Mississippi hosts an array of high-paying professional jobs across several industries. When you are looking for a job that pays over $100,000 in Mississippi, Ladders is your best resource. We host only vetted positions that offer lucrative salaries in the sector you're interested in.
With its diverse economy and steady job growth, Mississippi is an ideal place to escalate your career. The state offers improved work-life balance, and residents also enjoy a lower cost of living compared to other states. In addition to the scenic charm, Mississippi offers a growing professional ecosystem where talent and determination are rewarded.
Take the first step towards your dream job by exploring our extensive listing of high-paying jobs in Mississippi. Our job descriptions are comprehensive and include the skills and qualifications needed for each position, making it easier for you to find the right fit.
$115K - $140K *
Support accurate financial reporting and compliance as you oversee accounting operations, collaborate with various teams, and drive process improvements in a remote environment, ensuring adherence to...
1 week ago
$120K - $140K *
Strategize and build innovative customer success systems, leading a dynamic team to enhance client retention and growth. Shape operational models while actively managing key accounts in a mission-driv...
Reposted 6 days ago
Executive Director, Agentic Lab and Architecture Lead
$225K - $418K *
Innovate enterprise-wide agentic AI solutions by leading architecture design, guiding prototyping, and establishing robust standards for scalable, responsible deployments. Shape future technologies wh...
3 weeks ago
$78K - $88K *
Champion the future of audiovisual design by delivering innovative systems and high-quality documentation across diverse projects. Collaborate with multidisciplinary teams to ensure effective project...
3 weeks ago
Regional Clinical Study Manager
$118K - $158K *
Innovate clinical operations by leading regional study delivery to ensure compliance, quality, and timely execution. Collaborate effectively with external partners and stakeholders while managing budg...
Reposted 4 weeks ago
Senior Full-Stack Security/GRC Platform Engineer
$86K - $129K *
Innovate your career by maintaining and extending a full-stack Governance, Risk, and Compliance platform. Collaborate across backend and frontend systems focusing on security, compliance mapping, and...
Reposted 1 week ago
Senior Director, Biostatistics
$223K - $302K *
Lead strategic biostatistical efforts in biosimilar development, managing teams and overseeing projects while ensuring high standards of quality, innovation, and regulatory compliance. Drive excellenc...
Yesterday
$80K - $95K *
Lead the charge in optimizing accounts payable processes, ensuring accurate invoice processing, timely vendor payments, and compliance. Manage a dynamic team while driving process improvements to enha...
1 month ago
VP, Security Technology (Deputy CISO)
$220K - $311K *
Join and lead the enterprise security program, focusing on client needs, product security, and growth initiatives. Partner with executives to translate security strategies into operational success whi...
Today
$73K - $165K *
Advance analytics by designing and implementing end-to-end data solutions across Core products, ensuring seamless integration and delivery of actionable insights through data visualization and managem...
2 weeks ago
Chief of Staff - Commercial Strategy
$180K - $220K *
Shape the future of healthcare by driving growth initiatives and strategic alignment across teams. Collaborate with executives to enhance market positioning, lead cross-functional projects, and transl...
3 weeks ago
Senior Analyst, Customer Success Operations
$99K - $110K *
Lead the transformation of Customer Success Operations, using your expertise to enhance reporting, drive strategic initiatives, and collaborate cross-functionally. This role requires analytical skills...
Reposted 3 weeks ago
$60K - $103K *
Join a team that pioneers impactful training solutions, enhancing the employee experience through innovative curriculum design. Utilize your instructional design expertise to create effective learning...
2 weeks ago
Senior or Principal Technical Product Manager
$165K - $245K *
Drive the development of technically sound products by collaborating with cross-functional teams. Shape product capabilities, prioritize work, and bridge business and technical needs to deliver comple...
2 weeks ago
Director, Channel Partnerships, Health Systems
$150K - $180K *
Advance strategic partnerships with health systems by driving growth, expanding services, and fostering collaboration. Lead a high-performing team to enhance referrals across a comprehensive wellness...
2 weeks ago
Senior Business Analyst (Consumer and Merchant Analytics)
$100K - $129K *
Accelerate progress at a growing company by transforming data into strategic insights, enhancing sales efficiency with automated reporting, and driving data-driven improvements across teams to support...
2 weeks ago
$120K - $145K *
Shape the future of financial solutions by leading a high-performing SAP FICO team, delivering strategic initiatives, and driving innovation in SAP implementations while aligning with organizational o...
Reposted 5 days ago
Elastic Security Education & Enablement Consultant
$100K - $115K *
Join a team that's dedicated to empowering customers with Elastic Security training and support. You'll lead training efforts, develop curriculum, and enhance security operations by translating comple...
Yesterday
Medicaid Payment Integrity SME
$110K - $140K *
Champion program integrity by leading Medicaid audits, investigations, and risk assessments, ensuring compliance while collaborating with teams to enhance payment accuracy and provider oversight. Flex...
3 weeks ago
Lead, Clinical Research Associate - US
$100K - $120K *
Lead and empower a team of Clinical Research Associates to oversee and enhance site management activities for clinical trials, ensuring compliance and quality in project execution while fostering prof...
3 weeks ago
$85K - $141K *
Transform healthcare outcomes by designing and implementing AI solutions that enhance operational efficiency, streamline processes, and support data-driven decision-making across the organization. Lea...
Reposted 3 weeks ago
$120K *
Support key cybersecurity compliance initiatives, including CMMC certification. Collaborate with teams to develop and maintain security documentation, conduct assessments, and ensure adherence to regu...
Reposted yesterday
Chief Executive Officer (CEO), Physical AI and Spatial Intelligence, Founding Team, Remote
$150K - $250K *
Strong candidates have sold into VP and C-level buyers across operations, supply chain, IT, and asset management, often inside the same deal, and have built a commercial motion from zero...
5 days ago
RCM Sr Manager Client Executive
$84K - $117K *
Build strong client relationships while managing service interactions and driving resolution for client escalations. Lead cross-functional teams to deliver quality outcomes, ensuring adherence to KPIs...
3 weeks ago
Senior Manager, AI Transformation & Process Excellence
$113K - $178K *
Pioneer enterprise transformation by harnessing Lean Six Sigma, AI, and automation to enhance operational performance, drive innovation, and deliver measurable value across multiple business functions...
Yesterday
What industries in Mississippi offer high-paying jobs?
Mississippi has high-paying jobs in several industries like Healthcare, Education, Manufacturing, IT, and more. Most of these jobs require professional degrees and experience in specific fields.
What are the benefits of finding a job in Mississippi?
In addition to a lower cost of living, Mississippi provides opportunities to work in evolving industries with competitive salaries. The state also offers a great work-life balance and a thriving community.
Why should I use Ladders to find a job in Mississippi?
Ladders is a trustworthy source for job seekers. We offer an extensive listing of high-paying jobs that are vetted and offer salaries over $100,000. Our job descriptions are detailed, ensuring you can find the perfect fit for your skills and qualifications.