Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$140K *

Drive revenue growth as you lead a dynamic team of Account Managers, ensuring portfolio health and strategic expansion within a diverse range of customers. Your leadership will facilitate disciplined...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$195K - $256K *

Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$195K - $256K *

Champion the North America Clinical Quality Assurance strategy, overseeing audits, inspections, and compliance with regulations. Lead a team to ensure adherence to Good Clinical Practice and enhance q...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $130K *

Reimagine operations by leading our packaging and kitting teams to double revenue while enhancing quality and delivery. Drive continuous improvement and develop talent to create meaningful work experi...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $130K *

Grow your career with a transformative operations leadership role focused on scaling packaging and kitting operations while enhancing quality and delivery. Lead a dedicated team to drive meaningful ch...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $130K *

Transform operations by scaling packaging from $5M to $10M while enhancing quality and delivery. Lead a dedicated team, optimize ERP systems, and create meaningful work experiences for individuals wit...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $130K *

Lead our operations team to scale packaging and kitting from $5M to $10M, enhancing quality and delivery. Drive continuous improvement and optimize our ERP system while fostering meaningful work exper...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$157K - $231K *

Elevate clinical technology strategy and operations by leading cross-functional teams. Shape AI-driven solutions, manage resources to meet objectives, and influence business areas in achieving strateg...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $136K *

Optimize operational leadership and financial management for home health care centers, ensuring quality patient care, regulatory compliance, and staff development while driving business growth and per...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Champion exceptional patient care by leading clinic operations, fostering a supportive team, and enhancing efficiency. Drive financial performance and community engagement while ensuring compliance an...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive clinical excellence by overseeing program execution, staff training, and compliance. Collaborate with leadership to enhance patient care and ensure adherence to standards while fostering a cultu...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Transform operations at our community clinic by leading a dedicated team, ensuring efficient patient care, managing fiscal responsibilities, and fostering staff development while upholding high standa...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$82K - $98K *

Join a team that's dedicated to advancing medical strategies through innovative solutions. Collaborate with experts to enhance scientific communication and drive impactful healthcare initiatives, ensu...

2 days ago

  •   Less than 5 years exp.  •   Media

$180K - $236K *

Accelerate progress at the intersection of operations and strategy, driving cross-functional excellence and optimizing processes to enhance provider operations and experience. Collaborate with leaders...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Shape the future of healthcare by leading specialty services across multiple states, enhancing provider teams, and improving patient outcomes through strategic clinical initiatives and operational exc...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$170K - $190K *

Elevate clinical trial execution by providing strategic oversight and operational leadership. Collaborate cross-functionally to ensure studies meet quality, budget, and regulatory standards while driv...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $173K *

Accelerate your career by leading quality operations in clinical trials. Collaborate with cross-functional teams to embed quality-by-design principles and ensure inspection readiness, driving operatio...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion the fight against addiction by leading a dedicated team, providing clinical oversight, and delivering compassionate care to individuals facing substance use disorders. Your expertise will dri...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in providing clinical oversight and support for addiction treatment, ensuring comprehensive care for patients with complex substance use disorders while collaborating with a dedicated...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$143K - $173K *

Transform clinical quality operations by embedding quality-by-design principles and ensuring inspection readiness across clinical programs, while collaborating with cross-functional teams to drive ope...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$244K - $305K *

Drive the financial and operational strategy for global clinical development, overseeing budgeting, resource planning, and vendor management. Lead a team to ensure timely study delivery while managing...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$170K - $215K *

Engage in building and managing commercial operations infrastructure to enhance sales execution. This role focuses on analytics, reporting, pricing support, and training, ensuring data-driven insights...

Today

  •   8 - 10 years exp.  •   Healthcare

$170K - $215K *

Advance commercial operations by building robust reporting, analytics, and governance frameworks. Drive sales execution through strategic pricing, SFDC management, and actionable insights, ensuring da...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Empower a dynamic team to lead global clinical supply chain operations, ensuring seamless execution from First-in-Human to late-stage development. Drive strategic initiatives, foster cross-functional...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$201K - $360K *

Help us redefine patient safety by leading pharmacovigilance efforts and collaborating with cross-functional teams to ensure high-quality medical evaluations throughout the product lifecycle. Your exp...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.