Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$108K - $130K *

Lead nursing operations to enhance patient care, optimize staffing, and ensure compliance with regulatory standards. Collaborate with directors to streamline processes and improve efficiency across de...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join us to lead clinical excellence and enhance patient care across departments. Drive strategic initiatives, manage interdisciplinary teams, and ensure compliance with standards while fostering a cul...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Explore a rewarding role overseeing clinic operations, leading teams, and ensuring exceptional patient care in a dynamic healthcare environment. Drive compliance, financial management, and quality ass...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Drive the success of our clinic by leading operations, enhancing patient care, managing finances, and ensuring compliance while inspiring your dedicated team to deliver outstanding service and quality...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$80K - $95K *

Lead clinic operations by managing staff, enhancing patient care, and ensuring compliance. Deliver financial oversight, inventory control, and quality assurance while driving patient engagement and te...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$190K - $250K *

Unlock your potential by delivering strategic communications advice in the Healthcare sector. Lead teams, engage stakeholders, and drive business development while fostering a collaborative environmen...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Elevate your career as a Clinical Director, leading surgical operations and collaborating with healthcare professionals to ensure excellence in patient care and facility management. Enjoy a supportive...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$164K - $190K *

Drive clinical development strategies by leading study design, execution, and oversight. Collaborate cross-functionally to ensure compliance and optimize clinical outcomes for both marketed and pipeli...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$238K - $315K *

Reimagine clinical trial safety leadership by establishing scalable operations and governance. Collaborate across teams to ensure data quality and compliance while driving innovation in patient safety...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$170K - $303K *

Drive innovative product development programs through effective leadership and strategic management, overseeing all phases from conception to market launch while ensuring cross-functional collaboratio...

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$171K - $214K *

Transform your career by driving strategic alignment and execution within the Medical function. Collaborate with senior leaders to translate priorities into action, enhance organizational effectivenes...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Transform the operations of an opiate treatment center by overseeing daily activities, ensuring compliance, and enhancing team performance while delivering exceptional patient care and service...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower your career by leading Therapy Operations, shaping patient care, and driving quality standards. Collaborate with teams to enhance community health while utilizing advanced technology and foste...

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading Therapy Operations, shaping patient care, and fostering community health. Drive strategic initiatives, ensure compliance, and enhance team performance while delivering high...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $179K *

Join us to oversee daily operations, enhance staff education, ensure compliance, and manage fiscal responsibilities within assigned departments, fostering a culture of excellence in patient care and t...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead operations to enhance patient care and ensure compliance with regulations. Drive financial success and growth through strategic planning and active involvement in sales and marketing. Collaborate...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$158K - $216K *

Champion data management excellence by overseeing vendor contracts, ensuring data quality, and supporting commercial teams. Collaborate cross-functionally to resolve data issues and drive strategic in...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $200K *

Lead a dynamic veterinary hospital, driving operational excellence and financial sustainability. Inspire teams, foster innovation, and ensure exceptional patient care while managing a $60M+ P&L in a c...

2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$140K - $150K *

Shape your career by managing clinical research studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficiently and effectively...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$270K - $310K *

Drive strategic leadership in patient safety sciences, overseeing activities, fostering collaboration, and building a high-performing team to enhance safety measures across oncology clinical trials an...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$270K - $310K *

Drive patient safety excellence by leading strategic oversight and development of safety sciences, fostering collaboration across teams, and shaping innovative drug safety practices to enhance clinica...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$179K - $238K *

Empower clinical excellence by leading operations, education, and supply chain initiatives. Collaborate with executive leadership to standardize practices, enhance patient safety, and drive quality ou...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$254K - $347K *

Champion program management excellence by leading cross-functional teams, driving project strategies, and ensuring timely delivery of milestones in a dynamic pharmaceutical environment. Foster collabo...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $240K *

Join a dynamic clinical leadership team to coach and develop providers while delivering direct patient care in senior living communities, ensuring high-quality clinical performance and fostering commu...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.