Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$272K - $427K *

Lead the charge in delivering high-quality medical services while enhancing clinical operations and cost-effectiveness. Collaborate with clinicians and stakeholders to drive innovative healthcare solu...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$272K - $427K *

Champion innovative medical services to enhance quality, cost, and outcomes. Lead clinical operations, provide strategic guidance, and develop policies while ensuring effective care delivery and colla...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$272K - $427K *

Lead the administration of medical services, ensuring cost-effective care and quality outcomes. Develop programs, provide clinical consultation, and enhance operations while serving as a resource for...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$272K - $427K *

Oversee the administration of medical services, ensuring cost-effective care. Develop programs to enhance quality and outcomes, provide clinical consultation, and serve as a strategic advisor to impro...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$272K - $427K *

Unlock potential by leading medical services administration to enhance quality, cost, and outcomes. Collaborate with clinicians, develop innovative programs, and serve as a strategic advisor to optimi...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$108K - $179K *

Accelerate progress at our surgical services by leading operational planning and execution for new and expanding procedural services. Collaborate with multidisciplinary teams to drive growth initiativ...

Today

  •   5 - 7 years exp.  •   Healthcare

$181K - $200K *

Champion transformative call center operations by leading strategic outreach, workforce management, and capacity planning. Drive efficiency and quality through innovative automation and AI solutions w...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive operational excellence by leading dental practices, enhancing financial health, and developing talent through effective coaching and compliance management. Collaborate with teams to ensure optim...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $90K *

Lead a dynamic team of clinic managers, driving operational excellence, financial performance, and strategic growth across multiple healthcare facilities to enhance patient care and operational effici...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Lead a dedicated team of case management professionals to enhance patient care coordination, optimize discharge planning, and ensure compliance with clinical standards while driving organizational goa...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Empower your career by leading global regulatory strategies for diverse medical products. Drive compliance and oversee submissions while mentoring a dedicated team in a dynamic, hybrid environment foc...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $176K *

Deliver exceptional patient-centered surgical services by leading staff, ensuring compliance with care standards, and implementing strategies for quality improvements while managing budget and operati...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$242K - $327K *

Unlock commercial potential by leading strategic operations, enhancing processes, and driving cross-functional collaboration to optimize performance and execution across sales, marketing, and field op...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Shape the future of patient care by leading a dedicated team in skilled nursing facilities. Collaborate with Nurse Practitioners to enhance health practices and ensure compliance while providing high...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Elevate healthcare standards by leading quality initiatives and overseeing clinical care in skilled nursing facilities. Collaborate with staff to ensure compliance and deliver patient-centered service...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Transform healthcare delivery by leading skilled nursing facilities as a Medical Director. Collaborate with Nurse Practitioners to enhance patient care, oversee clinical practices, and drive quality i...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Transform healthcare delivery by leading quality initiatives and overseeing clinical care in skilled nursing facilities. Collaborate with staff to ensure compliance and provide comprehensive patient-c...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in promoting health practices as a Medical Director, overseeing clinical care in skilled nursing facilities. Collaborate with staff to enhance quality initiatives and ensure compliance...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Pioneer a transformative approach to healthcare as you lead quality initiatives and collaborate with skilled nursing facilities, ensuring high standards of patient-centered care and compliance with re...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Lead a high-performing consulting team delivering solutions in healthcare technology. Drive commercial performance, enhance delivery quality, and operationalize product transitions while leveraging AI...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Explore innovative AI solutions in healthcare as a strategic leader, guiding product development and technical architecture. Drive large-scale initiatives to enhance clinical and operational excellenc...

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in managing cross-functional clinical drug development projects, ensuring timely execution and alignment with corporate goals while fostering collaboration among diverse teams and exte...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform patient care by leading dialysis operations across multiple facilities. Collaborate with nursing teams to ensure compliance, quality outcomes, and staff development while providing clinical...

Today

  •   Less than 5 years exp.  •   Healthcare

$93K - $232K *

Lead the execution of multi-regional clinical trials, ensuring timely delivery, quality, and compliance. Collaborate with cross-functional teams and sponsors to drive project success and foster strong...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $232K *

Drive the execution of multi-regional clinical trials, ensuring timely delivery, quality, and compliance. Collaborate with cross-functional teams and sponsors to manage project scope, budgets, and ris...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.