Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$120K - $150K *
Lead the charge in advancing pharmaceutical analytical methods and standards. Drive complex studies, support regulatory compliance, and mentor scientific talent while championing method development an...
3 weeks ago
$110K - $130K *
Accelerate drug discovery by leading in vitro ADME studies. Drive impactful research through innovative methods and data interpretation, advancing IND-enabling programs and ensuring regulatory complia...
2 weeks ago
$143K - $265K *
Join a team that's advancing drug discovery through cutting-edge metabolomics and lipidomics. Utilize high-throughput mass spectrometry and AI to drive insights, collaborating across functions to deli...
2 weeks ago
$110K - $130K *
Accelerate progress at the forefront of rubber and tire technology innovations. Leverage your expertise to drive product development, influence strategy, and lead research initiatives in a role that s...
1 week ago
Senior Research Scientist; Chemical Development
$93K *
Contribute to innovative chemical synthesis, purification, and process optimization. Drive research initiatives by leading projects on target compounds, involving literature analysis and advanced labo...
1 week ago
$100K - $130K *
Lead the charge in advancing NOAA's satellite sensor calibration efforts, ensuring the quality of atmospheric data while addressing instrument anomalies and enhancing predictive models through innovat...
6 days ago
$80K - $95K *
Lead the charge in advancing in vitro and in vivo release testing through method development and compliance with FDA regulations. Engage with cross-functional teams to ensure timely project delivery a...
2 days ago
Principal Scientist - Bioseparation & Analytical Development
$120K - $145K *
Lead the charge in advancing bioseparation analytical methods for large molecules. Drive innovation in biologics characterization, supporting drug development through hands-on execution and scientific...
Reposted 1 week ago
Principal Scientist-Analytical Research & Development (ARD)
$140K - $155K *
Engage in the development and implementation of analytical methods for APIs, ensuring compliance with industry standards. Collaborate with project teams while applying advanced techniques and leading...
Reposted 1 week ago
Principal Regulatory Scientist
$120K - $145K *
Shape the future of regulatory science by leading projects, nurturing client relationships, and driving business growth in environmental compliance. Utilize your expertise in chemical regulation to de...
1 week ago
$172K - $220K *
Transform scientific consulting by leading projects leveraging computer science and electrical engineering expertise. Engage in analysis, develop business proposals, and present findings to clients to...
4 weeks ago
Principal Scientist - BioPharma LBA
$106K - $140K *
Unlock potential by leading and mentoring as a Principal Scientist in bioanalytical validation, overseeing early drug discovery, preclinical work, and clinical trials, while fostering innovative labor...
Reposted 3 weeks ago
Principal Scientist - BioPharma LBA
$106K - $140K *
Elevate your career as you lead bioanalytical validation and studies, mentoring teams while ensuring excellence in drug discovery and regulatory compliance across bioanalysis and toxicology...
Reposted 3 weeks ago
$90K - $100K *
Unlock potential by leading the development, validation, and commercialization of innovative food products. Collaborate across functions to drive quality, safety, and efficiency while managing complex...
2 weeks ago
$90K - $100K *
Lead the charge in the development and commercialization of innovative food products. Collaborate cross-functionally, applying advanced food science techniques to meet consumer needs and ensure compli...
2 weeks ago
Senior Scientist/Team Leader – Bioprocess Development
$107K - $161K *
Lead a team in downstream process development focused on monoclonal antibodies, ensuring production efficiency and therapeutic advancement through innovative purification strategies. Collaborate with...
1 week ago
Scientist/Sr. Scientist/Principal Scientist
$110K - $130K *
Innovate in process chemistry by leading research, optimizing routes, and supporting GMP manufacturing for small-molecule APIs. Drive technical strategies and mentor a team while collaborating with cr...
6 days ago
Principal Scientist, Biomarker Bioanalytical Sciences
$141K - $188K *
Unlock potential by leading biomarker and bioanalytical strategies to support clinical development. Collaborate with internal teams and CROs, ensuring scientifically rigorous approaches are aligned wi...
Today
Principal Scientist, Biomarker Bioanalytical Sciences
$141K - $188K *
Empower clinical development through scientific leadership in biomarker and bioanalytical strategies, guiding assay design, CRO oversight, and regulatory submissions in a fast-paced environment...
Yesterday
$120K - $145K *
Join our innovative team as a Product Scientist, applying your expertise in computational and medicinal chemistry to optimize small molecules and drive partner programs forward, while shaping the futu...
1 week ago
$120K - $145K *
Lead scientific partnerships, optimizing small molecule therapies using your expertise in medicinal chemistry and computational methods. Collaborate across disciplines to develop innovative modeling s...
1 week ago
Principal Research Scientist - Risk
$150K - $180K *
Lead transformative research in infrastructure risk and resilience. Develop advanced models, drive decision-making, and guide a team to improve utility management practices and safeguard critical asse...
2 weeks ago
Principal Scientist, Technical Services
$110K - $150K *
Lead the charge in pharmaceutical innovations by providing technical expertise for solid oral dosage products, ensuring efficient manufacturing and continuous process improvements throughout the produ...
2 weeks ago
Principal Scientist, Process Chemistry
$165K - $185K *
Lead the charge in advancing drug substance processes, collaborating across teams to drive innovation and regulatory success. Leverage expertise to transform scientific ideas into viable commercial so...
Reposted 1 week ago
Senior / Principal Scientist, Biochemistry
$158K - $184K *
Join a team that's dedicated to advancing drug discovery by designing and implementing innovative biochemical assays to characterize small molecule interactions and drive lead optimization in a collab...
2 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.