Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$115K - $120K *

Architect clinical operations ensuring effective programming, staff management, and compliance. Oversee client care, implement evidence-based practices, and lead a multi-disciplinary team to enhance t...

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform laboratory operations by leading teams to achieve safety, quality, and efficiency goals. Drive performance management, regulatory compliance, and talent development while fostering cross-fun...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...

Boston, MARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Oversee and optimize clinical trial operations, ensuring timely execution and compliance across global studies. Collaborate with cross-functional teams and vendors to manage budgets, timelines, and ri...

Vancouver, BCIn-Person

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Lead the charge in managing complex clinical trials, ensuring timely execution, budget adherence, and compliance with regulations. Collaborate with cross-functional teams and vendors to drive operatio...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Transform clinical trial management by overseeing operations, budgets, and timelines. Collaborate with cross-functional teams and vendors to ensure compliance and timely delivery of trials, contributi...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion the development of clinical operations by managing a network of providers, establishing policies, and enhancing quality programs. Collaborate with leadership to ensure operational excellence...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform patient care by leading a dedicated clinical team, enhancing operational efficiency, and ensuring compliance with healthcare standards while fostering a culture of excellence and collaborati...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion clinical excellence by leading a dedicated care team, enhancing patient satisfaction, and ensuring compliance with healthcare standards while driving operational efficiency and team engagemen...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform healthcare delivery by leading clinical operations and enhancing team performance. Drive patient satisfaction and compliance while managing a dedicated care team to ensure quality services f...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Champion the delivery of exceptional clinical care by leading a dedicated team, ensuring compliance with standards, and enhancing patient satisfaction. Drive operational excellence and foster a collab...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K *

Transform your career by leading clinical operations and program development. Oversee staff, ensure compliance with health standards, and enhance client treatment experiences in a dynamic environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Shape the future of laboratory information management by leading high-quality LIMS implementations for public health and environmental laboratories, ensuring stakeholder alignment and project success...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Manage and execute complex LIMS implementations for public health and environmental labs. Collaborate with cross-functional teams to ensure project success, stakeholder alignment, and high-quality out...

Tucson, AZRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$238K - $315K *

Lead global postmarketing safety operations, driving excellence in case management and external engagement. Collaborate with cross-functional teams to enhance operational performance and support the c...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$87K *

Shape the future of youth mental health by leading therapy programs, supervising staff, and ensuring quality care in a supportive environment. Drive impactful change while fostering professional growt...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$194K - $253K *

Elevate quality standards by leading GxP compliance initiatives across R&D. Collaborate with cross-functional teams to ensure adherence to regulations, conduct audits, and drive a culture of continuou...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$194K - $253K *

Reimagine your career by leading GxP Quality Assurance efforts, ensuring compliance across R&D. Collaborate with cross-functional teams to uphold industry standards and drive a culture of quality thro...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$233K - $267K *

Drive strategic initiatives as a senior leader in Clinical Practice Liaison, shaping team vision and performance. Collaborate with cross-functional teams to enhance medical strategy and ensure complia...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Optimize customer engagement by designing connected experiences that bridge strategy and execution. Lead cross-functional teams to ensure seamless journey mapping, activation, and continuous improveme...

CanadaRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$186K - $233K *

Join a team that's transforming clinical data management by leading data strategy and ensuring the integrity of trial data. Collaborate with cross-functional teams and external vendors to support the...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Advance your career by providing strategic leadership in oncology and hematology research operations. Oversee clinical trials, ensure regulatory compliance, and collaborate with physician leaders to e...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$111K - $178K *

Champion operational excellence by leading clinic practices, enhancing quality, and fostering collaboration among stakeholders to drive effective healthcare delivery across multiple regions...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$151K - $268K *

Lead the charge in enhancing customer experience by advocating for service excellence, collaborating across departments, and driving strategic initiatives to elevate patient and healthcare professiona...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $285K *

Champion the integration and advancement of Advanced Practice Providers, ensuring their voices shape organizational decisions while enhancing professional development and optimizing care delivery acro...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.