Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Sr. Database Engineer, Postgre SQL/AWS Aurora
$140K - $150K *
Unlock potential by enhancing our PostgreSQL database for a high-volume legal services platform. Collaborate with cross-functional teams to optimize performance, ensure data integrity, and automate ma...
2 weeks ago
Senior Operations Engineer, CX
$120K - $150K *
Drive operational excellence by designing and enhancing technology systems that elevate customer experience. Lead cross-functional initiatives, leveraging AI and automation to create scalable solution...
2 weeks ago
$176K - $293K *
Develop and implement strategic account plans to drive sales growth and build relationships with key decision-makers in healthcare. Collaborate with cross-functional teams to achieve business goals an...
2 weeks ago
$61K - $102K *
Join a dynamic team to deliver advanced training on CensiTrac software, enhancing customer engagement and success. Utilize your expertise in sterile processing to provide solutions and support, ensuri...
2 weeks ago
Senior Technical Consultant - Data & Analytics
$160K - $200K *
Lead the charge in designing and implementing scalable data solutions, orchestrating pipelines, and supporting advanced analytics in cloud environments. Collaborate with teams to deliver robust data a...
2 weeks ago
$160K - $190K *
Elevate our talent acquisition by architecting AI-driven recruiting workflows. Lead the design, deployment, and optimization of innovative solutions that enhance hiring efficiency and candidate experi...
2 weeks ago
Strategic Partner Executive, CDW
$277K - $320K *
Empower strategic partnerships by leading the development and execution of a multi-year business strategy with key channel partners, driving revenue growth and enhancing collaborative relationships ac...
2 weeks ago
Principal SAP HCM & SF Payroll Consultant
$114K - $167K *
Unlock your potential as you analyze and optimize complex ERP systems, driving innovative solutions and integrations while ensuring compliance and performance excellence in a dynamic, remote environme...
2 weeks ago
Host-Nation Engagement & Integration Director
$150K - $180K *
Transform mission execution across the Indo-Pacific by leading host-nation engagement and integration efforts. Collaborate with diverse stakeholders to enhance planning, coordination, and problem-solv...
2 weeks ago
Director, Advanced Analytics and Data Science - Innovation
$174K - $234K *
Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...
Reposted 2 weeks ago
Account Executive - Federal Government (Remote, United States)
$110K - $130K *
Unlock new business opportunities within U.S. Federal Government agencies by driving strategic sales initiatives, building executive relationships, and navigating complex procurement processes to enha...
2 weeks ago
$220K - $250K *
Unlock potential by driving strategic partner relationships and collaborating across teams to enhance solution development, enabling partners to achieve measurable outcomes while promoting business gr...
Reposted 2 weeks ago
$115K - $138K *
Join us to lead channel marketing initiatives, driving program management and analytics. Collaborate with cross-functional teams to enhance dealer support and optimize marketing strategies, ensuring e...
2 weeks ago
Senior Strategic Events Manager
$118K - $170K *
Join a team that's redefining event excellence by leading strategic, high-impact programs. You'll manage diverse events from inception to execution, ensuring every detail aligns with our vision and dr...
2 weeks ago
$150K - $180K *
Lead the charge in building and scaling strategic partnerships to drive revenue growth. Oversee the entire partner lifecycle, from selection to enablement, ensuring successful collaboration and measur...
2 weeks ago
Sr Director Sales Enablement & Training
$209K - $349K *
Join a team that's driving sales enablement and training initiatives to enhance commercial performance. Lead strategic programs that empower teams, foster continuous learning, and ensure effective cus...
2 weeks ago
Sr. Software Engineer - Front-End
$125K - $200K *
Join a team that's dedicated to enhancing user engagement through innovative front-end solutions. You'll leverage modern web technologies to build secure, high-performance financial applications that...
2 weeks ago
Senior Manager, Digital Securities & Market Structure Policy
$252K - $297K *
Lead the charge in shaping digital asset market structure policy by engaging with the SEC, developing comment strategies, and translating regulatory changes into actionable guidance for stakeholders a...
2 weeks ago
$110K - $130K *
Empower your career by driving strategic alliances and co-sell initiatives. Collaborate with Microsoft teams to identify opportunities, enhance relationships, and deliver impactful solutions that fost...
2 weeks ago
Account Manager - Finance and Accounting
$110K - $130K *
Grow your career by building and cultivating strong client relationships while driving innovative solutions in the Finance and Accounting domain, collaborating with top talent to achieve lasting succe...
Reposted 2 weeks ago
Service Line Leader - Environmental Restoration & Health
$180K - $200K *
Advance environmental restoration initiatives for federal clients by leading multidisciplinary teams, developing strategic growth plans, and ensuring compliance with regulatory standards while driving...
2 weeks ago
Director of Strategic Partnerships
$100K - $150K *
Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...
2 weeks ago
Senior Manager, Pain Portfolio
$129K - $185K *
Innovate global medical strategies for the Companion Animal Pain portfolio, driving growth and customer value through scientific engagement, KOL collaboration, and effective market implementation acro...
2 weeks ago
Account Executive - Logging Recorder
$85K - $115K *
Join a dynamic team to drive sales of mission-critical technology for public safety. Engage with emergency response agencies, navigate complex procurement cycles, and deliver innovative solutions that...
2 weeks ago
$140K - $150K *
Join a team that's driving strategic project execution and mentoring talent. Leverage advanced data analytics to build impactful dashboards and navigate stakeholder relationships, ensuring alignment w...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.