Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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1,000+

Anesthesiologist Jobs in Oklahoma

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$232K - $290K *

Shape the future of global People Operations by leading innovative HR service delivery, enhancing employee experiences, and driving operational excellence in a rapidly scaling biopharmaceutical enviro...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $185K *

Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$212K - $233K *

Advance your career by overseeing regional nursing operations, ensuring compliance, quality care, and staff development. Collaborate with multidisciplinary teams to enhance patient services and suppor...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $138K *

Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive analytical solutions by leading projects, applying advanced data analysis, and collaborating with clients to deliver actionable insights across energy initiatives including efficiency and sustai...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$97K - $145K *

Lead strategic client coding integration initiatives, ensuring alignment with corporate objectives and regulatory compliance while driving operational excellence and innovation across the revenue cycl...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Engage with a talented team to drive growth and innovation in pharma sales. Own the sales cycle from strategic prospecting to closing high-impact deals, while developing key relationships that enhance...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $157K *

Optimize data-driven strategies by transforming raw analytics into actionable insights. Collaborate with cross-functional teams to enhance marketplace dynamics and drive measurable business outcomes i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$120K *

Transform mental health care by building strategic partnerships with providers to enhance access to specialized OCD treatment. Drive growth through relationship-building, education, and effective refe...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $167K *

Transform clinical account management by leading strategic initiatives, enhancing client relationships, and driving operational excellence. Collaborate with cross-functional teams to achieve business...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $195K *

Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$192K - $235K *

Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $244K *

Unlock your potential as a Global Regulatory Leader, driving regulatory strategy and submissions for CNS projects. Collaborate with cross-functional teams, mentor junior staff, and ensure compliance w...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Transform patient care by developing tailored treatment plans and enhancing mobility. Collaborate with a dynamic team, leveraging mentorship and professional growth opportunities in a supportive envir...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate your career by focusing on endodontic care in a collaborative environment. Enjoy clinical autonomy while benefiting from an established patient base and modern technology, all within a customi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Empower your career by driving commercial success as you engage healthcare providers, build relationships, and support innovative therapies in a dynamic, remote role focused on impactful patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $156K *

Transform the product marketing landscape by executing strategic go-to-market plans, ensuring cohesive messaging across athenaOne offerings. Collaborate with cross-functional teams to drive market und...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $110K *

Join a team that's dedicated to enhancing compliance and operational integrity through thorough audits and evaluations, ensuring adherence to regulations while fostering a culture of continuous improv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $149K *

Join a dynamic team in evaluating medication prior authorizations while developing clinical criteria and working closely with healthcare providers to ensure quality patient care through evidence-based...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$135K - $160K *

Innovate by leading the architectural transformation of a legacy platform into a scalable, AI-driven solution. Your expertise will guide modernization efforts while enhancing performance and security...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$64K - $96K *

Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving BioPharma partnership success through innovative liquid biopsy solutions, enhancing clinical trial designs, and fostering key relationships in oncology precision medicine...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Drive growth in digital therapeutics by engaging medical practices, guiding them from initial interest to consistent orders. Collaborate with sales and clinical teams to shape the onboarding process a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.