaboration. Ensure compliance and efficiency in contracting and credentia...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Drive your career forward by leading a dynamic PMO team, overseeing complex projects in healthcare technology. Collaborate cross-functionally to ensure strategic alignment and successful execution of...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.