Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Sales Director - Life Science
$120K - $230K *
Unlock potential by driving strategic sales in the Life Sciences sector. Engage with key stakeholders, shape IT solutions, and achieve ambitious growth targets while leveraging your extensive network...
3 weeks ago
Vice President, Client Services
$160K - $200K *
Lead the charge in strategic client services management, overseeing growth, engagement, and high-value account portfolio. Drive team performance and build enduring client relationships that enhance bu...
Reposted 2 weeks ago
Account Manager, CoCounsel Legal
$136K - $253K *
Champion customer success by leading the migration of SMB accounts to CoCounsel, driving engagement and adoption through consultative selling and strategic outreach. Collaborate with teams to ensure s...
3 days ago
$110K - $130K *
Optimize our product suite to elevate financial advisory capabilities through innovative AI solutions. Lead the entire product lifecycle, collaborating with diverse teams to transform complex workflow...
Reposted 3 days ago
Commercial Account Manager - Small Commercial
$81K - $91K *
Contribute to client success by managing policy applications, renewals, and coverage inquiries. Collaborate with producers to ensure timely service and maintain strong client relationships while stayi...
4 weeks ago
Mid-Market Account Executive - Public Sector
$152K - $190K *
Shape the future of IoT by driving complex sales to mid-sized customers, forging impactful relationships, and leading the charge in the digital transformation of essential industries. Enjoy a fully re...
Reposted 2 days ago
Regional Director Of Operations
$100K - $120K *
Transform operations by leading regional facilities, ensuring quality care, compliance, and financial performance while developing strong leaders and fostering a positive workplace culture...
1 week ago
$127K - $187K *
Join a team that's driving growth by building strategic partnerships with K-12 education leaders. This role focuses on managing a regional portfolio, executing sales strategies, and presenting innovat...
1 week ago
Sr. Director, Retrieval Operations (Call Center & Workforce Operations)
$181K - $200K *
Champion transformative call center operations by leading strategic outreach, workforce management, and capacity planning. Drive efficiency and quality through innovative automation and AI solutions w...
1 week ago
$95K - $105K *
Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...
6 days ago
$130K *
Shape the future of telecommunications by leading complex, large-scale projects. Drive strategic planning, manage executive communications, and ensure program success through innovative solutions and...
2 days ago
Director, RevOps Strategy & Operations
$150K - $180K *
Drive operational excellence by leading revenue operations strategy, optimizing processes, and enhancing cross-functional alignment to support scalable growth and measurable outcomes in a dynamic envi...
Yesterday
Associate Director Of Brand Activation & Content
$120K - $145K *
Lead the charge in defining and activating brand strategies across multiple channels, enhancing donor engagement and retention through innovative content and social communications while collaborating...
1 week ago
$150K - $180K *
Lead the charge in global quality strategy for high-speed interconnect solutions, driving operational excellence and customer satisfaction. Collaborate across teams to ensure top-tier product quality...
1 week ago
Commerce Media Strategist, Amazon DSP (Full Funnel)
$80K - $95K *
Elevate client success by crafting and optimizing innovative commerce media strategies. Leverage data-driven insights to enhance campaign performance across platforms, ensuring measurable growth and c...
1 week ago
$80K - $100K *
Accelerate business growth by owning the full sales cycle and expanding strategic partnerships with enterprise retailers. Leverage insights to consistently exceed revenue targets and drive impactful s...
Reposted 3 weeks ago
Director of Channel Partnership Development
$125K - $140K *
Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...
1 week ago
Director, Sustainability Regulatory Advisory
$200K - $230K *
Shape the future of sustainability advisory by leading complex engagements, driving business growth, and delivering high-quality regulatory compliance solutions in a rapidly evolving ESG landscape...
1 week ago
Audit & Tax Marketing Director
$184K - $276K *
Elevate brand visibility and revenue growth by leading strategic marketing initiatives for Audit and Tax practices. Collaborate with leadership to execute compelling campaigns that enhance client enga...
2 weeks ago
Audit & Tax Marketing Director
$184K - $276K *
Join a dynamic team as you shape and execute innovative marketing strategies for Audit and Tax practices. Drive brand visibility and client engagement in a fast-paced environment, leveraging your stra...
2 weeks ago
Key Account Leader, Majors, Public Safety (Northwest)
$144K - $180K *
Transform public safety through strategic account leadership, driving sales for drone technology in major agencies. Own the full sales cycle, build deep relationships, and leverage AI tools to enhance...
5 days ago
Director, Data Solutions & Engineering
$150K - $180K *
Join a team that's redefining data solutions by leading the Data Products & Engineering department, shaping cutting-edge data architectures and innovative client-facing analytics solutions that drive...
Reposted yesterday
$90K - $110K *
Lead the charge in optimizing business processes and technology solutions, serving as the primary liaison between stakeholders and technical teams to enhance operational efficiency and customer experi...
2 weeks ago
Senior Sales Executive, Strategic Banking
$130K - $160K *
Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...
4 days ago
$132K - $155K *
Unlock potential by providing advanced technical support and solutions, ensuring exceptional customer experiences. Collaborate with teams to resolve issues, mentor peers, and drive product improvement...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.