Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$90K - $110K *

Advance your career by delivering critical cost estimates for federal programs. Collaborate with a dynamic team to enhance national security through effective budgeting and analysis of advanced commun...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$164K - $305K *

Lead the charge in developing strategic relationships with C-suite executives to drive growth, retention, and value realization across complex health systems, ensuring integrated solutions and measura...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $85K *

Shape the future of patient care by leading an outpatient therapy team. Collaborate with staff to enhance service delivery and drive business growth while preparing for advancement to center manager...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Elevate our Enterprise business by building impactful relationships with brokers and consultants. Drive engagement strategies, generate new business opportunities, and enhance BetterHelp's presence in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $230K *

Join a dynamic team as you manage oncology product promotions, build relationships with key stakeholders, and drive brand value through strategic engagement and innovative solutions in a competitive b...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$192K - $240K *

Unlock your potential as a Product + Design Strategist, leading ambiguous projects from concept to execution. Collaborate with cross-functional teams to create innovative, user-centered experiences an...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to ensuring safe and effective radiation therapy delivery. Collaborate with oncologists and clinical staff to uphold treatment accuracy, regulatory compliance, and patient...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $290K *

Join a team that's shaping innovative brand strategies for rare epilepsy programs. Lead marketing initiatives, drive launch readiness, and build a high-performing team to deliver impactful solutions f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Empower the Foot and Ankle team by driving growth and building key relationships. Engage with surgeons in the operating room and support sales initiatives to enhance product adoption and customer sati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $300K *

Build strategic relationships with scientific leaders to drive innovation in Pulmonary Hypertension. Engage in scientific exchange, support research initiatives, and enhance understanding of therapeut...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Explore your career by building strategic partnerships in the life sciences sector. Drive account growth, develop client relationships, and connect with key stakeholders to enhance business opportunit...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$175K - $230K *

Empower healthcare innovation by leading a team of Field Clinical Specialists. Drive the successful launch of the Globe Pulsed Field System through training, support, and relationship-building with he...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing contract management and customer experience. Leverage your expertise in contract administration and customer service to streamline processes and ensure compli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the market presence of Chorus by owning positioning, messaging, and launch governance. Collaborate with cross-functional teams to craft strategies that enhance product perception and drive insig...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$208K - $235K *

Join a dynamic team to architect scalable cloud solutions, ensuring high engineering standards while collaborating with cross-functional stakeholders to drive innovation and governance in a fast-paced...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$152K - $283K *

Deliver impactful field execution by bridging strategy and operations, ensuring initiatives achieve success through proactive risk management and collaboration across teams, all while enhancing accoun...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $195K *

Unlock patient engagement strategies by integrating insights into drug development. Collaborate with diverse teams to generate evidence, engage with professional societies, and lead initiatives that p...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Unlock potential by designing secure, enterprise-scale solutions that protect critical data and systems. Collaborate with stakeholders to assess threats, innovate security architecture, and enhance en...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Optimize the promotional review process by coordinating cross-functional workflows, ensuring compliance, and facilitating timely approvals of marketing materials. Collaborate with internal and externa...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Shape user experiences by designing intuitive UI for Playground and Console. Collaborate with senior designers on impactful feature work, enhancing product impressions while gaining fluency in our des...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $250K *

Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$79K - $96K *

Unlock potential by delivering compassionate nursing care, ensuring quality and adherence to individual care plans while collaborating with a dedicated clinical team in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Elevate your career by leading multiple dialysis centers, driving operational excellence, and fostering a culture of patient care. Collaborate with a dedicated team to achieve strategic growth and ens...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $215K *

Lead the charge in brand strategy, inspiring teams and fostering innovative solutions in a dynamic healthcare advertising environment, focused on advancing compelling communications and effective clie...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.