Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Project Manager - AEC / MEP / Engineering
$90K - $130K *
Join a team that's driving large-scale infrastructure projects. As a Project Manager, you'll lead initiatives from kickoff to closeout, ensuring alignment with program objectives and stakeholder expec...
4 days ago
$90K - $117K *
Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...
4 days ago
$128K - $250K *
Innovate enterprise sales by leading the strategy for large deal pursuits, engaging C-suite clients, and delivering transformative solutions in retail and logistics sectors...
Reposted 4 days ago
$125K - $145K *
Lead campaign strategy and execution for oncology pharma marketing, driving performance optimization and cross-functional collaboration. Own end-to-end campaign management, ensuring alignment with bus...
Reposted 4 days ago
$170K - $220K *
Lead the charge in providing comprehensive legal support for the CHVAC segment, collaborating with global teams to ensure compliance and address complex legal matters while driving strategic initiativ...
4 days ago
$135K - $160K *
Lead the charge in quality and validation readiness for complex programs, uniting Engineering, Product, and Customer Success teams. Utilize AI and automation to streamline processes, enhance delivery...
4 days ago
Account Executive, HME Provider Sales
$80K - $100K *
Join a team that's driving growth by acquiring new customers and enhancing revenue through innovative solutions. Manage the full sales cycle while collaborating with cross-functional teams to ensure e...
4 days ago
Revenue Enablement Program Manager II
$91K *
Champion cross-functional programs that drive strategic outcomes, ensuring alignment with organizational priorities. Lead complex initiatives, manage risks, and foster stakeholder engagement to delive...
4 days ago
Medical Director, Post Acute Care
$207K - $346K *
Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...
Reposted 4 days ago
Electrical Manager MV - 100% Travel
$100K - $120K *
Transform the future of utility-scale solar projects by leading electrical operations, ensuring quality installations, and fostering strong team collaboration while managing contractor activities and...
4 days ago
$91K - $115K *
Transform the candidate experience by sourcing top talent for sales and corporate roles. Collaborate with recruiters and hiring managers to build pipelines, utilizing advanced sourcing techniques and...
4 days ago
Product Owner, AI & AWS Delivery
$110K - $130K *
Drive impactful AI and Agentforce delivery projects, managing customer relationships and internal initiatives. Leverage your strategic planning and analytical skills to oversee project execution and f...
4 days ago
$210K - $260K *
Elevate IT operations by leading system integration and security strategy. Own the full tech stack, streamline processes, and enhance patient care through automation and effective team management in a...
4 days ago
$95K - $115K *
Optimize patient access workflows by aligning registration with revenue cycle needs. Collaborate with stakeholders to enhance eligibility processes and improve patient estimates, while mentoring IS st...
4 days ago
$210K - $260K *
Transform the workplace culture and integration of two organizations, ensuring support for clinicians and staff while enhancing benefits, compensation, and recruitment strategies to foster a unified m...
4 days ago
$103K - $176K *
Transform downstream marketing for cutting-edge medical devices. Drive product launches, develop compelling content, analyze market trends, and ensure regulatory compliance across global regions while...
Reposted 4 days ago
Power Systems Study Engineer III
$104K - $130K *
Unlock potential by guiding complex power system studies for mission critical facilities. Collaborate with designers, manage projects independently, and leverage advanced technologies to enhance opera...
Reposted 4 days ago
$150K - $180K *
Accelerate growth by leading global partnerships with PwC and GSIs. Drive revenue through strategic relationship management, co-selling initiatives, and market expansion while collaborating with cross...
4 days ago
Senior Business Applications Engineer
$150K - $200K *
Lead the charge in transforming business challenges into innovative solutions by leveraging your expertise in automation and integration. Collaborate across teams to enhance operational efficiency and...
4 days ago
Senior Manager, Finance Analytics
$175K - $185K *
Join a team that's redefining finance analytics by leading strategic forecasting and performance management. Drive impactful financial insights and methodologies while collaborating with leadership to...
4 days ago
Associate Director, Paid Social
$96K - $135K *
Elevate your career as a strategic leader in paid social, driving growth through innovative strategies and high-performing teams. Leverage your expertise to optimize complex campaigns and foster colla...
4 days ago
$98K - $126K *
Empower customer success by managing renewals, driving growth, and mitigating risks. Collaborate with cross-functional teams to enhance client relationships and ensure satisfaction while maximizing co...
4 days ago
Senior Tax Associate, Indirect Sales and Use
$85K - $100K *
Join a team that's dedicated to delivering exceptional indirect tax solutions. You'll manage compliance, conduct research, and collaborate with clients across multiple jurisdictions, enhancing their t...
4 days ago
Renewables Civil Designer-BESS
$79K - $107K *
Join a team that's redefining energy solutions by designing innovative Battery Energy Storage Systems. Collaborate with engineers to deliver impactful civil designs that enhance land development proje...
4 days ago
Strategy & Operations Senior Manager (Security and Technology)
$200K - $235K *
Empower organizational strategy and execution in Security & Technology, driving cross-functional initiatives and enhancing communication. Collaborate with leadership to optimize operations and inspire...
4 days ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.