Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Lead and enhance clinical operations in an assisted living community by ensuring quality care, compliance with regulations, and fostering team development, while managing resident health assessments a...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$333K - $450K *

Lead the charge in innovative clinical programs, shaping strategies and executing trials from first-in-human to registration, while ensuring patient safety and compliance in a dynamic regulatory envir...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$94K - $120K *

Lead the charge in providing clinical leadership and program management, ensuring high-quality patient care outcomes through development and execution of strategic plans, policies, and performance man...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Empower women’s health initiatives by overseeing comprehensive medical services in a correctional facility. Collaborate closely with diverse healthcare providers to deliver evidence-based care and sup...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Transform healthcare delivery by overseeing comprehensive medical services for women, ensuring high standards of care for marginalized populations, coordinating with specialists, and leading quality i...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Empower impactful philanthropy by leading fundraising strategies across two foundations, fostering crucial relationships with donors and stakeholders to align with community needs and enhance philanth...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Transform data capabilities by building foundational systems and a high-performing team. Drive analytics, reporting, and production systems while ensuring data integrity and strategic alignment with b...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive operational excellence by leading the Performance Improvement team, aligning departmental goals with strategic priorities, and fostering a culture of continuous improvement across the organizati...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$300K - $310K *

Lead clinical excellence by combining patient care with physician leadership, enhancing outcomes and performance in a value-based care model while supporting primary care providers across the market...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Drive strategic leadership in clinical and nursing research operations, enhancing evidence-based practices and fostering collaboration across interdisciplinary teams to improve patient and organizatio...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion operational excellence by leading nursing strategies that enhance patient care, optimize staffing, and improve throughput. Collaborate with diverse teams to implement evidence-based practices...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $140K *

Shape the future of care transitions by leading high-quality, integrated home healthcare. Collaborate with interdisciplinary teams to improve outcomes and reduce readmissions, ensuring participants re...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $140K *

Lead the transition from hospital to home, ensuring high-quality care and seamless patient experiences. Collaborate with interdisciplinary teams to reduce readmissions and enhance outcomes for partici...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $140K *

Lead the charge in enhancing patient care transitions from hospital to home. Collaborate with interdisciplinary teams to ensure high-quality, individualized care, reducing readmissions and improving h...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead strategic initiatives and operational excellence as the chief executive, ensuring high-quality care and fiscal integrity while fostering community partnerships and collaboration with stakeholders...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Reimagine healthcare delivery by leading a dedicated team in long-term care. Enjoy flexibility and growth while providing exceptional medical oversight and support in skilled nursing facilities. Make...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Elevate operational excellence by leading enterprise-wide initiatives, ensuring scalable processes, and driving financial performance. Collaborate with executives to enhance customer delivery and fost...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Innovate clinical services by leading a dedicated team to enhance patient care, ensuring compliance with standards and regulations while fostering collaboration with multidisciplinary professionals an...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Lead the charge in enhancing patient care by overseeing Social Services operations, ensuring compliance, and fostering collaboration among multidisciplinary teams to deliver exceptional behavioral hea...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Unlock potential by leading the development of a multi-specialty clinic, enhancing clinical efficiency, financial viability, and staff performance while ensuring a patient-centered focus and complianc...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $95K *

Optimize clinical research operations by leading a team of coordinators, ensuring protocol compliance, data integrity, and regulatory readiness while mentoring staff and managing study timelines effec...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Join our team to lead clinical research operations, ensuring protocol compliance and data integrity while mentoring coordinators and managing study activities from start to finish...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Join a dynamic team as you lead clinical research operations, ensuring protocol compliance and data integrity while mentoring coordinators and managing study logistics from start to finish...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $225K *

Champion exceptional member experiences by leading operations and care teams. Design scalable systems that ensure consistent quality across all interactions, driving efficiency and accountability in a...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.