Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Project Manager, Delivery Lead
$95K - $115K *
Elevate project delivery by leading cross-functional teams in Interactive Response Technology, ensuring client satisfaction and timely execution while managing risks and fostering continuous improveme...
2 weeks ago
$108K - $156K *
Empower your career by leading revenue analytics, overseeing financial analysis, and enhancing payer contract strategies. Collaborate with cross-functional teams to optimize reimbursement and drive or...
2 weeks ago
Sales Representative New Business Midwest US
$80K - $100K *
Elevate your career by driving sales growth through strategic prospecting and collaboration. Leverage market knowledge and CRM tools to enhance customer relationships while managing a dynamic territor...
2 weeks ago
GovCon Technology Senior Manager (with Deltek Costpoint experience)
$133K - $262K *
Engage with clients and lead projects through all phases to achieve project goals while enhancing methodologies and tools tailored for the government contracting industry. Drive business development a...
Reposted 2 weeks ago
Phoenix, AZ based Territory Sales Manager - Remote, USA
$120K - $260K *
Lead the charge in driving CVAC adoption among physicians, exceeding sales quotas while building strong relationships. Utilize your expertise to train and develop accounts, ensuring our technology bec...
2 weeks ago
$160K - $200K *
Champion the future of client solutions by leading strategy, product innovation, and executive relationships. Drive growth and operational excellence across a diverse partner portfolio while building...
2 weeks ago
Lead Infrastructure Engineer - Hybrid Cloud & Automation Solutions
$130K - $155K *
Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...
2 weeks ago
Associate State Product Manager - Personal Lines
$88K - $132K *
Transform state-specific strategies by analyzing data, supporting financial planning, and collaborating with cross-functional teams to drive performance in the Personal Lines portfolio, ensuring compe...
2 weeks ago
Vice President, Strategic Account Management
$140K - $160K *
Transform your career by leading strategic account management for top Healthcare clients. Drive client satisfaction, revenue growth, and operational excellence while collaborating with cross-functiona...
2 weeks ago
$60K - $120K *
Unlock potential by deploying and supporting advanced robotic systems in diverse environments. Collaborate with teams, troubleshoot issues, and enhance client experiences through effective communicati...
2 weeks ago
Senior Merchant Success Manager
$81K - $135K *
Support enterprise merchants by enhancing their experience, driving growth, and fostering strategic relationships. Collaborate with teams to optimize performance and deliver exceptional value while ma...
2 weeks ago
Enterprise Architect - Clearance Required
$120K - $180K *
Unlock the potential of Army logistics by driving enterprise architecture, cybersecurity, and systems integration initiatives. Collaborate with stakeholders to enhance business processes and deliver i...
2 weeks ago
$24K - $500K+*
Grow your career by expanding our customer base and building strong relationships with contractors. Drive sales strategy execution, manage territory, and enhance customer satisfaction in a dynamic con...
2 weeks ago
$92K - $138K *
Join our team to lead the Virtual Utilization Management Program, ensuring clinical excellence and operational efficiency. Collaborate with diverse healthcare professionals to enhance patient care and...
2 weeks ago
Sr Director Analyst, Direct Procurement
$172K - $202K *
Unlock innovative insights and strategies in procurement and supply chain leadership. Collaborate with executives to drive actionable solutions, analyze market trends, and enhance client engagement th...
2 weeks ago
$67K - $105K *
Join a dynamic team to manage client accounts, delivering trust and estate planning services while ensuring compliance and fostering strong client relationships. Drive financial strategies and collabo...
2 weeks ago
$215K - $235K *
Advance drug substance development and drive clinical readiness projects by leading process chemistry initiatives, collaborating with cross-functional teams, and ensuring regulatory compliance for suc...
Reposted 2 weeks ago
Senior Technical Program Manager, Consumer
$193K - $228K *
Join a dynamic team to lead complex, cross-functional programs, ensuring timely delivery of high-quality features while driving alignment across Product, Engineering, and Design teams in a fast-paced...
2 weeks ago
Lead Enterprise Revenue Architect (Customer Success)
$148K - $225K *
Join a team that's transforming revenue operations through AI-driven insights. You'll collaborate with senior leaders, architect workflows, and drive adoption to ensure measurable business outcomes ac...
Reposted 2 weeks ago
Director, Global Partner Marketing
$150K - $180K *
Champion a global partner marketing strategy that drives measurable revenue through collaboration with partners, sales, and marketing teams. Lead a distributed team to create impactful go-to-market pr...
2 weeks ago
Regional Customer Success Manager (Automotive)- CHICAGO
$80K - $95K *
Empower customer success by driving engagement and satisfaction for automotive clients. Develop strategies to enhance product adoption, mitigate churn, and foster strong relationships, ensuring custom...
2 weeks ago
Territory Manager - Manhattan, NY
$100K *
Elevate sales performance by driving demand for portable ultrasound systems through strategic networking, cold calling, and consultative selling in a dynamic healthcare environment, while managing key...
2 weeks ago
Senior Product Manager | Applied AI
$135K - $160K *
Champion the vision and strategy for AI-powered products, driving their roadmap and delivery while mentoring peers. Leverage AI tools to enhance decision-making and product lifecycle management, ensur...
2 weeks ago
Technical Game Designer (Level)
$80K - $95K *
Join a team that's transforming gameplay experiences by designing immersive worlds and interactive features in Unreal Engine. Collaborate across disciplines to create engaging multiplayer environments...
2 weeks ago
Software Engineer || (Authentication)
$107K - $132K *
Join a team that's shaping the future of cloud services and authentication systems. As a key contributor, you'll design, build, and maintain scalable, secure solutions while collaborating with cross-f...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.