Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$170K - $190K *

Champion strategic leadership in nonprofit operations, ensuring alignment with mission and values. Oversee diverse ministries, foster partnerships, and drive program growth while maintaining financial...

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$220K - $250K *

Unlock strategic opportunities in patient advocacy and engagement. Drive impactful initiatives for Systemic Mastocytosis while collaborating across teams to uplift patient voices and foster partnershi...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Transform quality assurance and improvement activities across regional and local structures, ensuring collaboration with operational leaders and key advisory bodies to achieve strategic quality goals...

Victoria, BCIn-Person

Reposted 4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$101K - $146K *

Lead the operations of medical groups, ensuring financial and quality goals are met. Collaborate with hospital administration to enhance provider engagement and oversee staffing, recruitment, and cont...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $150K *

Shape your career by managing clinical research studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficiently and effectively...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive the integration of point-of-care testing and lab information systems, ensuring compliance and operational efficiency. Collaborate with clinical staff to enhance patient care through effective ma...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to delivering compassionate care while overseeing daily operations, ensuring staff efficiency, and fostering a risk-free environment for patients in a dynamic healthcare s...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Lead the charge in nursing excellence by overseeing standards and practices, ensuring quality patient care, and collaborating with hospital leadership to enhance services and staffing in a dynamic hea...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $325K *

Lead the charge in advancing clinical AI and care delivery systems, guiding a high-performing engineering team to innovate solutions that streamline clinician workflows and enhance patient care throug...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $325K *

Join a cutting-edge healthcare tech team to lead engineering in AI and clinical systems. Drive innovation by managing teams, optimizing workflows, and collaborating across functions to transform care...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Lead the hospital's strategic vision and operations, ensuring high-quality care and community engagement. Drive business development, resource management, and quality improvement initiatives while fos...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $110K *

Join a team that's dedicated to delivering high-quality, patient-centered care while leading nursing operations in a dynamic Medical Surgical Trauma unit, ensuring optimal outcomes and fostering a col...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Drive high-quality, patient-centered care as a Clinical Nurse Coordinator, overseeing unit operations, mentoring staff, and ensuring optimal patient outcomes in a collaborative environment focused on...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$195K - $341K *

Engage in clinical oversight and support staff training while ensuring adherence to quality standards and regulatory compliance in a collaborative healthcare environment focused on member care and ope...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Manage and optimize partnerships with Community Health Centers, ensuring alignment on clinical, operational, and financial goals while delivering exceptional patient outcomes through strategic oversig...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Shape the future of healthcare quality by overseeing process improvement and ensuring patient safety across multiple departments. Collaborate with stakeholders to evaluate programs and implement evide...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's pivotal in supporting executive leadership through complex scheduling, travel arrangements, and project execution. Your proactive approach will enhance organizational efficiency and...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $223K *

Champion strategic initiatives in healthcare by leading the Surgery Program, driving innovation, optimizing care, and fostering collaboration among diverse teams to achieve impactful outcomes and enha...

Edmonton, ABIn-Person

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$156K - $234K *

Shape the future of medical staff governance by leading operational oversight and compliance initiatives. Collaborate with key stakeholders to enhance credentialing processes and ensure effective mana...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$79K - $127K *

Help us drive efficiencies in physician preference item management, foster relationships, and maintain compliance across our Neurosurgical and Orthopedic services while achieving significant savings g...

Pennsylvania, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform your career by leading clinical teams to enhance patient care, ensuring operational excellence and compliance. Drive quality initiatives while fostering a collaborative environment that prio...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead clinical operations and staff development to ensure high-quality patient care. Oversee daily functions, drive compliance, and implement safety initiatives while fostering a collaborative environm...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead the charge in transforming educational services by overseeing operations, financial strategies, and compliance in a dynamic academic environment. Collaborate with senior leadership to enhance par...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$92K - $100K *

Transform patient care by collaborating with providers for effective health management, education, and clinical protocols, ensuring top-notch patient experiences and health outcomes in a dynamic clini...

1 month ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$115K - $145K *

Transform integration solutions by leading a skilled team to deliver seamless application interfaces and interoperability across diverse customer environments, ensuring quality and efficiency in proje...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.