Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$85K - $113K *
Unlock the potential of reinsurance accounting by ensuring accurate reporting and analysis. Collaborate with cross-functional teams to enhance processes, maintain compliance, and support financial int...
2 weeks ago
Partners in Performance - Performance Strategy Principal Director
$293K - $429K *
Drive impactful business strategies in the Resources industry, guiding clients through complex challenges. Leverage your expertise to influence C-Suite decisions and foster long-term partnerships whil...
4 days ago
Partners in Performance - Performance Strategy Principal Director
$300K - $357K *
Join a team that's redefining business strategy in the Resources industry. Leverage your expertise to guide clients through complex challenges, driving impactful decisions at the C-suite level while m...
6 days ago
$220K - $260K *
Elevate the buying experience by leading product strategy, enhancing catalog quality, and optimizing marketplace economics. Drive measurable outcomes through collaboration with operations and engineer...
3 weeks ago
Senior Technical Product Owner - Investments
$126K - $188K *
Transform your career by leading strategic product planning and managing complex investment solutions. Collaborate with stakeholders to define product vision, oversee project delivery, and drive innov...
1 week ago
Senior Manager, Global Deal Desk
$125K - $150K *
Champion scalable deal operations by leading the Global Deal Desk, optimizing complex agreements across sales, finance, and legal. Drive AI integration to enhance workflows and ensure compliance while...
2 weeks ago
$211K - $272K *
Transform your career by leading enterprise applications strategy and delivery. Collaborate with cross-functional teams to enhance processes, drive AI adoption, and ensure robust application architect...
Reposted today
$150K - $180K *
Unlock potential by leading client relationships and driving strategic measurement initiatives. Manage a diverse portfolio, ensuring retention and growth while guiding teams to deliver impactful marke...
Reposted 4 days ago
$75K - $112K *
Unlock potential by managing complex billing processes and leading a team to ensure accurate invoicing and exceptional customer service. Collaborate across departments to drive efficiency and implemen...
1 week ago
$80K - $95K *
Join a team that's driving strategic litigation projects, managing budgets, and providing expert consultation. Oversee complex cases, collaborate with clients, and ensure efficient service delivery wh...
4 weeks ago
Associate Director, Operational Excellence
$110K - $130K *
Lead operational excellence initiatives by collaborating with site leadership to enhance performance, drive continuous improvement, and ensure compliance. Foster a culture of safety and quality while...
4 weeks ago
Senior Project Manager, Campaign Operations
$180K - $200K *
Manage the campaign calendar and ensure timely launches by transforming customer requests into actionable specs. Collaborate with cross-functional teams to maintain project alignment and drive success...
2 weeks ago
Associate Director, Enterprise Information Architecture
$143K - $193K *
Accelerate progress at the forefront of data-driven transformation in life sciences. Collaborate with leadership to shape and execute enterprise data architecture initiatives, ensuring scalable, trust...
3 weeks ago
Strategic Account Executive, Named Accounts (Remote, US)
$110K - $130K *
Drive your career forward by managing strategic enterprise accounts, fostering relationships, and identifying growth opportunities. Leverage your sales expertise to navigate complex cycles and collabo...
5 days ago
$80K - $95K *
Engage with mission-driven organizations to drive growth in housing solutions. Own the full sales lifecycle, from prospecting to closing, while expanding your portfolio and collaborating across teams...
1 week ago
Sr. Account Executive , Amazon Leo
$142K - $193K *
Drive enterprise growth by managing complex accounts and executing strategic sales initiatives. Collaborate cross-functionally to deliver customer-centric solutions and achieve measurable business out...
1 week ago
Content Management and Operations Lead (Drupal)
$110K - $155K *
Lead content operations for a federal web services program, managing a team to ensure timely, accurate, and accessible communication. Drive strategic planning, oversee Drupal content management, and e...
Reposted 6 days ago
$125K - $150K *
Unlock potential by leading financial planning and analysis for site operations, collaborating with cross-functional teams, and driving strategic initiatives to enhance business success and operationa...
Reposted 2 weeks ago
$80K - $95K *
Unlock potential by managing month-end and year-end closes, ensuring accurate financial reporting across multiple entities. Collaborate with cross-functional teams to streamline processes and enhance...
2 weeks ago
Group Project Manager, Healthcare and Pharmaceutical Advertising
$120K - $150K *
Champion integrated project management for complex pharmaceutical advertising, leading cross-functional teams to ensure timely delivery within scope and budget while mentoring junior staff and enhanci...
1 week ago
$130K - $160K *
Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...
Reposted 6 days ago
Account Executive (HCM, Payroll, Saas, Healthcare)
$76K - $102K *
Engage in a dynamic role driving client acquisition in the Home-Based Care sector. You'll build a robust pipeline, execute sales strategies, and collaborate cross-functionally to enhance client experi...
3 weeks ago
$150K - $180K *
Champion growth by developing and executing territory plans to maximize revenue. Collaborate with sales, marketing, and business development teams to drive results and enhance market share through eff...
5 days ago
$105K - $131K *
Lead the charge in expanding our civil government business in Texas. Develop strategies, build relationships, and drive growth by navigating government agencies and closing large-scale contracts. Make...
Yesterday
Vice President, Capital & Investments (Real Estate)
$200K - $300K *
Elevate your career by leading investment strategies and capital allocation for a dynamic enterprise. Collaborate with senior leadership to drive portfolio performance and ensure alignment with long-t...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.