Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Manage delivery leadership for life sciences CRM transformation programs, ensuring high-quality implementations and migrations. Collaborate with cross-functional teams to meet client expectations and...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K *

Oversee a dynamic team to execute media strategies, optimize campaigns, and ensure resource alignment with business goals, driving performance and compliance across various advertising channels...

New York, NYRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$75K - $100K *

Join a team that's dedicated to enhancing client satisfaction and profitability. As a key player, you'll manage client relationships, support sales processes, and ensure seamless communication between...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's redefining oncology care by overseeing clinical standards, evaluating therapies, and engaging with providers. You'll play a key role in shaping patient eligibility and treatment pro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $175K *

Lead global clinical trials, manage cross-functional teams, and ensure project success across multiple therapeutic areas while driving operational excellence and best practices in clinical project man...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Staffing

$150K - $180K *

Join a dynamic team to drive operational excellence across Business Units, ensuring accurate forecasting, insightful reporting, and effective execution. Collaborate closely with GMs to enhance perform...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $135K *

Join us to lead and enhance healthcare staffing operations, driving growth and performance through strategic recruitment, client management, and team leadership. Collaborate across departments to achi...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$130K - $170K *

Partner with us to enhance consultant relationships in healthcare. Drive business growth by cultivating partnerships, optimizing engagement strategies, and aligning internal teams to effectively posit...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead new business initiatives across the Central and Eastern U.S. by managing complex enterprise sales cycles in healthcare technology, driving growth through strategic partnerships and collaboration...

Boston, MARemote

Reposted today

  •   5 - 7 years exp.  •   Staffing

$112K - $193K *

Lead the charge in transforming pharmacy prior authorization operations, overseeing a large team to enhance quality, compliance, and financial performance while driving innovation and process improvem...

Eden Prairie, MNRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$215K - $408K *

Join a dynamic team to lead medical management and quality improvement initiatives, ensuring optimal care delivery and cost-effectiveness while collaborating with clinical teams and providers to enhan...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$165K - $175K *

Champion strategic people initiatives by advising leadership, crafting executive communications, and leveraging analytics to drive organizational effectiveness and accountability across the People fun...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $240K *

Elevate healthcare impact by building and scaling enterprise accounts in women's health. Own the sales cycle, engage stakeholders, and drive screening initiatives while collaborating across teams to e...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $160K *

Join a team that's dedicated to transforming behavioral health operations by implementing strategic initiatives, ensuring quality standards, and enhancing support for clinic leaders. Collaborate acros...

Boulder, CORemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$133K - $180K *

Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$177K - $266K *

Strategize and lead regional sales initiatives, driving growth and profitability. Oversee a management team, develop business plans, and negotiate contracts while ensuring alignment with organizationa...

North Carolina, USRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$98K - $147K *

Empower success by leading strategic programs that enhance clinical, financial, and operational outcomes. Collaborate with teams to optimize processes and ensure alignment with organizational goals, d...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in driving client success by building trusted partnerships, understanding client objectives, and ensuring seamless delivery of services. Collaborate with internal teams to enhance sati...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$255K - $348K *

Champion a high-performing field sales organization to drive sustainable growth across specialty therapeutic areas. Inspire accountability and resilience while enhancing patient outcomes through strat...

California, USRemote

Reposted 1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Join us to lead Oncology integrated solutions, collaborating across teams to design and implement strategic, client-focused approaches. Shape impactful proposals that drive growth and enhance patient...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Transform customer success by leading a high-performing post-sales organization. Drive retention, adoption, and measurable ROI while scaling operations and building strong relationships with key healt...

San Francisco, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $201K *

Lead the charge in shaping and evolving a global web ecosystem, overseeing strategy, operations, and governance to deliver high-performing digital experiences that drive engagement and business growth...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to enhancing patient care through telephonic evaluations and assessments. Collaborate with stakeholders to improve protocols and outcomes while ensuring timely patient int...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.