Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Senior Oncology Account Manager, Boston South
$150K - $230K *
Champion your career by driving oncology product success and building impactful relationships with healthcare professionals. Leverage your expertise to enhance patient access and deliver innovative so...
1 week ago
Senior Oncology Account Manager, Orange County
$150K - $230K *
Champion the promotion of oncology products, building strong relationships with healthcare stakeholders while driving performance goals and ensuring patient access to innovative therapies in a dynamic...
1 week ago
Senior Oncology Account Manager, Milwaukee
$150K - $230K *
Join a team that's dedicated to advancing oncology care by promoting innovative products and building strong relationships with healthcare professionals. Leverage your expertise to drive brand value a...
1 week ago
Senior Oncology Account Manager, Philadelphia
$150K - $230K *
Drive impactful oncology solutions by building relationships with key stakeholders. Leverage your expertise to exceed performance goals and enhance patient access to innovative therapies while managin...
1 week ago
Senior Oncology Account Manager, Cleveland
$150K - $230K *
Drive impactful oncology product promotion by building strong relationships with key stakeholders. Leverage clinical expertise and market insights to exceed performance goals while ensuring patient ac...
1 week ago
Senior Oncology Account Manager, Charlotte
$150K - $230K *
Empower your career by driving oncology product success through strategic relationships and innovative solutions. Lead market engagement, exceed performance goals, and enhance patient access while col...
1 week ago
Senior Oncology Account Manager, Omaha
$150K - $230K *
Transform the future of oncology care by driving product success and building strong relationships with key stakeholders. Lead initiatives that enhance patient access and deliver innovative solutions...
1 week ago
Senior Oncology Account Manager, Des Moines
$150K - $230K *
Champion the promotion of oncology products, building strong relationships with healthcare professionals to enhance patient access and drive brand value in a competitive market. Lead strategic initiat...
1 week ago
$73K - $102K *
Drive innovative SAP solutions by developing and implementing Fiori applications, enhancing ABAP capabilities, and collaborating with teams to meet client needs in a dynamic environment...
1 week ago
$110K - $130K *
Transform KYC operations by leading a team focused on customer onboarding and due diligence. Drive policy ownership, manage complex cases, and enhance processes through collaboration with cross-functi...
1 week ago
Senior Architect, Professional Services
$170K - $220K *
Shape the future of customer solutions by leading implementations and driving adoption of innovative technologies. Collaborate with teams to deliver tailored architectural designs that meet strategic...
1 week ago
$125K - $155K *
Grow your career with a dynamic team focused on designing and implementing scalable systems. Collaborate on complex projects, mentor peers, and drive technical excellence while contributing to impactf...
1 week ago
$128K - $188K *
Transform strategic growth initiatives by partnering with executives to solve complex challenges, drive alignment across teams, and enhance customer experiences in a fast-paced communications and AI l...
1 week ago
Managing Consultant- Infrastructure Resilience
$118K - $196K *
Transform client outcomes through innovative problem-solving and project management in power systems consulting. Engage in impactful research and data analysis to enhance climate resilience and sustai...
Reposted 1 week ago
$194K - $285K *
Innovate in the credit space by leading a dynamic underwriting team. Drive strategy, mentor talent, and establish best-in-class credit programs while collaborating with internal and external partners...
1 week ago
$229K - $458K *
Champion strategic growth initiatives in advanced manufacturing, driving business development and forging key partnerships. Collaborate with cross-functional teams to enhance service offerings and mee...
1 week ago
Director, Commercial Legal, Americas
$241K - $448K *
Drive the Americas Commercial Legal team, leading negotiations on complex software agreements while fostering collaboration and developing talent. Engage with stakeholders to ensure legal alignment an...
1 week ago
$90K - $141K *
Champion patient care by leading a dedicated team in an outpatient clinic. Drive operational excellence, enhance patient relationships, and foster a culture of growth while managing clinic performance...
1 week ago
$105K - $125K *
Transform coding quality and efficiency as a senior expert in radiology coding. Collaborate with cross-functional teams to enhance processes, provide guidance, and drive best practices, ensuring excep...
1 week ago
Senior Oncology Account Manager, San Diego
$150K - $230K *
Transform oncology care by driving product adoption and building relationships with key stakeholders. Leverage your expertise to exceed performance goals and ensure patient access to innovative therap...
1 week ago
Senior Oncology Account Manager, New Haven
$150K - $230K *
Transform the oncology landscape by driving product success and building strong relationships with key stakeholders. Leverage your expertise to enhance patient access and deliver innovative solutions...
1 week ago
Director, Public Sector Channels
$180K - $200K *
Join a dynamic team as a strategic leader to drive the public sector channel strategy, focusing on the U.S. federal market. Build relationships, execute go-to-market plans, and empower partners to del...
1 week ago
$135K - $160K *
Transform our growth marketing strategy by driving demand generation and managing a high-performing team. Collaborate with cross-functional leaders to optimize pipeline performance and leverage automa...
1 week ago
$171K - $192K *
Unlock potential by pursuing named NeoCloud accounts, building relationships, and driving complex sales from initial contact to contract. Collaborate with technical teams to deliver tailored solutions...
1 week ago
Associate General Counsel - Product - Partnerships
$160K - $200K *
Lead the charge in shaping legal strategies for innovative technology products. Collaborate with cross-functional teams to provide expert legal guidance throughout the product lifecycle, ensuring comp...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.