Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr Program Manager, Client Delivery
$155K - $180K *
Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...
Reposted today
$125K - $150K *
Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...
4 days ago
Area Sales Director, Southwest
$415K - $435K *
Empower your career by leading regional Enterprise sales strategies to drive business growth and expand market presence. Manage high-performing teams and build relationships with C-suite executives to...
Reposted 2 weeks ago
$142K - $168K *
Transform client experiences by leveraging deep expertise in healthcare solutions. Lead strategic initiatives, enhance client relationships, and drive impactful outcomes for high-value accounts throug...
1 week ago
$83K - $138K *
Join our team as a Senior Revenue Accountant to enhance global revenue assurance, ensuring compliance with ASC 606 while collaborating with cross-functional teams to drive operational consistency and...
4 days ago
$86K - $108K *
Optimize financial integrity as a Senior Accountant, managing general ledger functions, supporting month-end closes, and collaborating cross-functionally to ensure accurate reporting in a dynamic, hig...
Yesterday
Associate Director, Omnichannel Marketing - Prostate Cancer
$170K - $213K *
Transform customer engagement by leading omnichannel marketing strategies, collaborating with cross-functional teams, and leveraging data insights to enhance HCP and patient experiences in the pharmac...
1 week ago
Enterprise Account Executive, East
$250K - $300K *
Execute innovative strategies to acquire and expand client relationships, leveraging expertise in AI/ML solutions. Be a proactive networker, navigating complex sales cycles to foster business growth a...
Reposted 4 days ago
Customer Success Director (Oracle Focused)
$100K - $125K *
Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...
Reposted today
Director Underwriting - Remote
$124K - $211K *
Transform your career by leading underwriting teams, driving pricing strategies, and ensuring financial performance. Collaborate across departments to influence business growth and deliver sustainable...
2 weeks ago
Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)
$79K - $139K *
Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...
1 week ago
Associate Medical Director, Global Safety Physician
$184K - $253K *
Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...
5 days ago
Sr Account Manager, Industrial Water, NA
$120K - $140K *
Partner with us to drive growth in industrial accounts, leveraging your sales expertise to expand relationships and deliver innovative water treatment solutions that meet the needs of our customers an...
Reposted 1 week ago
Senior Director Business Operations
$168K - $240K *
Lead the charge in optimizing business operations through innovative solutions, driving efficiency and productivity while fostering cross-functional collaboration and data-driven decision-making to en...
1 week ago
$80K - $95K *
Join a team that's dedicated to expanding healthcare partnerships by identifying and nurturing relationships with hospitals. Drive innovative consignment solutions while collaborating with internal te...
5 days ago
Lead Accountant - Investment Reporting
$103K - $136K *
Join a dynamic team as you lead investment accounting and reporting efforts, ensuring accuracy and compliance. Collaborate across departments to enhance financial processes and drive improvements in a...
3 weeks ago
Implementation Manager, Financial Services
$100K - $120K *
Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...
5 days ago
Senior Director, Strategic Growth
$150K - $180K *
Drive strategic growth by leading business development and sales operations, optimizing RFP processes, and enhancing performance metrics. Collaborate across teams to ensure alignment and improve outco...
Yesterday
Director, Managed Services-Voice & Services
$116K - $145K *
Elevate operational excellence by leading technical escalation and onboarding teams in Managed Services. Drive high-quality service delivery across voice, SD-WAN, and security, ensuring seamless custo...
1 week ago
Director, Managed Services-Voice & Services
$116K - $145K *
Join a team that's redefining managed services by leading technical escalations and customer onboarding for voice services. Drive operational excellence and ensure high-quality service delivery across...
1 week ago
Account Manager, Client Development & Renewals (East Coast / Mid-Atlantic)
$123K - $135K *
Engage in a growth-focused role managing existing accounts, driving renewals and expansion. Collaborate with teams to identify opportunities, ensure customer satisfaction, and achieve revenue goals wh...
1 week ago
Account Executive Retail - US Countrywide
$90K - $110K *
Grow your career with a dynamic role focused on sales success and account management. Drive profitable solutions in the retail sector while fostering long-lasting customer relationships and delivering...
Reposted 2 weeks ago
Account Manager, Life Sciences
$100K - $120K *
Transform client relationships by driving retention and growth in a dynamic SaaS environment. Collaborate with diverse stakeholders to maximize product adoption and uncover new opportunities, ensuring...
4 weeks ago
$120K - $150K *
Lead the charge in building long-term customer relationships while optimizing operations. As a Business Manager, you'll drive strategic growth, manage key accounts, and collaborate across teams to enh...
1 week ago
Senior Commercial Lines Producer
$100K - $120K *
Engage with business leaders to develop a profitable commercial insurance book. Leverage relationships and resources to create new opportunities, expand client accounts, and establish yourself as a tr...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.