Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$91K - $115K *

Transform the candidate experience by sourcing top talent for sales and corporate roles. Collaborate with recruiters and hiring managers to build pipelines, utilizing advanced sourcing techniques and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive impactful AI and Agentforce delivery projects, managing customer relationships and internal initiatives. Leverage your strategic planning and analytical skills to oversee project execution and f...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$210K - $260K *

Elevate IT operations by leading system integration and security strategy. Own the full tech stack, streamline processes, and enhance patient care through automation and effective team management in a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize patient access workflows by aligning registration with revenue cycle needs. Collaborate with stakeholders to enhance eligibility processes and improve patient estimates, while mentoring IS st...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $260K *

Transform the workplace culture and integration of two organizations, ensuring support for clinicians and staff while enhancing benefits, compensation, and recruitment strategies to foster a unified m...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $176K *

Transform downstream marketing for cutting-edge medical devices. Drive product launches, develop compelling content, analyze market trends, and ensure regulatory compliance across global regions while...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $130K *

Unlock potential by guiding complex power system studies for mission critical facilities. Collaborate with designers, manage projects independently, and leverage advanced technologies to enhance opera...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Accelerate growth by leading global partnerships with PwC and GSIs. Drive revenue through strategic relationship management, co-selling initiatives, and market expansion while collaborating with cross...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $200K *

Lead the charge in transforming business challenges into innovative solutions by leveraging your expertise in automation and integration. Collaborate across teams to enhance operational efficiency and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $185K *

Join a team that's redefining finance analytics by leading strategic forecasting and performance management. Drive impactful financial insights and methodologies while collaborating with leadership to...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$96K - $135K *

Elevate your career as a strategic leader in paid social, driving growth through innovative strategies and high-performing teams. Leverage your expertise to optimize complex campaigns and foster colla...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$98K - $126K *

Empower customer success by managing renewals, driving growth, and mitigating risks. Collaborate with cross-functional teams to enhance client relationships and ensure satisfaction while maximizing co...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$85K - $100K *

Join a team that's dedicated to delivering exceptional indirect tax solutions. You'll manage compliance, conduct research, and collaborate with clients across multiple jurisdictions, enhancing their t...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$79K - $107K *

Join a team that's redefining energy solutions by designing innovative Battery Energy Storage Systems. Collaborate with engineers to deliver impactful civil designs that enhance land development proje...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$200K - $235K *

Empower organizational strategy and execution in Security & Technology, driving cross-functional initiatives and enhancing communication. Collaborate with leadership to optimize operations and inspire...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$199K - $274K *

Transform enterprise-scale engineering capabilities by leading the TORC function, fostering collaboration across security and operations, and delivering innovative solutions for risk and control manag...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$160K - $180K *

Lead the charge in strategic ERP advisory engagements, guiding clients through enterprise transformation and technology alignment to drive impactful change and enhance organizational readiness across...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$240K - $260K *

Elevate your career by leading utility-scale solar PV and BESS projects. Drive growth, foster partnerships, and enhance project delivery through strategic leadership and operational excellence across...

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $150K *

Shape the future of safety in a dynamic environment by developing and enhancing EHS programs. Collaborate across teams to foster a culture of safety and compliance, ensuring adherence to regulations w...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $145K *

Shape the future of healthcare technology by designing and implementing innovative care management tools. Collaborate with teams to create reliable software solutions while mentoring others and advanc...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $100K *

Innovate user experiences by managing and enhancing the Salesforce platform. Collaborate with stakeholders to translate business needs into effective solutions, ensuring data quality and user adoption...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Transform our web presence by owning strategy and optimization across multiple domains, enhancing user engagement, driving conversions, and managing a high-performing team to create a seamless and eff...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Staffing

$192K - $229K *

Lead the charge in delivering comprehensive data migration services for SAP-enabled transformations, ensuring effective governance, client engagement, and execution of best practices across diverse da...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$197K - $232K *

Lead growth in a dynamic sales team focused on enterprise accounts, driving execution and collaboration to enhance market reach and customer relationships. Shape strategy and sales processes while bui...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive automated security solutions by designing and implementing Super Intelligence capabilities, enhancing threat detection and response across integrated security technologies while collaborating wi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.