Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$174K - $291K *
Lead strategic initiatives to drive revenue growth across federal civilian agencies. Manage complex sales cycles, build customer relationships, and coordinate cross-functional teams to align solutions...
2 weeks ago
Sr. Talent Acquisition Partner
$100K - $120K *
Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...
Reposted 2 weeks ago
$130K - $145K *
Lead the charge in driving client success and commercial growth by managing strategic relationships, identifying upsell opportunities, and ensuring client satisfaction across a diverse portfolio in th...
2 weeks ago
$90K - $100K *
Join a dynamic team as you craft precise architectural specifications, collaborating with architects to ensure high-quality project documentation and stay ahead of industry trends. Elevate your career...
2 weeks ago
$145K - $185K *
Champion the growth of Army Aviation business by identifying, shaping, and executing new opportunities. Build trusted relationships, lead contract execution, and drive portfolio success while managing...
2 weeks ago
Mechanical Design Manager - Data Center Construction
$170K - $210K *
Lead mechanical design initiatives for construction projects, focusing on data centers. Collaborate with clients and teams to ensure high-quality delivery, manage project phases, and innovate solution...
2 weeks ago
Demand Generation Associate Manager
$90K - $110K *
Transform your career by owning the technical execution of lifecycle and demand generation campaigns, leveraging HubSpot and Salesforce to drive data-backed improvements and seamless sales follow-up...
2 weeks ago
Account Director, Medical Imaging and SS
$110K - $130K *
Advance your career by driving business development in clinical research and medical imaging. Build strategic client relationships, identify new opportunities, and contribute to innovative healthcare...
Reposted 2 weeks ago
Policy Administration & Contact Center Manager
$85K - $130K *
Drive team performance and enhance customer experience by overseeing policy administration and contact center operations. Collaborate on goals, manage staffing, and ensure compliance with regulations...
2 weeks ago
Channel Manager, North America
$100K - $120K *
Lead the charge in developing and executing channel strategies to drive growth, onboard high-performing partners, and enhance relationships with distributors in the life sciences sector...
2 weeks ago
$137K - $245K *
Lead the charge in driving strategic initiatives and product innovation within the Telematics Business Unit, enhancing core offerings and exploring new market opportunities through hands-on collaborat...
2 weeks ago
Staff/Director, Product Marketing Manager - IE-IoT (Remote Work Eligible)
$182K - $273K *
Inspire innovation as a Staff Product Marketing Manager bridging technical design and customer needs. Drive platform adoption through impactful messaging and competitive insights, enhancing market str...
Reposted 2 weeks ago
Regional Sales Director, Enterprise - Southeast
$148K - $248K *
Shape the future of software sales by leading a dynamic team in the Southeastern US. Drive revenue growth, enhance customer relationships, and foster a high-performing culture while leveraging GitLab...
2 weeks ago
$72K - $99K *
Join a team that's dedicated to enhancing employee experience and office operations. You'll manage daily office functions, foster a vibrant culture, and support executive initiatives, ensuring a welco...
2 weeks ago
Change Order Management Analyst - Remote, US
$88K - $154K *
Champion your career by managing change orders for large projects, evaluating contractual impacts, and ensuring effective communication with stakeholders. Collaborate with diverse teams to drive succe...
2 weeks ago
$80K - $95K *
Champion the development and execution of mission command training, mentoring unit leaders to enhance operational proficiency across various training domains. Collaborate with senior staff to ensure e...
2 weeks ago
$80K - $95K *
Unlock potential by managing month-end and year-end closes, ensuring accurate financial reporting across multiple entities. Collaborate with cross-functional teams to streamline processes and enhance...
2 weeks ago
Expert Detection and Response Engineer
$124K - $229K *
Join us to protect our players and platforms from advanced cyber threats. As a key member of our security team, you'll actively identify, investigate, and respond to security incidents, ensuring robus...
2 weeks ago
$150K - $180K *
Lead the growth and strategy of Home Services, overseeing HVAC, generators, and roofing. Drive sales, manage P&L, and build partnerships to enhance customer experience and operational efficiency in a...
2 weeks ago
Certified Public Accountant (CPA) - Medicaid/Medicare
$100K - $120K *
Elevate your career by preparing and analyzing complex Medicaid cost reports, ensuring compliance with regulations, and leading a team of accountants in a remote setting. Drive process improvements an...
2 weeks ago
Director, Digital & Performance Marketing
$162K - $244K *
Elevate your career by leading an AI-driven digital marketing strategy that transforms pipeline generation and revenue growth. Drive innovation, optimize performance, and mentor a high-performing team...
2 weeks ago
$100K - $122K *
Unlock your potential as you lead financial planning, analytics, and strategic initiatives. Collaborate closely with executives to drive performance improvements and optimize resource allocation, fost...
Reposted 2 weeks ago
Vice President Sales, TeleNeph LLC
$100K *
Elevate sales strategies by owning the full sales cycle, building C-Suite relationships, and delivering impactful solutions to healthcare organizations across the Western US...
2 weeks ago
$125K - $175K *
Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...
2 weeks ago
Product Operations Manager, Launch Readiness & Tooling
$136K - $160K *
Advance the software delivery process by managing launches and releases, ensuring accuracy and efficiency through automation and collaboration with cross-functional teams. Design workflows and tools t...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.