Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$160K - $340K *
Grow your career with a strategic role focused on expanding key accounts and winning new enterprise logos. Engage with top-tier clients, drive complex sales cycles, and collaborate across teams to del...
2 weeks ago
$80K - $95K *
Elevate your career by partnering with us to optimize enterprise network performance. You'll troubleshoot complex issues, collaborate with cross-functional teams, and drive improvements to ensure secu...
2 weeks ago
$80K - $95K *
Transform your career by enhancing data security and integrity. Collaborate with cross-functional teams to implement robust security measures, conduct audits, and mitigate risks while staying ahead of...
2 weeks ago
$115K - $156K *
Pioneer innovative maintenance processes and CMMS capabilities, driving global engineering operations. Collaborate with stakeholders to enhance asset management, reliability, and sustainability while...
2 weeks ago
$90K - $110K *
Elevate your technical expertise by supporting L1 teams, running investigations, and shipping bug fixes. Collaborate across departments to enhance product quality and customer satisfaction in a dynami...
2 weeks ago
Director, Managed Markets - Regional - West
$235K - $270K *
Elevate your career by leading access strategy across the Mountain and Pacific territories. Drive relationships with regional payers and ensure launch readiness for rare disease products while collabo...
2 weeks ago
Senior Substation Engineer 2 - Grid
$100K - $152K *
Accelerate your career by leading high voltage substation projects, collaborating with engineers to solve complex electrical issues, and enhancing your skills through peer learning and client interact...
Reposted 2 weeks ago
Professional Services Consultant
$124K - $138K *
The Professional Services Consultant at Mindtickle is responsible for delivering solutions to customer enablement challenges using the Mindtickle SaaS platform. This role involves project management...
Reposted 2 weeks ago
VP Finance & Global Controller
$175K - $210K *
Elevate your career by leading global financial operations, ensuring accurate reporting and compliance across multiple entities. Drive innovation in financial systems and processes while mentoring a h...
2 weeks ago
Consulting National Partner Technical Manager
$156K - $234K *
Transform partner relationships by driving technical enablement and sales success. Collaborate with cross-functional teams to align strategies, mentor partners, and enhance market presence through inn...
2 weeks ago
$135K - $150K *
Accelerate progress at a leading firm by driving sales in the Tourism sector. Leverage your expertise to build client relationships, close deals, and collaborate cross-functionally, all while managing...
2 weeks ago
Group Account Supervisor - Healthcare and Pharmaceutical Advertising
$100K - $139K *
Lead a dynamic account team to drive strategic growth and client relationships. Oversee financial management and tactical execution while fostering team development and ensuring high-level client sati...
2 weeks ago
Partner Success Manager, Broker
$95K - $115K *
Empower partner success by managing relationships, enhancing product adoption, and driving engagement. Collaborate with cross-functional teams to deliver exceptional service and support, ensuring part...
2 weeks ago
Senior Enterprise Relationship Manager
$100K - $120K *
Manage a portfolio of strategic enterprise clients, fostering executive relationships and driving retention and adoption. Utilize data and AI tools to enhance client value, mentor team members, and sh...
2 weeks ago
Associate Director, Business Improvement
$130K - $160K *
Reimagine business improvement strategies as a senior contributor, leading high-impact initiatives across functions. Drive alignment, governance, and measurable outcomes while influencing stakeholders...
2 weeks ago
Senior Software Development Engineer - Verity Solutions - Remote
$130K - $217K *
Lead the charge in designing innovative, scalable software solutions that transform complex processes into actionable insights, partnering with diverse teams to deliver high-performance applications f...
Reposted 2 weeks ago
Sr. Engineer, Skylar Automation
$120K - $145K *
Transform mission-critical applications by designing and developing scalable solutions. Collaborate with cross-functional teams to ensure reliability and performance while leveraging cloud infrastruct...
2 weeks ago
Senior Technical Program Manager
$200K - $220K *
Empower the future of financial operations by mastering money movement, ensuring seamless transactions and transparency. Collaborate with cross-functional teams to drive product success and enhance cl...
2 weeks ago
People Systems and Solutions Manager
$188K - $235K *
Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...
2 weeks ago
Director, Neurology - Thought Leader Liaison (Central)
$245K - $265K *
Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...
2 weeks ago
$180K - $220K *
Engage with key stakeholders to drive sales growth in the Labor market. Develop strategies, build relationships, and present solutions to exceed targets while navigating complex opportunities and fost...
2 weeks ago
Vice President Advisory Relations
$180K - $220K *
Shape the future of government solutions by driving strategic partnerships and market growth. In this executive role, you'll cultivate relationships with key advisory firms, ensuring our data and tech...
2 weeks ago
$110K - $130K *
Innovate revenue operations by owning the order-to-cash process, enhancing billing systems, and implementing automation. Collaborate with cross-functional teams to streamline revenue recognition and e...
2 weeks ago
Growth Sales Executive - Enterprise and Partnerships
$100K - $120K *
Join a team that's transforming patient care access by owning the mid-market and enterprise pipeline, building partnerships, and navigating complex deals to drive impactful growth in a collaborative s...
2 weeks ago
Senior Platform Engineer, MarTech
$145K - $165K *
Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.