Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$80K - $100K *

Lead a dynamic team in delivering high-quality veterinary care while fostering professional growth and collaboration. Enjoy a supportive environment with modern resources and opportunities for mentors...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Join a team that's redefining software engineering by integrating AI tools to accelerate the development process. Transform requirements into reliable solutions while ensuring quality, security, and m...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $171K *

Unlock potential by driving data-driven insights for Customer Success. Collaborate across teams to enhance customer journeys, optimize growth strategies, and shape analytics foundations that support A...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$208K - $250K *

Unlock your potential by joining a thriving multi-specialty clinic, collaborating with a diverse team to deliver quality patient care and utilizing a robust referral network in a collegial, supportive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Inspire excellence in patient care at a leading multi-specialty clinic, where you'll collaborate with a dynamic team of healthcare professionals to enhance services and drive better outcomes in a supp...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's dedicated to exceptional patient care and outcomes. Work alongside a large, collaborative group of physicians in a supportive environment that prioritizes your growth and offers com...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Join a team that's redefining internal medicine, collaborating with a skilled group of professionals to deliver high-quality patient care across multiple locations in a supportive, family-friendly atm...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$208K - $250K *

Contribute to a leading multi-specialty clinic by delivering high-quality care as an Internal Medicine Physician. Collaborate with a diverse team to provide excellent patient outcomes in a supportive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Join a team that's redefining internal medicine with a collaborative, patient-centric approach. Engage with diverse cases, foster professional growth, and enjoy a family-friendly environment in a lead...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$173K - $245K *

Unlock insights through data analytics and experimentation to enhance credit risk management. Collaborate with cross-functional teams to optimize policies, monitor performance, and drive strategic gro...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Champion the future of post-acute care by leading a dynamic team, ensuring high-quality patient services, and driving operational excellence across your region. Collaborate with interdisciplinary team...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $217K *

Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $100K *

Drive your career forward by managing key partnerships and delivering measurable results. This role blends strategic relationship management with consultative selling, ensuring partner success and gro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Transform regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $134K *

Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $180K *

Champion the use of innovative medical technology by training and supporting clinical staff in the effective application of the Globe PF System, ensuring successful clinical trials and enhancing patie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $197K *

Transform the landscape of AI by architecting and optimizing cutting-edge LLMs while collaborating with diverse tech teams to innovate and enhance applications for performance and accuracy in resource...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$70K - $100K *

Join a team that's dedicated to optimizing Epic Resolute Professional Billing. Support daily operations, troubleshoot issues, and enhance workflows while collaborating with analysts and users to ensur...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$166K - $244K *

Join a dynamic team to lead the Employer PMO, driving strategic program delivery and cross-functional alignment while enhancing operational efficiency and leveraging modern tools for impactful outcome...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a team that's dedicated to identifying and recruiting top-tier leadership talent across various sectors. Engage in full-cycle recruiting or selected stages, leveraging your expertise to connect w...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$200K - $215K *

Advance the cloud platform capabilities, ensuring secure, reliable, and scalable product delivery while enhancing developer experience and shaping reliability practices in a mission-driven healthcare...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Empower our provider team's mission by designing innovative tools for therapists. You'll create streamlined solutions that enhance patient care, drive efficiency, and leverage technology while collabo...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders, promoting innovative products, and exceeding performance goals in a dynamic biopharma environment. Collaborate effec...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.