Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$80K - $95K *

Transform clinic operations by managing staff, finances, and compliance. Collaborate with medical teams to enhance patient care and satisfaction while driving budget development and operational effici...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $141K *

Optimize operational excellence in ambulatory care by leading strategic initiatives, enhancing patient access, and driving financial performance across multiple locations. Collaborate with teams to en...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$137K - $145K *

Elevate your career by leading clinical services in a dynamic environment. Oversee inpatient care, ensure compliance with standards, and foster a culture of excellence while collaborating with diverse...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Advance your career by providing clinical leadership and oversight in skilled nursing and long-term care facilities. Collaborate with interdisciplinary teams to ensure high-quality, patient-centered c...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Join a team that's dedicated to crafting and implementing effective patient support programs. As a strategic leader, you will drive program design, coordinate stakeholder engagement, and ensure succes...

North Carolina, USRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Lead the charge in optimizing resident care by managing nursing services, implementing best practices, and ensuring compliance with standards. Collaborate with a dedicated team to promote quality impr...

Oshawa, ONIn-Person

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $90K *

Drive operational excellence by leading administrative initiatives, enhancing efficiency, and fostering staff development in a dynamic healthcare environment. Collaborate with stakeholders to achieve...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $348K *

Shape your career by providing medical management and support for clinical research projects. Collaborate with teams to ensure compliance, contribute to study design, and mentor staff while driving bu...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Build and manage innovative clinical programs from concept to scale, collaborating with internal teams and external partners. Define workflows, measure outcomes, and create sustainable operating model...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$205K - $307K *

Join a team that's redefining engineering operations by driving performance, accountability, and strategic alignment across engineering, finance, and product. Leverage insights to enhance organization...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$148K - $195K *

Empower global clinical trial delivery through robust stakeholder management, overseeing complex studies from design to report. Foster collaboration, ensure compliance, and optimize operations for suc...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead operational excellence initiatives by collaborating with site leadership to enhance performance, drive continuous improvement, and ensure compliance. Foster a culture of safety and quality while...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive operational excellence by leading a diverse team, enhancing processes, and ensuring high-quality service delivery across multiple healthcare practices while managing regional performance and fos...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$206K - $350K *

Seeking a Medical Director to lead Utilization Management, ensuring evidence-based clinical oversight and compliance. Collaborate with teams to enhance care quality, analyze data to reduce FWA risks...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive clinical excellence as you lead a team of BCBAs and RBTs, overseeing daily operations and ensuring high-quality ABA therapy through collaboration, supervision, and training. Make a meaningful im...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $120K *

Unlock potential by leading a state-of-the-art chiropractic clinic. Drive patient care, manage a dynamic team, and foster community outreach while ensuring exceptional service standards and operationa...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Unlock potential by leading a state-of-the-art chiropractic clinic, driving patient care excellence, and fostering a passionate team environment focused on health and wellness...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Champion administrative excellence by leading multi-team support functions, enhancing service delivery, and driving operational performance. Collaborate with stakeholders to align priorities and foste...

2 days ago

  •   11 - 15 years exp.  •   Business Services

$135K - $160K *

Join a dynamic team as you lead administrative support across multiple offices, ensuring high-quality service delivery, managing talent, and driving operational excellence to meet evolving business ne...

2 days ago

  •   11 - 15 years exp.  •   Business Services

$125K - $150K *

Empower operational excellence by leading administrative support across teams. Drive service delivery, enhance manager effectiveness, and ensure high-quality execution while fostering collaboration an...

2 days ago

  •   11 - 15 years exp.  •   Business Services

$88K - $105K *

Empower clinical excellence by directing and managing comprehensive treatment services for substance use disorders, ensuring compliance and quality across inpatient and outpatient programs while foste...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$152K - $190K *

Lead the charge in establishing a scalable design capability, overseeing design quality, workflows, and resource planning. Collaborate with cross-functional teams to enhance digital experiences while...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$240K - $280K *

Transform your career by leading a dynamic sales team to drive growth and exceed targets in a key regional market. Utilize strategic insights and analytics to optimize performance and ensure complianc...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $210K *

Unlock potential by leading clinical supply chain strategies across multiple global development programs, ensuring investigational products meet patient needs while optimizing resources and compliance...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.