Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Sr Global Product Manager, Digital Solutions - Surgical & Procedural Care
$149K - $224K *
Lead the charge in shaping digital solutions for perioperative workflows, driving strategy and execution across cross-functional teams to enhance clinical outcomes and operational efficiency in surgic...
4 days ago
Clinical Applications Specialist, Invasive Cardiology
$92K - $138K *
Elevate your career by delivering expert clinical education and training. Drive customer success through hands-on support and relationship building, optimizing product adoption and enhancing patient c...
4 days ago
Biomedical Equipment Technician 2
$65K - $98K *
Reimagine service excellence by diagnosing and repairing complex biomedical equipment, ensuring safety and compliance, and fostering strong relationships with customers and teams to drive overall sati...
Reposted 4 days ago
Senior Director of Strategy - Women's Health
$176K - $264K *
Optimize product management for Women's Health in North America, driving strategy, revenue growth, and market share. Collaborate with stakeholders to tailor solutions and enhance customer insights, en...
4 days ago
HFS USCAN Operations Leader- Equipment Leasing & Loan
$126K - $189K *
Optimize operational strategies and drive excellence in leasing and loan services. Lead cross-functional teams, enhance customer satisfaction, and implement scalable systems to support strategic growt...
4 days ago
Lead Customs Specialist 1 - Customs Operations
$96K - $144K *
Lead cross-functional initiatives to enhance customs operations, ensuring compliance and optimizing performance. Drive process improvements and manage a high-performing team while leveraging data anal...
4 days ago
Clinical Application Specialist, Point-of-Care Ultrasound - Tennessee
$80K - $95K *
Empower clinical excellence by delivering expert training and support for Point of Care Ultrasound solutions, enhancing customer relationships and driving business growth across Central and Eastern Te...
4 days ago
Financial Services Ops Manager
$81K - $122K *
Transform documentation processes by ensuring compliance, accuracy, and accessibility. Collaborate with cross-functional teams to enhance operational efficiency and support seamless integration of doc...
4 days ago
Onsite Patient Monitoring Project Manager - Georgia/Alabama
$90K - $110K *
Elevate patient care by leading project management for healthcare solutions. Drive implementation, ensure customer satisfaction, and coordinate resources while managing multiple projects in a dynamic...
4 days ago
Virtual Sales Account Manager, Ultrasound
$90K - $110K *
Drive market growth by managing a robust order funnel, collaborating with sales teams and partners to exceed revenue targets while developing strategic account plans and maintaining strong customer re...
4 days ago
Producst Sales Specialist-General Imaging - St. Louis
$90K - $110K *
Champion sales growth by developing strategic relationships and driving GI Ultrasound product sales. Leverage market insights to enhance customer engagement and achieve revenue targets while maintaini...
4 days ago
$110K - $130K *
Lead the charge in driving sales strategy for the CT product line across the Ohio Valley. Cultivate relationships, maximize revenue, and collaborate with cross-functional teams to enhance market share...
4 days ago
$116K - $155K *
Join a team that's dedicated to enhancing AI governance and risk management. You'll implement frameworks, monitor compliance, and engage with key stakeholders to ensure effective policy adoption and m...
Reposted 4 days ago
Insurance Litigation Attorney (CA License Required) – Remote
$150K - $200K *
Champion the management of insurance litigation files, providing mentorship and expertise while navigating complex legal matters and advocating for clients in a dynamic remote work environment...
Reposted 4 days ago
Principal Software Engineer - Emerging Technology & AI - Remote
$177K - $236K *
Transform the future of technology as a Principal Software Engineer, leading AI experimentation and prototyping. Collaborate across teams to design scalable solutions, mentor engineers, and drive inno...
4 days ago
$92K - $135K *
Join our Finance, Risk & Compliance team as a Senior Financial Analyst, driving financial planning, budgeting, and reporting processes. Collaborate with departments to enhance insights and efficiency...
4 days ago
Senior Application Sales Engineer - Power Transformers
$110K - $130K *
Drive innovative solutions in technical sales for power transformers, collaborating with key stakeholders to secure new business and enhance customer relationships while leveraging engineering experti...
4 days ago
$110K - $130K *
Lead the charge in transforming client challenges into innovative Salesforce solutions. Collaborate with stakeholders to design, demo, and scope projects, ensuring seamless transitions to delivery whi...
4 days ago
Senior Director, Web Strategy and Operations
$160K - $200K *
Shape the future of our web strategy by leading a cross-functional team to optimize user experience, drive demand generation, and enhance web performance. Your expertise will transform our website int...
4 days ago
Account Manager - Encaps and Inclusions
$80K - $95K *
Grow your career by driving sales and expanding market presence in the Encaps & Inclusions sector. Collaborate with cross-functional teams to deliver innovative solutions while managing key accounts a...
4 days ago
Strategic Account Manager-QSR & Casual Dining
$80K - $95K *
Shape the future of customer engagement by managing key accounts, driving revenue growth, and enhancing client satisfaction in the QSR and Casual Dining sectors. Collaborate across departments to impl...
4 days ago
$85K *
Champion quality assurance by developing and executing test strategies to ensure technology solutions meet business and user requirements. Collaborate with cross-functional teams to enhance applicatio...
4 days ago
$120K - $140K *
Empower organizational success by leading total rewards programs, ensuring competitive compensation and benefits. Collaborate with HR and finance to drive compliance and continuous improvement, while...
4 days ago
Director, Engineering, Data, and AI
$150K - $180K *
Drive operational excellence by leading engineering, data, and AI teams. Collaborate with stakeholders to translate strategic goals into actionable plans, ensuring high-quality project delivery and te...
4 days ago
CV Ultrasound Clinical Solution Consultant Manager - Midwest Zone
$207K - $225K *
Drive business growth and customer satisfaction by leading a high-performing Cardiovascular Clinical Solutions Consultant team, collaborating across sales and clinical operations to enhance customer e...
4 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.