Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$110K - $130K *

Drive impactful AI and Agentforce delivery projects, managing customer relationships and internal initiatives. Leverage your strategic planning and analytical skills to oversee project execution and f...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$210K - $260K *

Elevate IT operations by leading system integration and security strategy. Own the full tech stack, streamline processes, and enhance patient care through automation and effective team management in a...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize patient access workflows by aligning registration with revenue cycle needs. Collaborate with stakeholders to enhance eligibility processes and improve patient estimates, while mentoring IS st...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $260K *

Transform the workplace culture and integration of two organizations, ensuring support for clinicians and staff while enhancing benefits, compensation, and recruitment strategies to foster a unified m...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $176K *

Transform downstream marketing for cutting-edge medical devices. Drive product launches, develop compelling content, analyze market trends, and ensure regulatory compliance across global regions while...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $130K *

Unlock potential by guiding complex power system studies for mission critical facilities. Collaborate with designers, manage projects independently, and leverage advanced technologies to enhance opera...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $180K *

Accelerate growth by leading global partnerships with PwC and GSIs. Drive revenue through strategic relationship management, co-selling initiatives, and market expansion while collaborating with cross...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $200K *

Lead the charge in transforming business challenges into innovative solutions by leveraging your expertise in automation and integration. Collaborate across teams to enhance operational efficiency and...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $185K *

Join a team that's redefining finance analytics by leading strategic forecasting and performance management. Drive impactful financial insights and methodologies while collaborating with leadership to...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$96K - $135K *

Elevate your career as a strategic leader in paid social, driving growth through innovative strategies and high-performing teams. Leverage your expertise to optimize complex campaigns and foster colla...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Media

$98K - $126K *

Empower customer success by managing renewals, driving growth, and mitigating risks. Collaborate with cross-functional teams to enhance client relationships and ensure satisfaction while maximizing co...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$85K - $100K *

Join a team that's dedicated to delivering exceptional indirect tax solutions. You'll manage compliance, conduct research, and collaborate with clients across multiple jurisdictions, enhancing their t...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$79K - $107K *

Join a team that's redefining energy solutions by designing innovative Battery Energy Storage Systems. Collaborate with engineers to deliver impactful civil designs that enhance land development proje...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$200K - $235K *

Empower organizational strategy and execution in Security & Technology, driving cross-functional initiatives and enhancing communication. Collaborate with leadership to optimize operations and inspire...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$199K - $274K *

Transform enterprise-scale engineering capabilities by leading the TORC function, fostering collaboration across security and operations, and delivering innovative solutions for risk and control manag...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$160K - $180K *

Lead the charge in strategic ERP advisory engagements, guiding clients through enterprise transformation and technology alignment to drive impactful change and enhance organizational readiness across...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$240K - $260K *

Elevate your career by leading utility-scale solar PV and BESS projects. Drive growth, foster partnerships, and enhance project delivery through strategic leadership and operational excellence across...

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $150K *

Shape the future of safety in a dynamic environment by developing and enhancing EHS programs. Collaborate across teams to foster a culture of safety and compliance, ensuring adherence to regulations w...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $145K *

Shape the future of healthcare technology by designing and implementing innovative care management tools. Collaborate with teams to create reliable software solutions while mentoring others and advanc...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $100K *

Innovate user experiences by managing and enhancing the Salesforce platform. Collaborate with stakeholders to translate business needs into effective solutions, ensuring data quality and user adoption...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Transform our web presence by owning strategy and optimization across multiple domains, enhancing user engagement, driving conversions, and managing a high-performing team to create a seamless and eff...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Staffing

$192K - $229K *

Lead the charge in delivering comprehensive data migration services for SAP-enabled transformations, ensuring effective governance, client engagement, and execution of best practices across diverse da...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$197K - $232K *

Lead growth in a dynamic sales team focused on enterprise accounts, driving execution and collaboration to enhance market reach and customer relationships. Shape strategy and sales processes while bui...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive automated security solutions by designing and implementing Super Intelligence capabilities, enhancing threat detection and response across integrated security technologies while collaborating wi...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$170K *

Join our Retail Enterprise team to drive sales growth by building strong customer relationships and delivering tailored software solutions. Utilize consultative selling skills to meet business objecti...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.