Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$180K *

Transform technical solutions for Federal proposals by leading innovative strategies, collaborating with stakeholders, and ensuring compliance. Drive success through expert writing and systems enginee...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$105K - $211K *

Elevate your sales career by driving full-cycle sales for innovative solutions. Build strong pipelines, engage with clients, and collaborate cross-functionally to enhance customer experiences and achi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$92K - $184K *

Elevate your sales career by driving full-cycle sales for innovative solutions. Build strong pipelines, engage with clients, and collaborate cross-functionally to enhance customer experiences and achi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$73K - $138K *

Drive supplier sourcing and management for critical Aeronautics Systems programs, ensuring timely, cost-effective delivery of materials and services while collaborating internally to enhance efficienc...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $162K *

Shape the future of automotive marketing by leading OEM strategies that drive sales, service, and customer engagement. Collaborate with cross-functional teams to optimize performance and ensure alignm...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$105K - $231K *

Transform procurement processes by configuring SAP S/4HANA PTP/MM, supporting end-to-end lifecycle management, and collaborating with stakeholders to enhance operational efficiency and system performa...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$68K - $143K *

Join us to enhance business processes through analysis and reengineering, collaborating with stakeholders to ensure effective solutions and implementation. Drive efficiency and innovation in transport...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Optimize SAP environments by administering S/4HANA systems, ensuring stability and performance. Collaborate across teams to lead upgrades and cloud transitions, enhancing enterprise resilience and sup...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$63K - $129K *

Join a dynamic team to support lifecycle management for Military Sealift Command ships, focusing on long-term maintenance and operational planning while ensuring compliance with engineering standards...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$149K - $171K *

Pioneer strategic partnerships in luxury travel, driving growth and innovation. Lead negotiations, enhance customer value, and collaborate across teams to optimize Capital One Travel's offerings and e...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$50K - $500K *

Deliver safe and efficient operations as a Falcon 2000LX Captain, ensuring compliance with regulations and company policies while providing exceptional service to clients and maintaining a culture of...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Lead feasibility strategy and execution for clinical studies, driving operational excellence and data-driven insights to optimize trial planning and enrollment across rare disease programs. Collaborat...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $135K *

Join a team that's driving enterprise growth by identifying new business opportunities and forming strategic relationships. You'll navigate complex sales cycles and engage with senior leaders to tailo...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Drive integrated marketing strategies for Enterprise accounts, enhancing engagement and pipeline growth. Collaborate with sales teams to execute targeted campaigns and impactful events, optimizing per...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Champion the delivery of large-scale data center projects, overseeing field operations, client coordination, and compliance across multiple sites. Drive project success through effective management of...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Lead the consolidation of financial models and metrics, partnering with cross-functional teams to deliver actionable insights and support strategic decision-making across the organization...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $151K *

Transform technology operations by leading financial management, procurement, vendor oversight, and asset management. Drive strategic decision-making and operational excellence to enhance service deli...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$96K - $135K *

Champion process automation and enhancements by leading investment initiatives, mentoring teams, and collaborating across departments to drive efficiency and continuous improvement in investment servi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$163K - $192K *

Lead the charge in enhancing hotel performance and franchisee support by managing teams, driving operational excellence, and activating commercial strategies across the Core portfolio, ensuring alignm...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$100K - $162K *

Join us to develop strategic business plans and conduct effective sales presentations while achieving goals in the pharmaceutical territory. Build relationships, influence key stakeholders, and drive...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Engage with healthcare professionals to drive sales growth in the Cape Coral territory. Develop strategic business plans, conduct impactful presentations, and foster strong relationships while adherin...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Analyze energy efficiency and demand response programs while collaborating with a diverse team. Utilize data analysis to provide insights, recommendations, and drive improvements for utilities across...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$111K - $160K *

Transform category growth by leveraging insights and strategies to enhance customer performance. Collaborate cross-functionally to optimize assortments and drive sales initiatives across diverse retai...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Deliver strategic solutions to state and local governments, enhancing disaster preparedness and recovery. Manage relationships, navigate procurement, and drive sales cycles while collaborating with di...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Elevate integrations by leading the product roadmap, focusing on API-first solutions and enhancing developer experience to drive scalability and monetization across the platform...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.