Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$73K - $88K *

Accelerate progress at expanding customer accounts by driving annual recurring revenue and enhancing retention through structured sales strategies and digital engagement, while managing a high-volume...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$170K - $220K *

Unlock potential by leading the integration of AI tools with PlanetScale databases. Own the developer experience, ensuring seamless functionality across platforms while creating engaging content to sh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$112K - $150K *

Drive impactful research and project management initiatives focused on AI's labor and economic effects. Collaborate with diverse stakeholders to develop a comprehensive research agenda and deliver act...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$181K - $245K *

Elevate your career by leading lifecycle marketing strategies that enhance customer engagement, retention, and monetization. Drive impactful programs while managing a high-performing team and collabor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $95K *

Champion faculty success by developing and delivering innovative professional learning programs. Collaborate with stakeholders to enhance instructional quality and faculty engagement while ensuring al...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$127K - $157K *

Join a team that's redefining healthcare quality by owning HEDIS performance measures. You'll design and implement impactful programs, collaborate across teams, and drive improvements to enhance patie...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading IT operations and identity management, transforming strategy into action. Drive technical excellence in Microsoft Entra ID, endpoint platforms, and SaaS integrations while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Elevate your career by joining a dynamic team focused on transforming corporate learning. As a senior leader, you'll drive strategic initiatives, engage with top executives, and shape the future of wo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $185K *

Lead the charge in overseeing the commissioning of electrical substations, ensuring operational excellence and compliance with industry standards. Collaborate with teams, manage projects, and build cl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$131K - $190K *

Lead strategic initiatives that enhance customer engagement and drive actionable insights. Collaborate cross-functionally to improve processes, connect feedback to decisions, and advance customer expe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$182K - $212K *

Lead quality assurance efforts in rolling stock engineering, overseeing vehicle procurement and rebuilds. Collaborate with teams to ensure high standards and timely delivery while supervising inspecti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$220K - $240K *

Drive strategic growth and operational excellence in a B2B SaaS environment, overseeing P&L, leading a diverse team, and integrating scalable subscription models with custom enterprise solutions to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Join a team that's redefining product management by building innovative features from concept to launch. Leverage AI tools to enhance efficiency and drive product operations, ensuring seamless deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $105K *

Unlock potential by providing strategic technical support to enhance retrofit sales. Collaborate with sales teams and end-users to optimize HVAC systems, identify improvement opportunities, and drive...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Drive market and competitive intelligence initiatives to enhance strategic decision-making across teams. Build a high-performing function that delivers insights on customer behavior, market trends, an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $135K *

Lead the charge in developing and implementing global safety standards and compliance initiatives. Collaborate with cross-functional teams to foster a proactive safety culture, ensuring the health and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$95K - $140K *

Engage with clients to optimize their cybersecurity services investment, ensuring success through strategic relationship management, education, and program enhancement. Drive customer preparedness and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by leveraging your Salesforce expertise to design, build, and review secure, scalable solutions. Collaborate with clients and teams to ensure seamless integrations and effective deliv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $94K *

Unlock potential by joining a dynamic team that supports military transitions into civilian roles. Gain hands-on experience in IT project management while collaborating with industry leaders to enhanc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$190K - $200K *

Elevate operational excellence by leading transformation initiatives and optimizing Shared Services. Collaborate with senior leaders to drive measurable improvements in productivity, cost efficiency...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$119K - $140K *

Drive global marketing strategy by executing integrated campaigns that enhance revenue through collaboration with cross-functional teams, while optimizing performance with data-driven approaches to ma...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $105K *

Optimize software quality by collaborating with cross-functional teams to ensure seamless digital experiences. Leverage automation and modern testing practices to enhance web and mobile applications f...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Empower innovation by partnering with data science to build and maintain robust ML pipelines. Drive automation and observability in production systems, ensuring reliable match data at scale while coll...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.