Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$135K - $185K *

Transform enterprise architecture by defining our technology strategy, guiding scalable solutions, and leading modernization initiatives that align with business goals. Thrive in a role that fosters i...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Transportation

$160K - $200K *

Take ownership of transformative initiatives in higher education, serving as a trusted expert and strategic advisor. Drive top-of-funnel growth, enhance institutional partnerships, and elevate academi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on mid-sized public safety agencies. Drive recruitment, coaching, and team success while leveraging AI tools to enhance sales strateg...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$115K - $160K *

Champion member engagement by crafting compelling campaigns that drive awareness and action. Collaborate across teams to enhance communication, utilizing AI tools to optimize outreach and improve memb...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate demo quality by owning and customizing demo environments, ensuring they are reliable and tailored for the go-to-market team. Collaborate with cross-functional teams to enhance demo readiness a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$106K - $130K *

Join a dynamic team as you lead distributor strategies and drive sales growth across South Texas, Louisiana, and Mississippi. Collaborate cross-functionally to optimize performance and ensure successf...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$135K - $160K *

Shape the future of geospatial science by leading the design and development of innovative data processing pipelines and APIs, while mentoring engineers and setting technical direction in a dynamic, m...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $90K *

Join a team that's dedicated to financial integrity while enabling global access to safe water. As a key player in consolidated reporting, you will enhance organizational clarity and support impactful...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$78K - $119K *

Unlock potential by managing complex workers' compensation claims, driving investigations, and shaping strategies. Build relationships, ensure compliance, and mentor others while making a direct impac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$86K - $138K *

Champion financial analysis and reporting by conducting in-depth research, preparing forecasts, and collaborating across departments to enhance decision-making and drive business success...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$227K - $385K *

Elevate member care by overseeing utilization management and evaluating treatment appropriateness. Collaborate with multidisciplinary teams, ensuring compliance with clinical standards and regulations...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $146K *

Drive excellence at the forefront of demand planning and forecasting. Lead a dynamic team to refine processes, enhance accuracy, and foster data-driven strategies that align with business goals and im...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Empower revenue operations by architecting and optimizing scalable GTM systems. Collaborate with cross-functional teams to translate complex business needs into automated solutions, ensuring seamless...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $125K *

Empower your career by driving growth in the Fiberglass Pools market. In this dynamic sales role, you'll identify new business opportunities, expand market presence, and achieve sales targets while co...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$175K - $190K *

Shape the future of ERP and Finance transformation by guiding clients through strategic assessments, technology alignment, and implementation execution, leveraging your Oracle Finance expertise to dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $120K *

Unlock your potential by leading operational excellence in training programs. Drive performance, streamline processes, and enhance client experiences in a dynamic, remote environment. Collaborate acro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$150K - $200K *

Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $267K *

Transform safety enforcement through data science by developing models and systems that detect and mitigate abuse. Collaborate across teams to translate policies into actionable insights, ensuring eff...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$120K - $170K *

Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$66K - $99K *

Play a key role in delivering exceptional outpatient nursing care by assessing, planning, and implementing individualized patient care in collaboration with a multidisciplinary team, ensuring adherenc...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive the branded merchandise function, overseeing vendor sourcing, production management, and budget accountability. Ensure timely delivery and quality control while collaborating cross-functionally...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Lead the charge in driving regional sales growth by developing strategic plans, managing budgets, and fostering strong customer relationships. Collaborate with cross-functional teams to optimize perfo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$75K - $110K *

Optimize the claims resolution process for commercial property and casualty claims. Collaborate with internal teams and stakeholders to enhance claims handling efficiency and effective communication...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$128K - $177K *

Innovate solutions as a System Architect, leading design and implementation of ASTRO systems. Collaborate with cross-functional teams to enhance communication technologies, ensuring seamless integrati...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.