Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Global Product Line Manager - Modular
$176K - $243K *
Drive product portfolio expansion for Modular Datacenter Infrastructure, ensuring market leadership through strategic planning, P&L management, and fostering innovation. Lead a diverse team to enhance...
1 week ago
Sr. Manager, Real Estate, Tim Hortons, US
$110K - $130K *
Join a team that's shaping the future of restaurant development by partnering with franchisees to identify, secure, and build new locations. Drive growth through strategic site evaluations, negotiatio...
1 week ago
Senior Director, Global ERP Delivery & Solution Architecture
$151K - $314K *
Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...
1 week ago
Professional (Senior) Sales Representative, Respiratory – Southern IL
$100K - $162K *
Drive sales success in the Southern IL territory by developing strategic business plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals to achieve...
1 week ago
Professional (Senior) Sales Representative, Respiratory – The Woodlands, TX
$100K - $162K *
Drive success by developing strategic sales plans and fostering relationships in your territory. Achieve sales goals through effective presentations and ethical practices while continuously enhancing...
1 week ago
Professional (Senior) Sales Representative, Respiratory – Tulsa, OK
$100K - $162K *
Drive sales growth in assigned territory by developing strategic plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals while adhering to ethical p...
1 week ago
Director, Threat Detection & Response
$175K - $235K *
Accelerate progress at the forefront of cybersecurity by leading incident response, detection engineering, and threat hunting teams. Drive strategy and build capabilities to protect critical payment p...
1 week ago
Manager Pricing - Retail, Technology, Healthcare
$105K - $115K *
Lead financial pricing strategies and support sales operations through analytical insights, forecasting, and continuous improvement initiatives. Collaborate with cross-functional teams to optimize mar...
1 week ago
Environmental Services Manager
$85K - $95K *
Transform environmental compliance in supply chain services by managing assessments, audits, and training. Collaborate with stakeholders to ensure adherence to regulations and enhance operational effi...
1 week ago
$114K - $163K *
Empower beverage innovation by driving sales growth and strategic partnerships. Manage customer relationships, lead negotiations, and collaborate across teams to deliver tailored solutions in the alco...
1 week ago
Strategic Alliance Account Executive
$140K - $150K *
Champion strategic alliances by driving business development and managing key relationships within the Independent Financial Network, focusing on life insurance opportunities and enhancing market pres...
1 week ago
Senior Construction Specialist
$71K - $113K *
Join a team that's dedicated to managing specialty construction portfolios, ensuring compliance with lending policies, and guiding borrowers through the construction loan process while mitigating risk...
1 week ago
Senior Costpoint System Administrator
$110K - $130K *
Join a dynamic team as a Senior Costpoint System Administrator, overseeing Deltek Costpoint ERP management, ensuring system security, compliance, and seamless integrations while supporting finance and...
1 week ago
$100K - $120K *
Transform procurement operations by leading federal sourcing initiatives, ensuring compliance with regulations, and building audit-ready purchasing processes for a dynamic EPC contractor in the energy...
1 week ago
Award Transition Project Manager
$100K - $120K *
Champion seamless transitions by managing federal project awards from contract to construction. Collaborate with teams to ensure timely execution of all requirements, driving efficiency and clarity th...
1 week ago
Category Manager II / Senior Category Manager – MRO & Renewable Energy - EnergyLink
$110K - $130K *
Unlock potential by driving strategic sourcing for MRO and renewable energy projects. Collaborate with cross-functional teams to enhance supplier performance, optimize costs, and ensure material avail...
1 week ago
eDiscovery Managed Services Project Manager
$80K - $95K *
Champion superior client service by managing eDiscovery projects, coordinating teams, and strategizing solutions to meet client goals. Build strong relationships and ensure seamless communication betw...
1 week ago
Manager, People Analytics & Data Science
$128K - $252K *
Drive the evolution of people analytics by building data pipelines, dashboards, and insights that empower leaders with decision-ready information. Collaborate across teams to enhance data usability an...
1 week ago
People Ops Process Transformation Lead
$101K - $204K *
Unlock potential by leading the redesign of People Operations processes. Drive operational excellence through strategic assessments, workflow mapping, and implementation of innovative solutions that e...
1 week ago
$92K - $117K *
Join us to optimize AI support operations, enhancing member interactions through effective conversation design, automation, and workflow management. Collaborate across teams to ensure seamless integra...
1 week ago
Director, Automation Operations
$144K - $191K *
Unlock potential by leading the Automated Operations capability within Member Services. Oversee AI support experiences, enhance team productivity, and drive continuous improvement to elevate member in...
1 week ago
Senior Manager, Global Partner & Ecosystem Marketing
$120K - $145K *
Transform global partner marketing strategies to drive growth and engagement. Collaborate with cross-functional teams to execute integrated campaigns and optimize performance across diverse markets, e...
1 week ago
$182K - $198K *
Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...
1 week ago
Test Lead II - Healthcare Payer Testing
$90K - $120K *
Champion quality assurance in healthcare payer systems by leading test planning, execution, and defect management. Collaborate with cross-functional teams to ensure compliance and deliver high-quality...
1 week ago
Healthcare IT Technical Operations Lead (Edifecs)
$90K - $120K *
Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.