Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Senior Director, Head of Pharmacovigilance Operations
$288K - $325K *
Elevate pharmacovigilance operations by leading strategy, team development, and compliance. Oversee ICSR management, vendor relations, and inspection readiness while driving process improvements and e...
2 weeks ago
Nursing Director (RN) Main Operating Room
$120K - $238K *
Optimize nursing leadership by fostering a collaborative, patient-centered environment. Drive operational excellence and enhance care delivery standards across units, ensuring a safe and supportive at...
3 weeks ago
Clinical Director for Residential Facility
$80K - $95K *
Manage and oversee clinical services, ensuring quality and compliance. Collaborate with leadership on program development and staff training while providing clinical supervision. Drive operational exc...
Reposted 2 weeks ago
$80K - $95K *
Inspire and shape clinical excellence as you lead ABA teams, ensuring integrity, developing leaders, and enhancing client outcomes through strategic oversight and collaboration in a supportive environ...
Reposted 1 week ago
$110K - $130K *
Develop high-performing teams and drive operational excellence in a mobile diagnostics operation. This role offers extensive freedom and responsibility, preparing you for impactful leadership as a loc...
Yesterday
$86K - $130K *
Transform strategic operations across multiple clinical divisions, driving program growth and enhancing service delivery. Lead initiatives for regional expansion and multi-site management while ensuri...
1 week ago
Program Manager, Care Operations
$95K - $115K *
Drive the execution and scaling of AI-enabled cardiovascular care programs, collaborating across teams to enhance workflows and operational efficiency while ensuring continuous improvement in patient...
1 week ago
Associate Director, Clinical Supply Chain
$186K - $233K *
Optimize clinical supply chain operations by planning and delivering compliant clinical supplies while collaborating with cross-functional teams to support ongoing development programs in a dynamic ph...
1 month ago
Senior Director, Digital Marketing
$175K - $210K *
Shape the future of healthcare by leading digital growth marketing initiatives, optimizing enterprise demand generation, and driving strategic marketing operations to enhance revenue insights and oper...
Reposted yesterday
Associate Director, Business Operations
$117K - $156K *
Unlock operational excellence by leading strategic initiatives and fostering collaboration across laboratory functions. Drive efficient service delivery to enhance client satisfaction and support sust...
1 month ago
Director Ambulatory Operations - OB/GYN - Center City
$110K - $130K *
Champion operational excellence by overseeing clinical and business activities across multiple OB/GYN offices. Collaborate on strategic planning, optimize staffing, and enhance patient experience whil...
Yesterday
Director of Practice Operations Vascular Surgery
$97K - $180K *
Transform healthcare operations by overseeing provider management, optimizing workflows, and enhancing patient safety. Collaborate with teams to drive financial growth and ensure compliance while fost...
Today
Associate Director, Commercial Operations
$165K - $225K *
Shape the future of commercial operations by driving strategic partnerships, managing contract negotiations, and ensuring seamless integration of manufacturing and business teams in the biopharmaceuti...
2 weeks ago
Director, Field Medical Director/ MSL Field Director- Pain
$160K - $200K *
Innovate the future of Field Medical leadership by establishing a robust MSL organization, engaging KOLs, and driving strategic initiatives to support product launches and scientific exchange in pain...
1 week ago
Medical Director, Clinical Development (Neurology)
$248K - $341K *
Provide clinical development leadership for multiple programs, enhancing communication and collaboration across functions. Contribute to strategy, oversee trials, present findings, and mentor team mem...
3 weeks ago
Medical Director, Clinical Development (Neurology)
$248K - $341K *
Lead clinical development initiatives across multiple studies, driving collaboration and innovative strategies. Shape and execute clinical trial objectives while fostering relationships with key stake...
3 weeks ago
$80K - $95K *
Transform operations in a dynamic OBGYN department by leading a dedicated team, ensuring quality patient care, and enhancing service delivery through effective management and collaboration with health...
2 weeks ago
Medical Director - Admissions & Urgent Care
$280K - $350K *
Shape the future of behavioral health by leading Admissions and Psychiatric Urgent Care services. Oversee clinical operations, ensure quality care, and mentor a dedicated team while enhancing patient...
Yesterday
Medical Director - Admissions & Urgent Care
$280K - $350K *
Join a team that's dedicated to enhancing behavioral health services through clinical leadership and operational excellence. Drive quality care and strategic development in psychiatric urgent care and...
Yesterday
Director, Clinical Science – Oncology Clinical Development
$189K - $316K *
Elevate cancer care by providing scientific leadership in oncology clinical development. Collaborate with cross-functional teams to ensure data integrity and robust interpretation, driving impactful c...
6 days ago
Director, Clinical Science – Oncology Clinical Development
$189K - $316K *
Drive scientific leadership in oncology clinical development, ensuring robust study design, data integrity, and regulatory compliance. Collaborate with cross-functional teams to enhance clinical outco...
6 days ago
Senior Director, Clinical Science
$260K - $330K *
Drive strategic clinical science initiatives in oncology, leading cross-functional teams to enhance study design and execution. Collaborate on data integration and recommendations to advance clinical...
2 weeks ago
$247K - $427K *
Lead the administration of medical services, ensuring quality care for millions. Collaborate with clients to enhance clinical operations and drive innovative solutions in a virtual environment, while...
3 days ago
$247K - $427K *
Shape the future of healthcare by leading medical services, ensuring quality care, and driving innovative programs for cost-effective solutions across a vast client base. Collaborate with clinical tea...
3 days ago
Associate Director, Clinical Supply Chain
$180K - $212K *
Drive comprehensive clinical supply activities, including demand planning, inventory optimization, risk mitigation, and cross-functional collaboration to ensure alignment with clinical objectives and...
Reposted 4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.