Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$80K - $130K *

Join a team that's driving product strategy through data analysis and insights. Collaborate with cross-functional teams to enhance product performance, uncover growth opportunities, and influence stra...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Accelerate progress at our Operations by leading efficiency initiatives that drive cost savings, enhance service, and improve overall operational excellence. Partner cross-functionally to deliver impa...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$140K - $160K *

Drive new business growth by leveraging your expertise in partnership sales, integrated marketing, and sponsorships. Collaborate with brands and agencies to create compelling solutions that meet their...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the development of scalable product operations, enhancing processes and analytics to empower cross-functional teams. Collaborate closely with stakeholders to drive product initiatives and imp...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$123K - $159K *

Build core AI platform capabilities that empower teams to develop, run, and scale GenAI applications, collaborating across the tech stack to deliver impactful solutions for millions of users in a fast...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join a dynamic team to oversee and optimize the steel supply chain for modular construction, ensuring cost-effective sourcing and quality through strategic negotiations and capacity management across...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by owning multi-year commodity strategies and leading global sourcing initiatives. Drive cost reduction and supplier performance while leveraging advanced AI for supply chain optimiza...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $252K *

Take ownership of strategic finance initiatives, driving growth through collaboration and analysis. Lead cross-functional teams to execute high-impact projects that align with organizational goals and...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Media

$110K *

Develop strong client relationships and drive revenue growth by managing the entire sales cycle, identifying expansion opportunities, and delivering tailored SaaS solutions to existing accounts in a f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Design scalable software solutions by transforming complex business needs into robust APIs and system architectures. Collaborate across teams to enhance reliability, mentor engineers, and drive techni...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Elevate training effectiveness by leading multi-domain intelligence support for ARNG units. Collaborate on exercise design, execution, and assessment while providing expert guidance and developing tra...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$193K - $285K *

Join a team that's redefining security engineering by designing and delivering innovative, multi-domain security services. Collaborate across teams to enhance physical and cloud security, ensuring ope...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $120K *

Champion operational excellence by transforming data into actionable insights, leading cross-functional projects, and driving process improvements to enhance performance and scalability in a dynamic e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$160K - $180K *

Lead the design and implementation of warehouse solutions, guiding teams through the Tecsys Elite WMS architecture. Drive integration, configuration, and continuous improvement while ensuring operatio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$100K - $150K *

Join our dynamic team as a Senior Engine Programmer, where you'll design and optimize core game engine systems, collaborating with external developers to enhance performance across multiple games. You...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$74K - $85K *

Lead the planning and execution of diverse research projects, ensuring alignment with organizational goals. Collaborate with stakeholders to manage timelines, deliverables, and budgets while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Unlock new business opportunities by building lasting client relationships, driving revenue growth, and expanding accounts in a dynamic field sales environment. Thrive in a role focused on face-to-fac...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$85K - $113K *

Unlock the potential of reinsurance accounting by ensuring accurate reporting and analysis. Collaborate with cross-functional teams to enhance processes, maintain compliance, and support financial int...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Drive growth by managing strategic enterprise accounts, cultivating relationships, and delivering tailored solutions that align with client objectives while exceeding sales targets and enhancing custo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $187K *

Transform public sector sales by driving growth strategies, building executive relationships, and leading complex pursuits. Leverage your expertise in IT consulting and digital transformation to close...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $95K *

Join a team that's dedicated to enhancing product learning experiences for credit unions and MAP employees. You'll design, develop, and deliver engaging training that empowers users to confidently ado...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in managing third-party risk programs, ensuring compliance and security through vendor assessments, collaboration with stakeholders, and maintaining governance standards across technol...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $125K *

Elevate the paper manufacturing sector by driving sales and fostering relationships with key accounts. Leverage your expertise to identify and implement effective chemical applications that enhance ef...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.