Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$80K - $85K *

Pioneer in claims management by analyzing complex auto bodily injury claims, ensuring timely resolutions while adhering to industry standards and client expectations. Collaborate with vendors and stak...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in driving transformative growth by cultivating strategic relationships and delivering on sales targets within a dynamic healthcare environment, ensuring sustained profitability and ma...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $166K *

Lead the charge in managing site contract negotiations and agreements, ensuring alignment with clinical study timelines. Collaborate with cross-functional teams to enhance contract processes and mento...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving sales strategy and value analysis, partnering with cross-functional teams to enhance proposals, pricing, and contracts. Lead market research and client engagement to optimi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in strategic pre-award contracting, driving compliance and operational excellence. Oversee a high-performing team while collaborating across functions to enhance efficiency and support...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$113K - $188K *

Unlock potential by leading product strategy and management for diverse lines, ensuring customer needs drive innovation while aligning with corporate goals. Collaborate with cross-functional teams to...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$145K - $190K *

Join a team dedicated to advancing oncology clinical trials. In this role, you’ll manage global studies, oversee vendors, collaborate with multi-disciplinary teams, and ensure compliance with regulato...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $132K *

Champion the design of agent-ready workflows by translating complex business processes into clear requirements. Collaborate with product teams to enhance AI capabilities and ensure seamless human-agen...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's redefining healthcare recruiting by building and scaling a high-impact Direct Employer business through innovative sales strategies and cutting-edge technology, driving growth direc...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$143K - $193K *

Transform clinical operations by leading regional study delivery, ensuring quality and compliance while managing timelines and budgets. Collaborate with cross-functional teams to drive study success a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $185K *

Join a team that's transforming customer experiences through innovative technical solutions. As a Solutions Architect, you'll bridge business needs with technology, guiding clients from discovery to d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Shape the future of clinical documentation integrity by leading audits and compliance initiatives across facilities. Collaborate with healthcare teams to enhance operational efficiency and ensure adhe...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$78K - $113K *

Join us to lead the Professional Coding Operations team, ensuring accurate coding practices and compliance. Collaborate with stakeholders, mentor staff, and drive improvements in coding efficiency and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$82K - $150K *

Join a team that's driving growth in the dental implant market by aggressively prospecting and converting new customers. Leverage your sales expertise to expand market share and position value-oriente...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share within the dental implant community. Leverage a hunter mentality to convert competitive accounts and position value-ori...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage a hunter mentality to convert competitive accounts and position value-oriented s...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $225K *

Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$140K - $210K *

Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Take ownership of complex institutional partnerships, driving customer success and retention. Collaborate cross-functionally to enhance account growth, manage contracts, and optimize platform implemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$105K - $140K *

Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.