Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Technical Customer Enablement Manager
$73K - $100K *
Accelerate progress at the intersection of technology and customer experience, guiding clients through successful implementation and adoption of technical solutions while equipping internal teams for...
Reposted 3 weeks ago
Senior Fullstack Engineer, Core Products
$124K - $134K *
Innovate and optimize our core fintech systems, leveraging AI-driven technologies while owning end-to-end product development. Collaborate with cross-functional teams to ensure impactful user experien...
Reposted 3 weeks ago
Detection & CorpSec Engineer (Remote)
$172K - $249K *
Join our dynamic Security team to build and maintain detection systems while protecting corporate and production environments. Leverage your expertise in security engineering to enhance our defenses a...
Reposted 3 weeks ago
Territory Account Manager, Enterprise Sales - US
$110K - $130K *
Transform enterprise growth by building and managing strategic channel partnerships. Drive engagement with value-added resellers and enterprise customers, ensuring sustained revenue through expert net...
Reposted 3 weeks ago
$95K - $124K *
Transform corporate legal operations by managing due diligence, governance, and vendor relationships. Collaborate across teams to ensure compliance and streamline processes, while supporting attorneys...
3 weeks ago
Electrical and Controls Supervisor
$80K - $95K *
Lead the charge in supervising electrical maintenance activities, ensuring safety and compliance while optimizing team performance and equipment reliability. Drive continuous improvement in electrical...
3 weeks ago
$250K - $275K *
Drive the transformation of banking by guiding product strategies for an innovative Banking as a Service platform, ensuring alignment across teams to deliver impactful financial solutions...
Reposted 3 weeks ago
Senior Revenue Enablement Manager
$110K - $130K *
Drive enablement and coaching for the Revenue organization, crafting impactful programs and playbooks for BDRs, AEs, and CSMs. Partner cross-functionally to enhance sales effectiveness, while owning s...
Reposted 3 weeks ago
$220K - $248K *
Lead the charge in developing innovative financial products through our Banking as a Service platform, utilizing first principles thinking to create a user-focused experience while collaborating acros...
Reposted 3 weeks ago
$110K - $130K *
Pioneer product partnerships by driving strategy and execution for growth. Collaborate cross-functionally to evaluate opportunities, negotiate terms, and ensure long-term success while representing th...
Reposted 3 weeks ago
Principal Product Manager - Content
$135K - $160K *
Transform the content landscape by spearheading product strategy and enhancing customer experiences. Leverage AI and market insights to innovate a comprehensive product portfolio while ensuring editor...
Reposted 3 weeks ago
$170K - $190K *
Unlock your future as a strategic leader driving product marketing initiatives. Oversee messaging, competitive intelligence, and go-to-market strategies while developing a high-performing team to prop...
Reposted 3 weeks ago
Managing Director - Digital Infrastructure, Investment Banking
$210K - $250K *
Lead growth initiatives in digital infrastructure investment banking, driving deal origination, client relationships, and team mentorship while ensuring exceptional service delivery and execution exce...
Reposted 3 weeks ago
Senior Manager, Customer Support & Success
$110K - $130K *
Empower customer success by leading a high-performing team to enhance support experiences, drive retention, and build proactive strategies. Shape the future of customer engagement through data-driven...
3 weeks ago
Senior Revenue Operations Leader
$175K - $190K *
Transform revenue operations by leading AI-driven initiatives, optimizing tech stacks, and enhancing cross-functional collaboration. Drive measurable outcomes while building a high-performing team tha...
3 weeks ago
$130K - $155K *
Transform the Postgres product by owning full-stack projects and collaborating with cross-functional teams, ensuring user experience is prioritized as the service scales and evolves with customer need...
Reposted 3 weeks ago
Staff Product Manager - Agent & Systems Observability
$135K - $160K *
Transform observability in AI with strategic vision, driving technical progress across systems and agent telemetry, while enhancing developer experiences and guiding product direction at the intersect...
Reposted 3 weeks ago
Senior Colleague Modernization Engineer
$120K - $145K *
Innovate your career by leading SaaS modernization projects, enhancing delivery efficiency through AI and automation. Drive customer success by transforming legacy systems into scalable, sustainable s...
3 weeks ago
$170K - $230K *
Accelerate your career by driving growth through strategic partnerships. Own the complete lifecycle from sourcing to managing affiliate partnerships that enhance our customer acquisition and revenue s...
Reposted 3 weeks ago
Business Development Senior Director
$160K - $200K *
Partner with us to lead transformative business development initiatives in life sciences. Drive revenue through strategic engagement with pharma/biotech partners, managing the full sales cycle and ens...
Reposted 3 weeks ago
Channel Account Manager, Central
$110K - $130K *
Grow and innovate the partner ecosystem in the Central US by building and executing strategic channel plans, fostering relationships, and driving revenue through effective partnerships in the dynamic...
Reposted 3 weeks ago
Strategic Account Executive (Chicago & Texas)
$125K - $150K *
Deliver impactful voice AI solutions by driving strategic account growth and managing complex sales cycles. Collaborate across teams to exceed sales targets while fostering relationships with key stak...
Reposted 3 weeks ago
Senior Technical Project Manager
$110K - $130K *
Transform the onboarding experience for enterprise customers by leading seamless implementations, balancing technical demands with stakeholder communication, and driving effective project management t...
Reposted 3 weeks ago
$175K - $200K *
Engage with engineering teams to embed security in workflows, conduct architecture reviews, and enhance product security. Support the development of security programs while mentoring engineers and ove...
Reposted 3 weeks ago
Senior/Staff AI Scientist, Antibody Design
$150K - $180K *
Transform innovative protein design through advanced AI techniques, enhancing antibody drug discovery. Collaborate across disciplines to maximize efficiency and impact, while leading research that set...
Reposted 3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.