Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director, CMC Operations
$155K - $190K *
Manage the planning and execution of CMC operations across multiple development programs, ensuring alignment with regulatory milestones and efficient collaboration with cross-functional teams and CDMO...
3 days ago
Associate Director RN Clinical Care Operations
$95K - $115K *
Grow your career with a leadership role overseeing diverse clinical teams, enhancing patient care, and driving operational excellence in a dynamic healthcare environment. Collaborate with nursing lead...
Today
Senior Manager, Clinical Programs
$145K - $175K *
Advance clinical trial execution globally by leading a team of managers, ensuring compliance and achieving milestones in diagnostics and medical devices. Collaborate cross-functionally to enhance oper...
3 days ago
Senior Director, Physician Experience: CareerMD
$146K - $282K *
Join a team that's redefining physician engagement by building lasting relationships and managing a vast network of career events. Lead strategic initiatives to enhance provider experiences and drive...
Reposted today
Senior Director, Physician Experience: CareerMD
$146K - $282K *
Join us in enhancing physician relationships and engagement through strategic leadership, managing a dynamic team, and executing impactful career events that foster lifelong partnerships with healthca...
Reposted today
$90K - $215K *
Lead creative operations to optimize digital media campaigns, ensuring efficiency and quality. Foster team development, strengthen client partnerships, and implement scalable processes to enhance coll...
3 days ago
$120K - $168K *
Elevate your career by leading clinical studies from planning to execution. Collaborate with cross-functional teams to ensure compliance, quality, and timely delivery of study objectives while managin...
2 days ago
$108K - $167K *
Join a team that's dedicated to enhancing patient care through clinical leadership and operational excellence. Drive quality improvement initiatives and support compliance across multiple bases while...
4 days ago
Regional Director, Clinical & Regulatory Support, Post Acute Services
$110K - $130K *
Lead initiatives to enhance clinical services in post-acute care, driving quality improvements and operational efficiency while collaborating with multidisciplinary teams to ensure optimal patient out...
6 days ago
Director, Business Development
$120K - $150K *
Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...
Reposted 1 week ago
Director Clinical - Ophthalmology
$110K - $130K *
Accelerate clinic operations by leading teams, managing budgets, and driving change. Foster an inclusive environment while ensuring high-quality service delivery and continuous improvement in a tertia...
3 days ago
Medical Director - Orange, San Diego & Ventura County
$210K - $250K *
Drive meaningful change by leading clinical services for substance use programs across multiple counties. Collaborate with a dynamic team, oversee patient care, and foster professional growth while en...
3 weeks ago
$115K - $120K *
Architect clinical operations ensuring effective programming, staff management, and compliance. Oversee client care, implement evidence-based practices, and lead a multi-disciplinary team to enhance t...
1 month ago
Associate Director, Lab Operations
$110K - $130K *
Transform laboratory operations by leading teams to achieve safety, quality, and efficiency goals. Drive performance management, regulatory compliance, and talent development while fostering cross-fun...
Yesterday
$180K - $195K *
Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...
2 weeks ago
$180K - $195K *
Oversee and optimize clinical trial operations, ensuring timely execution and compliance across global studies. Collaborate with cross-functional teams and vendors to manage budgets, timelines, and ri...
2 weeks ago
$180K - $195K *
Lead the charge in managing complex clinical trials, ensuring timely execution, budget adherence, and compliance with regulations. Collaborate with cross-functional teams and vendors to drive operatio...
2 weeks ago
$180K - $195K *
Transform clinical trial management by overseeing operations, budgets, and timelines. Collaborate with cross-functional teams and vendors to ensure compliance and timely delivery of trials, contributi...
2 weeks ago
Area Director Clinical Ops & Engagement
$100K - $120K *
Transform patient care by leading a dedicated clinical team, enhancing operational efficiency, and ensuring compliance with healthcare standards while fostering a culture of excellence and collaborati...
6 days ago
Area Director Clinical Ops & Engagement
$100K - $120K *
Champion clinical excellence by leading a dedicated care team, enhancing patient satisfaction, and ensuring compliance with healthcare standards while driving operational efficiency and team engagemen...
6 days ago
Area Director Clinical Ops & Engagement
$110K - $130K *
Transform healthcare delivery by leading clinical operations and enhancing team performance. Drive patient satisfaction and compliance while managing a dedicated care team to ensure quality services f...
6 days ago
Area Director Clinical Ops & Engagement
$100K - $120K *
Champion the delivery of exceptional clinical care by leading a dedicated team, ensuring compliance with standards, and enhancing patient satisfaction. Drive operational excellence and foster a collab...
2 weeks ago
$100K *
Transform your career by leading clinical operations and program development. Oversee staff, ensure compliance with health standards, and enhance client treatment experiences in a dynamic environment...
1 week ago
$80K - $100K *
Shape the future of laboratory information management by leading high-quality LIMS implementations for public health and environmental laboratories, ensuring stakeholder alignment and project success...
Reposted 2 weeks ago
$80K - $100K *
Manage and execute complex LIMS implementations for public health and environmental labs. Collaborate with cross-functional teams to ensure project success, stakeholder alignment, and high-quality out...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.