Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Enterprise Account Executive, North America
$150K - $180K *
Unlock your potential by driving new-logo acquisition in a competitive enterprise market. Engage with senior decision-makers, develop strategic relationships, and build a robust pipeline to achieve am...
3 days ago
Sales Director, Electric Meters - North Central (Remote)
$125K - $150K *
Elevate your career by driving innovative sales strategies within the utility sector. This leadership role empowers you to expand Aclara's electric meter solutions across a dynamic region, fostering k...
Reposted 3 days ago
Strategic Customer Success Manager, Exteriors
$111K - $167K *
Elevate customer success by owning strategic relationships and technical solutions. Drive adoption and outcomes for a portfolio of accounts, collaborating across teams to ensure seamless implementatio...
3 days ago
Machine Learning Engineering Manager - Core Ads Ranking
$230K - $322K *
Accelerate progress at shaping foundational models and user understanding while collaborating with cross-functional teams to drive impactful machine learning initiatives and mentor top talent in a dyn...
3 days ago
Account Manager, Client Development & Renewals (East Coast / Mid-Atlantic)
$123K - $135K *
Engage in a growth-focused role managing existing accounts, driving renewals and expansion. Collaborate with teams to identify opportunities, ensure customer satisfaction, and achieve revenue goals wh...
3 days ago
Director - Pharma Meetings, Account and Operations
$95K - $123K *
Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...
Reposted 3 days ago
SAP Senior Solution Architect, Manufacturing
$150K - $232K *
Lead transformative SAP solutions in manufacturing, optimizing processes and driving innovation. Collaborate with teams to deliver value-driven results, leveraging deep expertise in SAP S/4HANA and bu...
3 days ago
$120K - $150K *
Join a team that's driving innovative demand generation strategies. You'll lead integrated campaigns, collaborate across departments, and optimize performance to generate qualified leads and pipeline...
3 days ago
Senior Software Engineer- Backend GoLang (Remote)
$89K - $170K *
Pioneer innovative software solutions by developing and maintaining high-quality applications. Collaborate within a cross-functional team to enhance system performance and reliability, ensuring except...
Reposted 3 days ago
National Field Development Specialist - Foot and Ankle & Trauma
$131K - $240K *
Shape the future of training and development in orthopedic medical devices, enhancing sales effectiveness and fostering strong partnerships across teams. Drive learning initiatives and support surgica...
Reposted 3 days ago
Compliance Policy, Training & Communications Lead (remote)
$100K - $130K *
Champion compliance excellence by leading training and communication initiatives that enhance understanding and adherence to policies across the organization. Drive engagement and elevate the complian...
Reposted 3 days ago
Territory Sales Representative, Implants MIS
$82K - $150K *
Accelerate growth by driving new customer acquisition and expanding market share in the dental implant sector. Leverage your sales expertise to build relationships, convert competitive accounts, and p...
Reposted 3 days ago
Assoc Dir, Neuro Thought Leader Liaison (West region)
$190K - $225K *
Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...
Reposted 3 days ago
Territory Sales Representative, Dental Implants MIS
$82K - $150K *
Join a team that's driving growth in the dental implant market by aggressively prospecting and converting new customers. Leverage your sales expertise to expand market share and position value-oriente...
Reposted 3 days ago
Assoc Dir, Neuro Thought Leader Liaison (Midwest Region)
$190K - $225K *
Transform relationships with key opinion leaders in rare neurological diseases, providing strategic insights and guidance to inform brand strategies and enhance engagement across medical and commercia...
Reposted 3 days ago
Lead Client Partner - Business Development
$210K - $300K *
Partner with us to drive strategic sales initiatives, cultivate CxO relationships, and identify growth opportunities, all while enhancing customer satisfaction and delivering impactful business outcom...
Reposted 3 days ago
$195K - $225K *
Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...
3 days ago
Manager, Sourcing, Indirect, Americas
$100K - $125K *
Join our dynamic team to develop innovative sourcing strategies, lead supplier negotiations, and drive value creation within the Americas, contributing significantly to our growth and sustainability g...
Reposted 3 days ago
Sales Manager Specialty Fluids
$100K - $120K *
Empower your career as a Sales Manager in the Specialty Fluids sector, driving growth through strategic account management and lead generation while collaborating with diverse teams across North Ameri...
Reposted 3 days ago
$80K - $95K *
Join us to lead a dynamic team in optimizing revenue cycle operations for multiple clients. Drive continuous improvement and ensure client satisfaction while managing performance metrics and fostering...
3 days ago
$100K - $125K *
Champion customer quality initiatives by collaborating with cross-functional teams to enhance satisfaction, resolve issues, and drive continuous improvement in the Data Center Chiller business. Engage...
3 days ago
$110K - $130K *
Drive growth by building and scaling credit card acquisition channels through innovative affiliate partnerships, targeted paid search, and social programs, while collaborating with cross-functional te...
3 days ago
Senior Engineering Consultant - Civil/Construction
$110K - $130K *
Champion client success by leading complex commercial real estate projects, managing multi-site portfolios, and providing senior technical expertise to multidisciplinary teams, ensuring effective deli...
Reposted 3 days ago
Clinical Specialist Western Canada
$80K - $111K *
Partner with us to transform patient care in advanced cochlear implant solutions. Build trusted relationships, execute strategic plans, and improve outcomes by leveraging clinical expertise and consul...
Reposted 3 days ago
$148K - $214K *
Innovate customer experience and automation solutions to streamline real estate closings. Drive strategy, prioritize product roadmaps, and collaborate across teams to enhance operational efficiency an...
3 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.