Welcome to the South Dakota Job Category

South Dakota, known for its diverse economy and strong job market, hosts a variety of high-paying job opportunities in different sectors. Whether you are looking for roles in healthcare, technology, finance, or other professional industries, Ladders has got you covered.

Why South Dakota?

With a low unemployment rate and fast-growing industries, South Dakota is a promising place to level up your career. Explore the vast opportunities spread across the Mount Rushmore State with Ladders.

Find Your Dream Job in South Dakota

Navigate the professional job market in South Dakota with ease using our curated, vetted job postings. Join Ladders to discover the lucrative job opportunities in South Dakota that await you.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,584

Sort By: Relevance

$150K - $200K *

Empower patient outcomes by administering anesthesia and collaborating with medical teams. Create effective pre-anesthetic plans, monitor patients, and enhance care across surgical and non-surgical pr...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $130K *

Accelerate your career by generating qualified leads for enterprise accounts. Engage key decision-makers and drive revenue growth in a dynamic environment focused on building trust in AI solutions. Be...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $140K *

Contribute to multiple smaller-scale IT projects, managing implementation lifecycles. Engage with clients and coordinate with tech teams to ensure timely delivery while maintaining clear project docum...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$125K - $180K *

Join a global team to architect and optimize high-scale data pipelines, integrating diverse data sources for analytics and AI insights. Play a key role in ensuring reliability and scalability across a...

US-AnywhereRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$111K - $149K *

Innovate your career as you craft compelling copy for diverse media, shaping creative strategies for financial clients. Collaborate cross-functionally to ensure alignment with brand objectives while m...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Media

$175K - $200K *

Help us empower educational leaders by driving AI-first product strategies that enhance outcomes for students and educators. In this leadership role, you'll foster a culture of inclusion and accountab...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$117K - $152K *

Empower your career by leading a dynamic software development team. Oversee project delivery, mentor talent, and ensure high standards in software quality and agile practices while driving innovation...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$90K - $120K *

Join a dedicated team of clinical pharmacists to optimize patient medication management and outcomes through collaboration, quality improvement, and support across care settings, ensuring compliance w...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Champion strategic HR initiatives across USA and EU, providing expert partnership and support for a high-growth startup while ensuring compliance in diverse employment environments...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Business Services

$80K - $128K *

Lead the charge in managing advanced Energy Management Systems for military housing, blending technical expertise with operational oversight to optimize building performance and enhance energy efficie...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $130K *

Take ownership of statistical support and leadership for oncology clinical trials. Collaborate with cross-functional teams to enhance study design, reporting, and analysis while ensuring high-quality...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Join us to optimize and support critical pharmaceutical applications such as Veeva Vault and CRM. Collaborate with cross-functional teams to improve operations, enhance system functionality, and ensur...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Drive impactful content creation to establish thought leadership and engage audiences. Spearhead brand and sales enablement content, leveraging proprietary AI insights and industry expertise to define...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$90K - $120K *

Partner with us to enhance operational stability and support cloud-based web applications. You'll lead incident resolution, collaborate with stakeholders, and drive compliance initiatives ensuring a s...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$125K - $160K *

Redefine clinical budget management by leading negotiations and coordinating between clinical research and legal teams to ensure timely, compliant research operations while driving continuous improvem...

US-AnywhereIn-Person

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in revolutionizing healthcare delivery by owning the entire product ecosystem. Drive innovation across patient applications, clinician workflows, and AI integrations to shape impactful...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$116K - $145K *

Oversee translational research to enhance oncology programs, leading studies to analyze mechanisms of action, resistance pathways, and biomarkers. Collaborate with CROs and ensure compliance in delive...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$167K - $226K *

Join a team that's redefining transportation management by leveraging SAP S/4 TM standards to optimize technology investments, drive innovation, and deliver outstanding value for business, partners, a...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Transportation

$90K - $120K *

Deliver critical systems engineering support for platform integration, planning, and analysis. Engage in diverse projects, contribute to advanced technologies, and grow your career in a dynamic remote...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $110K *

Lead the charge in quality assurance by designing, executing, and maintaining automated tests for enterprise applications, collaborating with teams to streamline operations and enhance product reliabi...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$150K - $200K *

Lead development initiatives from concept to completion, driving strategic direction in commercial real estate projects. Oversee budget, team leadership, and site evaluations to ensure timely and cost...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$84K - $105K *

Champion the growth of key academic accounts by managing sales activities, coordinating resources, and fostering collaboration across teams to achieve long-term revenue success in the education techno...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a dynamic team as you drive successful partnership implementations, ensuring timely onboarding and program success while collaborating across various teams to meet growth objectives and enhance c...

US-AnywhereIn-Person

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$180K *

Empower a high-performing team as a Systems Engineering Manager, overseeing system platforms and operations. Lead hiring, training, and performance evaluation while driving improvements in processes a...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$83K - $111K *

Shape the future of financial planning by assisting clients in optimizing their investments and securing their financial goals while ensuring compliance with all regulations and enhancing client relat...

US-AnywhereIn-Person

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kind of high-paying jobs are available in South Dakota?question toggle

    South Dakota has a robust job market with high-paying positions in healthcare, IT, finance, manufacturing, and more.

  • Why should I consider working in South Dakota?question toggle

    South Dakota is known for its diverse economy, low unemployment rate, and range of industries. It's a great location for professionals looking to advance their careers.

  • Can I find jobs that pay over $100000 in South Dakota?question toggle

    Yes, at Ladders you can find many jobs in South Dakota that pay over $100000.

  • How can Ladders help me in finding high-paying jobs in South Dakota?question toggle

    Ladders provide vetted, high-paying job postings and tools to help you navigate the professional job market in South Dakota.