Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Commerce Media Strategist, Amazon DSP (Full Funnel)
$80K - $95K *
Elevate client success by crafting and optimizing innovative commerce media strategies. Leverage data-driven insights to enhance campaign performance across platforms, ensuring measurable growth and c...
6 days ago
Senior Manager, Partner Brand Strategy
$110K - $130K *
Champion brand strategy for a diverse portfolio of university partners. Lead a team to develop positioning, messaging, and creative briefs, ensuring alignment across marketing functions while leveragi...
6 days ago
Director Advisory Services Analytics Delivery and Data Engineering
$141K - $234K *
Lead the charge in healthcare performance improvement by overseeing project delivery, managing client relationships, and mentoring a team of Advisory consultants to ensure successful, high-quality out...
Reposted 6 days ago
Vice President, Revenue Cycle Management
$202K - $250K *
Elevate the Personal Care department by driving strategic billing and claims initiatives, optimizing processes for accuracy and compliance, and leading a high-performing team to achieve operational ex...
6 days ago
Claims Configuration Senior Manager
$110K - $150K *
Unlock potential by leading claims adjudication logic to enhance accuracy and efficiency. Drive strategic improvements, collaborate across teams, and ensure compliance while optimizing operations in a...
6 days ago
Claims Compliance Program Manager
$73K - $130K *
Lead the charge in overseeing claims compliance activities, enhancing operational quality, and ensuring audit readiness. Collaborate cross-functionally to identify gaps, monitor KPIs, and drive improv...
6 days ago
Workday Integrations Consultant (currently Workday Integrations or Studio certified required)
$88K - $163K *
Help us optimize Workday integrations by configuring, testing, and delivering high-quality solutions across multiple projects. Collaborate with clients and teams to enhance processes and deepen your e...
6 days ago
Channel Sales Representative, Microsoft Teams Voice
$162K - $244K *
Join a team that's driving channel success by building strong partnerships, creating impactful business plans, and enhancing pipeline growth through strategic collaboration and support for regional pa...
6 days ago
Senior Supplier Quality Engineer
$116K - $154K *
Bring your expertise to drive supplier quality excellence, implementing quality plans, managing audits, and fostering improvements. Collaborate with engineering teams to enhance manufacturability and...
6 days ago
Associate Director Of Brand Activation & Content
$120K - $145K *
Lead the charge in defining and activating brand strategies across multiple channels, enhancing donor engagement and retention through innovative content and social communications while collaborating...
6 days ago
Sr. Principal Contract Negotiation Analyst
$106K - $160K *
Lead complex contract negotiations and drive strategic supplier relationships. Collaborate with stakeholders to assess risks, develop negotiation strategies, and enhance contracting practices while me...
6 days ago
Clinical Applications Pharmacist
$95K - $115K *
Join our team to enhance clinical systems for medication management, focusing on optimizing workflows and supporting pharmacy operations. Collaborate with stakeholders to ensure accuracy and efficienc...
6 days ago
Technical Specialist - Embedded QT
$168K - $231K *
Unlock potential by leading the design and development of innovative software solutions for medical devices. Collaborate with cross-functional teams to ensure high-quality, secure software that enhanc...
6 days ago
$63K - $129K *
Shape your career by driving Agile execution excellence in federal HCM modernization. Lead cross-functional teams, facilitate SAFe ceremonies, and foster a continuous improvement culture within a larg...
Reposted 6 days ago
SME Software Developer - REMOTE
$114K - $252K *
Unlock potential by leading software development initiatives, ensuring system integration, and guiding teams through agile methodologies to deliver high-quality solutions that meet customer requiremen...
6 days ago
Regulatory Submissions Lead II
$110K - $130K *
Lead and execute regulatory strategies for multi-region clinical trials, ensuring compliance and timely submissions. Collaborate with project teams to manage risks and drive operational excellence thr...
6 days ago
Lead Mechanical Engineer 1 - Nuclear Plant Analysis
$118K - $180K *
Join a dynamic team enhancing nuclear power plants through advanced engineering. Leverage your expertise in thermodynamics and fluid mechanics to drive power uprate projects, mentor junior staff, and...
6 days ago
Senior Air Permitting Specialist
$100K - $152K *
Empower progress in environmental compliance by developing air permitting strategies for complex industrial projects. Collaborate with multi-disciplined teams to ensure adherence to air quality regula...
6 days ago
Structural Engineering Consultant 2 - Nuclear
$145K - $222K *
Lead a structural engineering team, guiding projects for nuclear facilities. Utilize your expertise in design and analysis while collaborating with clients and multidisciplinary teams to deliver innov...
6 days ago
Project Management Technical Director - Northern/Central California
$132K - $174K *
Shape the future of environmental consulting by leading complex projects, fostering client relationships, and driving strategic initiatives. Collaborate with multidisciplinary teams to ensure excellen...
6 days ago
$110K - $130K *
Elevate product execution by translating client needs into actionable requirements, collaborating with engineering and data science teams to deliver standardized measurement solutions across various c...
6 days ago
$89K - $113K *
Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...
6 days ago
Manager of Clinical Engagement
$115K - $130K *
Join a team that's redefining clinical engagement by leading strategic initiatives to enhance clinician pipelines, improve hiring processes, and foster partnerships across multiple regions, driving or...
1 week ago
Senior Product Marketing Manager, Risk Advisory
$125K - $150K *
Shape the future of product marketing by bridging product and go-to-market teams. Drive impactful messaging, enablement, and strategies that resonate with audiences, ensuring alignment in a fast-paced...
1 week ago
$115K - $150K *
Architect and streamline cloud network infrastructure. Support robust security and connectivity across Azure, OpenShift, and SASE platforms. Collaborate with cross-functional teams, ensuring optimal p...
Reposted 1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.