Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Workday Functional Consultant (PATT)
$90K - $190K *
Unlock potential by serving as a functional SME in Workday solutions, advising and configuring systems to meet client needs. Balance multiple projects while ensuring timely issue resolution and delive...
5 days ago
$90K - $110K *
Join our new Data Engineering team to lead business intelligence initiatives, build trusted data models in Snowflake, and deliver impactful reports in Power BI. Collaborate with stakeholders to enhanc...
5 days ago
$100K - $120K *
Champion endpoint strategy and governance, leading a specialized team to deliver secure, scalable services across diverse devices. Collaborate with IT and business leaders to drive automation, operati...
5 days ago
Corporate Sales Engineer, Customer Sales (Remote)
$75K - $115K *
Innovate in cybersecurity as you drive technical conversations and deliver tailored solutions. Collaborate with sales teams to enhance customer relationships and showcase the unique value of next-gen...
5 days ago
Specialist, Cloud Security (Remote)
$85K - $128K *
Unlock potential by driving cloud security sales initiatives, collaborating with teams, establishing partnerships with key personas, and engaging customers to integrate innovative security solutions i...
Reposted 5 days ago
Manager, Platform Services Project Management (Remote)
$140K - $195K *
Transform project delivery by leading a team of Project Managers to ensure timely, budget-conscious deployment of customer projects while enhancing processes and driving efficiency across cross-functi...
5 days ago
Automation Engineer (Cisco CNC Upgrade)
$77K - $118K *
Transform network operations by designing and implementing automation solutions that enhance reliability and efficiency across multi-vendor infrastructures, utilizing advanced technologies like Python...
Reposted 5 days ago
$77K - $118K *
Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...
Reposted 5 days ago
Director, Global Transfer Pricing
$174K - $234K *
Champion the development and governance of global transfer pricing strategies, ensuring alignment with business operations and compliance across jurisdictions while leading cross-functional collaborat...
5 days ago
Senior Director, Regulatory Affairs, CMC
$204K - $274K *
Champion the U.S. Biologics Regulatory CMC team by providing strategic leadership, ensuring timely regulatory submissions, and fostering collaboration among global stakeholders to drive innovative bio...
Reposted 5 days ago
Thought Leader Liaison, US Oncology, South
$167K - $300K *
Unlock your potential by leading regional oncology thought leader engagement and advocacy strategies. Collaborate with cross-functional teams to shape brand strategy and launch planning for innovative...
5 days ago
Thought Leader Liaison, US Oncology, Northeast
$167K - $300K *
Elevate oncology marketing strategies by leading KOL engagement and advocacy initiatives. Utilize market insights to shape brand strategy and launch planning for innovative therapies, ensuring complia...
5 days ago
Thought Leader Liaison, US Oncology, Central
$167K - $300K *
Lead the charge in transforming cancer treatment through strategic KOL engagement and advocacy. Drive regional initiatives, leveraging market insights to shape brand strategy and launch planning for i...
5 days ago
Thought Leader Liaison, US Oncology, West
$167K - $300K *
Lead the charge in oncology marketing by developing KOL engagement strategies and insights for individualized therapies. Collaborate cross-functionally to drive brand strategy and launch planning, ens...
5 days ago
Senior Analyst Treasury Cash Forecasting & Analysis
$79K - $112K *
Transform cash forecasting processes by leveraging technology and analytics. Collaborate with Treasury leadership to enhance cash flow insights and automate reporting, ensuring accuracy and efficiency...
5 days ago
Assistant Director, Supervision
$127K - $171K *
Lead a dynamic team in overseeing compliance and supervision for securities and investment advisers. Drive risk mitigation strategies, enhance supervisory frameworks, and collaborate with cross-functi...
5 days ago
$137K - $185K *
Drive the execution of complex projects, ensuring alignment across global teams. Collaborate with stakeholders to manage risks, track progress, and deliver key medical strategies while fostering cross...
5 days ago
$120K - $145K *
Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...
5 days ago
$90K - $110K *
Lead a dynamic sales team to drive growth and enhance customer relationships. Foster a culture of accountability and collaboration while implementing strategic sales initiatives that support profitabi...
5 days ago
$125K - $150K *
Shape the future of marketing by leading strategy and execution in a dynamic B2B SaaS environment. Collaborate closely with leadership to drive pipeline growth and create compelling narratives that re...
5 days ago
Sr Manager, Data Process Excellence & Transformation
$115K - $192K *
Elevate operational excellence by leading process design and transformation initiatives. Drive automation, quality management, and continuous improvement to enhance client data operations and ensure s...
Reposted 5 days ago
Senior Scientist, Safety Assessment and Investigative Toxicology
$66K - $189K *
Innovate analytical strategies to enhance toxicology assessments, ensuring compliance and data integrity. Collaborate across teams to drive project success and influence decision-making through advanc...
5 days ago
Manager, Dispatch Follow Up (Cox Fleet)
$81K - $122K *
Transform fleet operations by leading a dynamic dispatch team, ensuring exceptional service delivery and operational excellence while fostering team development and customer satisfaction in a fast-pac...
5 days ago
$140K - $180K *
Shape the future of our iOS platform by designing and implementing scalable features. Collaborate with cross-functional teams to deliver innovative solutions that enhance client interactions with emis...
5 days ago
Sales & Client Success Strategic Account Manager (Mortgage)
$148K - $233K *
Engage with US mortgage lenders to drive adoption of FICO's credit analytics and services. Lead initiatives to maximize revenue opportunities and enhance client experiences while providing strategic i...
Reposted 5 days ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.