Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$95K - $115K *

Contribute to operational excellence by assessing and optimizing manufacturing processes, advising on improvements, and implementing tailored ERP solutions for clients in batch and process industries...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by designing and implementing enterprise identity solutions, ensuring secure access across cloud and hybrid environments while collaborating with cross-functional teams to enhance IAM...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Unlock potential by leading ESG and sustainability strategies for business aviation. Collaborate with industry partners and Fortune 500 clients to navigate regulations, develop innovative solutions, a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$125K - $150K *

Champion growth by developing new enterprise accounts in Healthcare and Financial Services. Leverage strategic relationships and innovative solutions to drive business value and expand market presence...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$260K - $270K *

Unlock your potential as a Psychiatrist, providing advanced outpatient care via virtual platforms. Collaborate with multidisciplinary teams to deliver comprehensive treatment for diverse psychiatric c...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$88K - $111K *

Innovate with us to drive product-led sales in the higher education sector, empowering universities by promoting research analytics solutions. Collaborate with teams to achieve substantial growth and...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engage in a dynamic role leading security operations and AI integration. Oversee real-time threat monitoring and incident response while developing automated workflows in a cutting-edge, multi-tenant...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $155K *

Join a team that's dedicated to providing virtual behavioral health services to military personnel. Utilize your expertise in clinical psychology to deliver evidence-based treatments and support patie...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $120K *

Join a dynamic team to drive sales of innovative laboratory equipment in the Northeast. Engage with clients, deliver product demos, and exceed sales targets while fostering strong relationships and pr...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $200K *

Lead the charge in managing complex litigation and advising on legal risks, ensuring compliance while collaborating with internal teams and outside counsel to drive effective case strategies and resol...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Unlock potential by leveraging your expertise in structured settlements to build strong relationships with personal injury attorneys, driving business growth and ensuring clients receive top-notch set...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Engage with personal injury attorneys to build trust and drive settlement planning referrals. Leverage your expertise in financial planning and relationship management to generate new business opportu...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Partner with us to drive commercial CRM solutions for pharma, leading requirements gathering and process design. Collaborate with stakeholders to ensure effective system implementation and user adopti...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive operational excellence by leading cross-functional initiatives, simplifying processes, and embedding continuous improvement practices to enhance safety, quality, and productivity while aligning...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$104K - $155K *

Lead the charge in customer-focused project management, ensuring effective delivery of technical solutions while coordinating with diverse stakeholders and fostering strong relationships for successfu...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Elevate your career by leading the charge in relay testing and commissioning for power systems. This role involves mentoring, technical excellence, and ensuring the reliability of protection and contr...

South Dakota, USRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$180K - $230K *

Lead the charge in designing and delivering innovative Azure data solutions, ensuring technical excellence and client satisfaction while guiding teams through complex implementations and strategic eng...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $141K *

Empower financial strategies by analyzing interest rate and liquidity risks. Collaborate with stakeholders to enhance capital planning and reporting processes while ensuring compliance with regulation...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $150K *

Lead the charge in executive support and strategic sales initiatives, managing schedules, communications, and events for the EVP of Global Client Services. Drive efficiency and stakeholder engagement...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $140K *

Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$93K - $150K *

Optimize infrastructure and CI/CD pipelines to empower engineering teams in delivering AI-powered products efficiently. Collaborate closely with product and data engineers, leading projects from incep...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Champion financial excellence by leading a dynamic team, ensuring compliance, and delivering strategic insights to clients. Drive operational efficiency and foster a collaborative environment while ma...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$250K *

Grow your career with a strategic role focused on developing long-term partnerships with key industrial customers, enhancing relationships across multiple service lines, and driving revenue growth thr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock your potential as a Program Manager, leading federal service contracts and driving operational excellence. Collaborate with teams to ensure quality delivery, financial performance, and customer...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$205K - $231K *

Drive your career with impactful security initiatives that enhance product safety and foster responsible AI development. Collaborate across teams to elevate security practices and implement robust gua...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.