Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$100K - $120K *
Transform nursing services through strategic leadership, ensuring compliance, quality improvement, and patient-centered care across all locations while mentoring clinical staff and enhancing operation...
1 week ago
$182K - $198K *
Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...
1 week ago
$168K - $264K *
Drive the development of mechanistic models to guide RNA therapeutic design, collaborating closely with chemists and biologists to enhance siRNA efficacy across various disease programs through advanc...
3 days ago
Director, Project Management - Operations
$120K - $145K *
Transform the future of healthcare operations by leading strategic projects that enhance patient care, optimize processes, and drive revenue growth across multi-site practices. Collaborate with stakeh...
3 weeks ago
Director, Project Management - Operations
$110K - $130K *
Lead strategic initiatives to enhance operational efficiency and patient experience across multi-site healthcare operations. Collaborate with stakeholders to drive measurable improvements in revenue a...
3 weeks ago
Director of Clinical Risk Management
$85K - $100K *
Shape a culture of safety and accountability by leading and enhancing the clinical risk management program, while collaborating with clinical leaders to mitigate risks and improve processes across the...
4 weeks ago
Executive Director Acute Rehabilitation Services
$161K - $235K *
Empower transformative clinical excellence in rehabilitation services, leading a dynamic team to enhance patient care and operational efficiency across multiple facilities while fostering collaboratio...
Today
$180K - $220K *
Transform medical strategies by leading a team of experts, ensuring compliance and scientific accuracy in communications, and fostering client relationships to drive innovative healthcare solutions...
1 week ago
$210K - $250K *
Unlock your potential by leading medical strategies in a dynamic environment. Drive compliance, mentor a talented team, and collaborate with clients to ensure scientific accuracy in promotional materi...
1 week ago
Senior Manager, Virtual Care Operations
$120K - $140K *
Lead and optimize daily operations of a Care Concierge team, ensuring performance meets SLAs while managing staffing, training, and development across a 24/7 environment. Drive efficiency and enhance...
1 week ago
Senior Manager, Virtual Care Operations
$120K - $140K *
Shape the future of healthcare operations by leading a dynamic team, ensuring optimal performance and patient satisfaction across a 24/7 Care Concierge function while driving continuous improvement an...
1 week ago
Senior Director, Care Management
$200K - $320K *
Champion transformative healthcare by leading care management initiatives, enhancing quality and access across services. Collaborate with leadership to optimize operations, improve patient outcomes, a...
Today
Clinical Operations Manager, Nursing
$85K - $100K *
Elevate clinical operations by managing Emergency Department nursing assignments, coordinating staffing, and ensuring quality care across multiple sites. Collaborate with teams to support contract lau...
1 week ago
$80K - $95K *
Join a team that's dedicated to enhancing patient care through effective leadership and operational excellence. Oversee nursing and CMA operations, ensuring quality, safety, and improved health outcom...
2 weeks ago
Director, Clinical AI Research & Evaluation
$186K - $279K *
Drive the scientific foundation for trustworthy clinical AI systems, leading research and evaluation methodologies. Collaborate with cross-functional teams to ensure scalable, regulated practices that...
Today
Associate Director, Strategic Insights
$203K - $247K *
Lead competitive intelligence and strategic insights for immunology initiatives. Collaborate across functions to provide commercial assessments and forecasts, guiding portfolio strategy and executive...
3 weeks ago
Senior Medical Director, Clinical Development
$345K - $375K *
Lead the charge in advancing clinical development for gene-editing therapeutics, focusing on early-stage studies. Collaborate with cross-functional teams to design and execute global trials, ensuring...
2 weeks ago
$80K - $95K *
Join a team that's dedicated to enhancing patient care through effective clinical operations management. Lead staff, optimize workflows, and ensure high-quality service delivery while collaborating wi...
2 days ago
$80K - $95K *
Transform healthcare delivery by leading clinical operations, enhancing workflow efficiency, and driving financial success. Collaborate with senior leadership to ensure high-quality patient care and o...
1 week ago
Senior Manager, Business Operations
$137K - $215K *
Engage with cross-functional teams to lead complex operational initiatives, translating strategic priorities into actionable plans. Drive governance, risk management, and performance monitoring to enh...
3 days ago
Associate Director, Strategic Planning
$110K - $130K *
Join a team that's redefining strategic planning in healthcare. Collaborate with experts to develop innovative, multichannel strategies, driving insights and brand growth while leading diverse project...
2 weeks ago
Associate Director, Strategic Planning
$110K - $130K *
Optimize your career by leading strategic planning initiatives, synthesizing insights, and collaborating with cross-functional teams to drive innovative solutions in the healthcare and pharma sectors...
2 weeks ago
Director of Clinical Reimbursement - MDS/PDPM
$110K - $130K *
Unlock your potential by leading clinical reimbursement and compliance across a multi-site skilled nursing portfolio. Collaborate closely with clinical teams to optimize documentation, reimbursement s...
Reposted 3 weeks ago
$100K - $120K *
Drive operational excellence in physician services by leading recruitment, onboarding, and strategic initiatives. Collaborate with clinical leaders to enhance performance and support decision-making t...
Today
Senior Manager, Quality Program Management
$125K - $150K *
Join a team that's committed to ensuring quality excellence in cell therapy. Oversee integrated project plans, coordinate efforts across departments, and lead initiatives to enhance compliance and ope...
4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.